316 research outputs found
Probability transport on the Fock space of a disordered quantum spin chain
Within the broad theme of understanding the dynamics of disordered quantum
many-body systems, one of the simplest questions one can ask is: given an
initial state, how does it evolve in time on the associated Fock-space graph,
in terms of the distribution of probabilities thereon? A detailed quantitative
description of the temporal evolution of out-of-equilibrium disordered quantum
states and probability transport on the Fock space, is our central aim here. We
investigate it in the context of a disordered quantum spin chain which hosts a
disorder-driven many-body localisation transition. Real-time
dynamics/probability transport is shown to exhibit a rich phenomenology, which
is markedly different between the ergodic and many-body localised phases. The
dynamics is for example found to be strongly inhomogeneous at intermediate
times in both phases, but while it gives way to homogeneity at long times in
the ergodic phase, the dynamics remain inhomogeneous and multifractal in nature
for arbitrarily long times in the localised phase. Similarly, we show that an
appropriately defined dynamical lengthscale on the Fock-space graph is directly
related to the local spin-autocorrelation, and as such sheds light on the
(anomalous) decay of the autocorrelation in the ergodic phase, and lack of it
in the localised phase.Comment: 20 pages, 16 figure
Ocean processes at the Antarctic continental slope
The Antarctic continental shelves and slopes occupy relatively small areas, but, nevertheless, are important for global climate, biogeochemical cycling and ecosystem functioning. Processes of water mass transformation through sea ice formation/melting and ocean-atmosphere interaction are key to the formation of deep and bottom waters as well as determining the heat flux beneath ice shelves. Climate models, however, struggle to capture these physical processes and are unable to reproduce water mass properties of the region. Dynamics at the continental slope are key for correctly modelling climate, yet their small spatial scale presents challenges both for ocean modelling and for observational studies. Cross-slope exchange processes are also vital for the flux of nutrients such as iron from the continental shelf into the mixed layer of the Southern Ocean. An © 2014 The Authors
An algebraic theory of complexity for valued constraints: Establishing a Galois connection
Abstract. The complexity of any optimisation problem depends critically on the form of the objective function. Valued constraint satisfaction problems are discrete optimisation problems where the function to be minimised is given as a sum of cost functions defined on specified subsets of variables. These cost functions are chosen from some fixed set of available cost functions, known as a valued constraint language. We show in this paper that when the costs are non-negative rational numbers or infinite, then the complexity of a valued constraint problem is determined by certain algebraic properties of this valued constraint language, which we call weighted polymorphisms. We define a Galois connection between valued constraint languages and sets of weighted polymorphisms and show how the closed sets of this Galois connection can be characterised. These results provide a new approach in the search for tractable valued constraint languages
Focal cerebral ischemia in the TNFalpha-transgenic rat
<p>Abstract</p> <p>Background</p> <p>To determine if chronic elevation of the inflammatory cytokine, tumor necrosis factor-α (TNFα), will affect infarct volume or cortical perfusion after focal cerebral ischemia.</p> <p>Methods</p> <p>Transgenic (TNFα-Tg) rats overexpressing the murine TNFα gene in brain were prepared by injection of mouse DNA into rat oocytes. Brain levels of TNFα mRNA and protein were measured and compared between TNFα-Tg and non-transgenic (non-Tg) littermates. Mean infarct volume was calculated 24 hours or 7 days after one hour of reversible middle cerebral artery occlusion (MCAO). Cortical perfusion was monitored by laser-Doppler flowmetry (LDF) during MCAO. Cortical vascular density was quantified by stereology. Post-ischemic cell death was assessed by immunohistochemistry and regional measurement of caspase-3 activity or DNA fragmentation. Unpaired <it>t </it>tests or analysis of variance with post hoc tests were used for comparison of group means.</p> <p>Results</p> <p>In TNFα-Tg rat brain, the aggregate mouse and rat TNFα mRNA level was fourfold higher than in non-Tg littermates and the corresponding TNFα protein level was increased fivefold (p ≤ 0.01). Infarct volume was greater in TNFα-Tg rats than in non-Tg controls at 24 hours (p ≤ 0.05) and 7 days (p ≤ 0.01). Within the first 10 minutes of MCAO, cortical perfusion measured by LDF was reduced in TNFα-Tg rats (p ≤ 0.05). However, regional vascular density was equivalent between TNFα-Tg and non-Tg animals (p = NS). Neural cellular apoptosis was increased in transgenic animals as shown by elevated caspase-3 activity (p ≤ 0.05) and DNA fragmentation (p ≤ 0.001) at 24 hours.</p> <p>Conclusion</p> <p>Chronic elevation of TNFα protein in brain increases susceptibility to ischemic injury but has no effect on vascular density. TNFα-Tg animals are more susceptible to apoptotic cell death after MCAO than are non-Tg animals. We conclude that the TNFα-Tg rat is a valuable new tool for the study of cytokine-mediated ischemic brain injury.</p
Recommended from our members
The Monstrous ‘White Theory Boy’: Symbolic Capital, Pedagogy and the Politics of Knowledge
This article presents a critical uncovering of the continued dominance of whiteness and maleness in processes and practices of knowledge formation. Tracking the figure of the ‘white theory boy’ or ‘dead white man’ across experiential accounts of theory, scholarship on canonicity, and pedagogical strategies, the article demonstrates his enduring authority in theoretical knowledge making and dissemination. Where this article moves somewhere different is its suggestion that a space of sympathy be extended to this hegemonic figure. Though the dominance of the ‘white theory boy’ undoubtedly perpetuates inequalities throughout social theoretic thought, it is necessary to locate a new method of tackling such ingrained problems. Though extending sympathy to the ‘white theory boy’ is perhaps initially counter-intuitive, my suggestion is that he does not hold the sort of monolithic power we might first assume. Bringing an intersectional analysis of gender, class, ‘race’ and ethnicity to bear on this figure, creates a space in which a more critical and fine-grained account of the relationship between power, knowledge, and social status can be uncovered. It is through extending this space of sympathy and mutual cooperation to ‘white theory boys’ that the practical and conceptual machinations of their power are further revealed. From here a more thorough dismantling of this power becomes possible
- …