INVESTMENT ANALYSIS OF REPLACING ENDOPHYTE-INFECTED WITH ENDOPHYTE-FREE TALL FESCUE PASTURES

Cattle consuming tall fescue pastures infected with the endophyte Neotyphodium coenophialum often suffer physiological disorders that reduce animal performance. One solution is to replace endophyte-infected tall fescue pastures with an endophyte-free mixture. A benefit-cost analysis was conducted to determine the profitability of pasture restoration. The profitability of this action depends on the percentage of endophyte in existing pastures, the discount rate, and the stand life of the endophyte-free tall fescue variety. Our benefit-cost analysis results indicate that in order for pasture replacement to be profitable, the existing pastures must be infected with more than 16.1% of the endophyte, assuming the stand life of endophyte-free tall fescue is 12 years and the discount rate is three per cent. Additionally, a sensitivity analysis was conducted to determine the impact on the critical infestation level when the following parameters are changed: the discount rate, the baseline calving rates, and the pasture stand life. This research provides farmers with a practical investment analysis model for replacing endophyte-infected with endophyte-free tall fescue pastures.Land Economics/Use,

Routine Changing of Intravenous Administration Sets Does Not Reduce Colonization or Infection in Central Venous Catheters

Objective: To determine the effect of routine intravascular administration-set changes on central venous catheter (CVC) colonization and catheter related bacteremia (CRB). Design: Prospective, randomised controlled trial Setting: 18-bed ICU in a University-affiliated, tertiary referral hospital. Participants: 404 chlorhexidine and silver sulfadiazine coated multi-lumen CVCs from 251 intensive care unit (ICU) patients. Interventions: After ethical approval, CVCs inserted in ICU and in situ on Day 4 were randomised to have their administration-sets changed on Day 4 (n = 203) or not at all (n = 201). Fluid container and blood product administration-set use was limited to 24 hours. CVCs were removed (Day 7, not required or suspected infection), and cultured for colonization ( 15 cfu). Medical and laboratory staff were blinded. CRB was diagnosed by a blinded intensivist using strict definitions. Data was collected on; catheter life, CVC site, APACHE II score, patient age, diagnosis, hyperglycemia, hypoalbuminemia, immune status, number of fluid containers and intravenous injections, propofol, blood, TPN or lipid infusion. Results: There were 10 colonized CVCs in the set change group and 19 in the no change group. This was not a statistically significant difference on Kaplan Meier survival analysis (Effect Size = 0.09, Log Rank = 0.87, df = 1, p = 0.35). There were 3 cases of CRB per group. Logistic regression found that burns diagnosis and increased ICU stay were the only factors that significantly predicted colonization (p < 0.001). Conclusions: Intravenous administration-sets can be used for 7-days. Routine administration-set changes are unnecessary before this time

Intelligent Advertisement Selection

A mechanism for intelligently selecting advertisements to present to users in conjunction with videos. The mechanism identifies and analyzes past user interactions with advertisements, and uses this analysis to intelligently inform advertisement selection. Past user interactions may include watching an ad all the way through without skipping it; sharing an ad; “liking” or up-voting an ad; returning to a website associated with the content sharing platform to re-watch an ad; re-watching an ad by “rewinding” to the beginning of the ad; visiting or subscribing to a “channel” associated with the advertised product or with the advertiser; commenting on the ad; and so forth. The mechanism can be employed in conjunction with other advertisement selection techniques, or can be employed independently

A survey of the breast care nurse role in the provision of information and supportive care to Australian women diagnosed with breast cancer

Aim: To explore the role of the Australian breast care nurse in the provision of information and support to women with breast cancer, with a focus on the differences experienced depending on geographic work context. Design: A cross-sectional study. Methods: This study conducted in 2013, involved surveying BCNs currently working in Australia, using a newly developed self-report online survey. Results: Fifty breast care nurses completed the survey, 40% from major cities, 42% from inner regional Australia and 18% from outer regional, remote and very remote Australia. Patterns of service indicated higher caseloads in urban areas, with fewer kilometres served. Breast care nurses in outer regional, remote and very remote areas were less likely to work in multi-disciplinary teams and more likely to spend longer consulting with patients. Breast care nurses reported they undertook roles matching the competency standards related to the provision of education, information and support; however, there were barriers to fulfilling competencies including knowledge based limitations, time constraints and servicing large geographical areas. Conclusions: This was the first Australian study to describe the role of the breast care nurse nationally and the first study to investigate breast care nurses perceived ability to meet a selection of the Australian Specialist Breast Nurse Competency Standards. Important differences were found according to the geographical location of breast care nurses

Slow Nominations and Confirmations Pose a Threat to National Security

Experts have long agreed the transition from one presidential administration to another is a vulnerable time for the country, and that new presidents and Congress each have an obligation to fill top national security positions as quickly as possible. As the pandemic, events in Ukraine and other global challenges have demonstrated, continuity in national security leadership is crucial for the security of the U.S. and its allies and partners. Data from the Partnership for Public Service's Center for Presidential Transition, however, reveals chronic delays at nearly every step of the nomination and confirmation process--even for the national security positions that all stakeholders agree are essential to minimize threats during the first months of a new administration