Write-up and dissemination of undergraduate and postgraduate research at the University of Rwanda: a cross-sectional study

Introduction: research is essential in all areas of health development. However, medical students and residents frequently lack the time and training on performing research. This is especially prevalent in resource-limited settings. We aimed to compare the word counts of undergraduate and postgraduate dissertations with published projects in Rwanda, and to identify the proportion of postgraduate pediatric research projects that have been published since 2012. Methods: retrospective, cross-sectional study of undergraduate and postgraduate research dissertations at the University of Rwanda. Dissertations were then compared to randomly selected published papers of Rwandan research. Each IMRaD (Introduction, Methodology, Results and Discussion) section word count was compared using Student's t-test. Results: 19/190 (10%) undergraduate dissertations and 22/41 (54%) postgraduate dissertations, were available in electronic format for word-count analysis. The mean total word count for postgraduate dissertations (5163 words) was significantly longer (p<0.001) than the randomly selected peer-reviewed journal articles (2959 words). Each section of the IMRaD structure of postgraduate dissertations was significantly longer than those of the control group. Undergraduates used a similar number of words to published papers, but used significantly more tables and figures. Of the 41 postgraduate dissertations, only four (10%), were published in peer-reviewed journals. Conclusion: this is the first study to assess the writing style of Rwandan medical students and pediatric postgraduate residents. A simple step to increase dissemination of research findings would be for institutions to modify academic regulations so that students write-up in manuscript form rather than dissertation format

Altered Breast Development in Young Girls from an Agricultural Environment

In several human populations, the age at which female breast development begins is reported to have declined over the last five decades. Much debate has occurred over whether this reported decline has actually occurred and what factors contribute to it. However, geographical patterns reflecting earlier developmental onset in some human populations suggest environmental factors influence this phenomenon. These factors include interactions between genetic makeup, nutrition, and possible cumulative exposure to estrogens, both endogenous as well as environmental beginning during in utero development. We examined the onset of breast development in a group of peripubertal girls from the Yaqui Valley of Sonora, Mexico. We observed that girls from valley towns, areas using modern agricultural practices, exhibited larger breast fields than those of girls living in the foothills who exhibited similar stature [e.g., weight, height, body mass index (BMI)], and genetic background. Further, girls from valley towns displayed a poorly defined relationship between breast size and mammary gland development, whereas girls from the Yaqui foothills, where traditional ranching occurs, show a robust positive relationship between breast size and mammary size. The differences noted were obtained by a medically based exam involving morphometric analysis and palpation of tissues, in contrast to visual staging alone. In fact, use of the Tanner scale, involving visual staging of breast development for puberty, detected no differences between the study populations. Mammary tissue, determined by palpation, was absent in 18.5% of the girls living in agricultural areas, although palpable breast adipose tissue was present. No relationship was seen between mammary diameter and weight or BMI in either population. These data suggest that future in-depth studies examining mammary tissue growth and fat deposition in breast tissue are required if we are to understand environmental influences on these phenomena

The runaway binary LP 400−22 is leaving the Galaxy

We present optical spectroscopy, astrometry, radio and X-ray observations of the runaway binary LP 400−22. We refine the orbital parameters of the system based on our new radial velocity observations. Our parallax data indicate that LP 400−22 is significantly more distant (3σ lower limit of 840 pc) than initially predicted. LP 400−22 has a tangential velocity in excess of 830 km s^−1; it is unbound to the Galaxy. Our radio and X-ray observations fail to detect a recycled millisecond pulsar companion, indicating that LP 400−22 is a double white dwarf system. This essentially rules out a supernova runaway ejection mechanism. Based on its orbit, a Galactic Centre origin is also unlikely. However, its orbit intersects the locations of several globular clusters; dynamical interactions between LP 400−22 and other binary stars or a central black hole in a dense cluster could explain the origin of this unusual binary

Retinopathy of prematurity in Rwanda: a prospective multi-centre study following introduction of screening and treatment services.

OBJECTIVES: To investigate risk factors for retinopathy of prematurity (ROP) in a newly established ROP screening and management programme in Rwanda, Africa. METHODS: In this multi-centre prospective study 795/2222 (36%) babies fulfilled the inclusion criteria (gestational age (GA)  30 weeks and BW > 1500 g, one of whom required treatment. In univariate analysis the following were associated with any ROP: increasing number of days on supplemental oxygen (OR 2.1, CI 1.5-3.0, P < 0.001), low GA (OR 3.4, CI 1.8-6.4, P < 0.001), low BW (OR 2.3, CI 1.5-3.4, P < 0.001), at least one episode of hyperglycaemia ≥ 150 mg/dl (OR 6.6, CI 2.0-21.5, P < 0.001), blood transfusion (OR 3.5, CI 1.6-7.4, P < 0.001) or sepsis (OR 3.2, CI 1.2-8.6, P = 0.01). In multivariate analysis longer exposure to supplemental oxygen (OR 2.1, CI 1.2-3.6, P = 0.01) and hyperglycaemia (OR 3.5, CI 1.0-12.4, P = 0.05) remained significant. CONCLUSIONS: ROP has become an emerging health problem in Rwanda, requiring programmes for screening and treatment. ROP screening is indicated beyond the 2013 American Academy guidelines. Improved quality of neonatal care, particularly oxygen delivery and monitoring is needed

Perceived attitudes of the importance and barriers to research amongst Rwandan interns and pediatric residents – a cross-sectional study

Abstract Background Globally, interns and residents face significant challenges with respect to research activity. Despite this, they are motivated and have an interest in undertaking research. To date, there has been no research regarding the perceived attitudes towards research activities amongst Rwandan residents and interns. Objectives The primary objective of this study was to describe the perceived attitudes regarding the educational benefits and barriers surrounding research activity amongst interns and residents, and to identify any differences between these groups. The secondary objective was to describe the research methods used by interns and residents in Rwanda. Methods A cross-sectional descriptive study of interns and pediatric trainees at the University of Rwanda. An online questionnaire using Likert scale questions was sent electronically to eligible participants. Results A total of sixty participants (38 interns and 22 pediatric residents) responded to the survey. Both groups acknowledged the educational importance of undertaking research, with interns reporting this more than residents. Both groups identified the following as barriers to research: faculty lacking time to mentor, lack of funding, lack of statistical support, and lack of faculty experienced in conducting research. Interns (87%) were much more likely to have undertaken retrospective research than pediatric residents (14%). Few interns or residents submitted their research for publication (27%). Conclusions Both interns and residents understood the importance of research, but many barriers exist. Increasing the time available for experienced faculty members to supervise research is challenging due to low faculty numbers. Novel solutions will need to be found as well as expanding the time for trainees to perform research

Altered Breast Development in Young Girls from an Agricultural Environment-1

<p><b>Copyright information:</b></p><p>Taken from "Altered Breast Development in Young Girls from an Agricultural Environment"</p><p>Environmental Health Perspectives 2006;114(3):471-475.</p><p>Published online Jan 2006</p><p>PMCID:PMC1392245.</p><p>This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.</p

Affirmative Action: A Review of Psychological and Behavioral Research

In September of 1995, the Scientific Affairs Committee of the Society for Industrial and Organizational Psychology created a subcommittee to review psychological and behavioral research on affirmative action. That review follows, and the nine members of the subcommittee are the authors of this report. To provide some context, we begin with a brief review of important legislation and case law, and distinguish affirmative action from related concepts. A more detailed review of these matters will be provided by a second subcommittee. We then turn to the heart of the review -- research on evaluations of affirmative action and affirmative action plans (AAPs). After that, we review research on how the presence of an AAP affects non-target group members\u27 perceptions of target group members, and the relations between target group members and non-target group members. We then review corresponding research on the psychological and behavioral effects of affirmative action on target group members themselves. To provide additional context, we briefly discuss the economic effects of affirmative action on target groups and on organizations. We close by drawing some general conclusions, by discussing the limitations of current knowledge, and by outlining some needed research