A Possible Massive Asteroid Belt Around zeta Lep

We have used the Keck I telescope to image at 11.7 microns and 17.9 microns the dust emission around zeta Lep, a main sequence A-type star at 21.5 pc from the Sun with an infrared excess. The excess is at most marginally resolved at 17.9 microns. The dust distance from the star is probably less than or equal to 6 AU, although some dust may extend to 9 AU. The mass of observed dust is \~10^22 g. Since the lifetime of dust particles is about 10,000 years because of the Poytning-Robertson effect, we robustly estimate at least 4 10^26 g must reside in parent bodies which may be asteroids if the system is in a steady state and has an age of ~300 Myr. This mass is approximately 200 times that contained within the main asteroid belt in our solar system.Comment: 12 pages, 3 figures, ApJL in pres

Correlations of Globular Cluster Properties: Their Interpretations and Uses

Correlations among the independently measured physical properties of globular clusters (GCs) can provide powerful tests for theoretical models and new insights into their dynamics, formation, and evolution. We review briefly some of the previous work, and present preliminary results from a comparative study of GC correlations in the Local Group galaxies. The results so far indicate that these diverse GC systems follow the same fundamental correlations, suggesting a commonality of formative and evolutionary processes which produce them.Comment: An invited review, to appear in "New Horizons in Globular Cluster Astronomy", eds. G. Piotto, G. Meylan, S.G. Djorgovski, and M. Riello, ASPCS, in press (2003). Latex file, 8 pages, 5 eps figures, style files include

The Ontology Lookup Service: more data and better tools for controlled vocabulary queries

The Ontology Lookup Service (OLS) (http://www.ebi.ac.uk/ols) provides interactive and programmatic interfaces to query, browse and navigate an ever increasing number of biomedical ontologies and controlled vocabularies. The volume of data available for querying has more than quadrupled since it went into production and OLS functionality has been integrated into several high-usage databases and data entry tools. Improvements have been made to both OLS query interfaces, based on user feedback and requirements, to improve usability and service interoperability and provide novel ways to perform queries

A Megacam Survey of Outer Halo Satellites. IV. Two foreground populations possibly associated with the Monoceros substructure in the direction of NGC2419 and Koposov2

The origin of the Galactic halo stellar structure known as the Monoceros ring is still under debate. In this work, we study that halo substructure using deep CFHT wide-field photometry obtained for the globular clusters NGC2419 and Koposov2, where the presence of Monoceros becomes significant because of their coincident projected position. Using Sloan Digital Sky Survey photometry and spectroscopy in the area surrounding these globulars and beyond, where the same Monoceros population is detected, we conclude that a second feature, not likely to be associated with Milky Way disk stars along the line-of-sight, is present as foreground population. Our analysis suggests that the Monoceros ring might be composed of an old stellar population of age t ~ 9Gyr and a new component ~ 4Gyr younger at the same heliocentric distance. Alternatively, this detection might be associated with a second wrap of Monoceros in that direction of the sky and also indicate a metallicity spread in the ring. The detection of such a low-density feature in other sections of this halo substructure will shed light on its nature.Comment: 10 pages, 10 figures, accepted for publication in Ap

The Next Generation Virgo Cluster Survey (NGVS). XVIII. Measurement and Calibration of Surface Brightness Fluctuation Distances for Bright Galaxies in Virgo (and Beyond)

We describe a program to measure surface brightness fluctuation (SBF) distances to galaxies observed in the Next Generation Virgo Cluster Survey (NGVS), a photometric imaging survey covering $104~deg^2$ of the Virgo cluster in the ${u}^*,g,i,z$ bandpasses with the Canada-France Hawaii Telescope. We describe the selection of the sample galaxies, the procedures for measuring the apparent $i$-band SBF magnitude $\bar{i}$, and the calibration of the absolute $\bar{M}_i$ as a function of observed stellar population properties. The multi-band NGVS data set provides multiple options for calibrating the SBF distances, and we explore various calibrations involving individual color indices as well as combinations of two different colors. Within the color range of the present sample, the two-color calibrations do not significantly improve the scatter with respect to wide-baseline, single-color calibrations involving $u^{*}$. We adopt the ${u}^*{-}z$ calibration as reference for the present galaxy sample, with an observed scatter of 0.11 mag. For a few cases that lack good ${u}^*$ photometry, we use an alternative relation based on a combination of $g{-}i$ and $g{-}z$ colors, with only a slightly larger observed scatter of 0.12 mag. The agreement of our measurements with the best existing distance estimates provides confidence that our measurements are accurate. We present a preliminary catalog of distances for 89 galaxies brighter than $B_T\approx13.0$ mag within the survey footprint, including members of the background M and W Clouds at roughly twice the distance of the main body of the Virgo cluster. The extension of the present work to fainter and bluer galaxies is in progress.Comment: ApJ accepte

Mise en place de l'extraction liquide-liquide en microsystèmes établir des écoulements segmentés à façon pour optimiser le transfert de masse

National audienceLiquid-liquid extraction is commonly used for radiochemical analysis. When miniaturized, it can benefitfrom the advantages of microfluidic tools i.e. possible coupling, precise control of the interfacial areabetween the aqueous and organic phases, and contact time. A first study, dedicated to liquid-liquidextraction with parallel flows of europium diluted in nitric acid by the N,N′-dimethyl-N,N′-dibutyltetradecylmalonic diamide [1, 2], allowed us to highlight the limitations of parallel flows for aslow chemical system. One way to optimize yields of extraction of the kinetically slow systems is toincrease the specific interfacial area. For this reason, segmented flows formation and characteristicswere investigated, as a function of the physicochemical properties of a biphasic system, flow rates andthe dimensions of a focalized flux junction. In the following, two multiphase models of the droplets sizecorresponding to the transition and dripping regimes were validated and will be used for theoptimization of the specific interfacial area.L’extraction liquide-liquide est couramment utilisée pour les analyses radiochimiques. Miniaturisée,elle peut bénéficier des avantages des outils microfluidiques qui sont la possibilité de réaliser descouplages, le contrôle précis de l’aire interfaciale entre les phases aqueuse et organique en présence,et des temps de contact. Une première étude, dédiée à l’extraction liquide-liquide en flux parallèlesd’europium en milieu nitrique par le N,N’-dimethyl N,N’-dibutyl tetradecylmalonamide [1, 2], a permisde mettre en évidence les limitations des flux parallèles pour un système chimique lent. Une façond’optimiser les rendements d’extraction des systèmes cinétiquement lents est de mettre en œuvre desécoulements permettant d’augmenter l’aire interfaciale spécifique. C’est pourquoi nous étudions laformation d’écoulements segmentés à façon en fonction des propriétés physico-chimiques d’un systèmechimique biphasique, des débits et des dimensions d’une jonction en flux focalisé. L’utilisation de deuxmodèles de calcul des tailles de gouttes en régimes d’écoulements transitoire

Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women

In a population-based case-control study, we explored the associations between 42 polymorphisms in seven genes in this region and non-small cell lung cancer (NSCLC) risk among Caucasian (364 cases; 380 controls) and African American (95 cases; 103 controls) women. Two TERT region SNPs, rs2075786 and rs2853677, conferred an increased risk of developing NSCLC, especially among African American women, and TERT-rs2735940 was associated with a decreased risk of lung cancer among African Americans. Five of the 20 GHR polymorphisms and SEPP1-rs6413428 were associated with a marginally increased risk of NSCLC among Caucasians. Random forest analysis reinforced the importance of GHR among Caucasians and identified AMACR, TERT, and GHR among African Americans, which were also significant using gene-based risk scores. Smoking-SNP interactions were explored, and haplotypes in TERT and GHR associated with NSCLC risk were identified. The roles of TERT, GHR, AMACR and SEPP1 genes in lung carcinogenesis warrant further exploration

Self-organized criticality in the hysteresis of the Sherrington - Kirkpatrick model

We study hysteretic phenomena in random ferromagnets. We argue that the angle dependent magnetostatic (dipolar) terms introduce frustration and long range interactions in these systems. This makes it plausible that the Sherrington - Kirkpatrick model may be able to capture some of the relevant physics of these systems. We use scaling arguments, replica calculations and large scale numerical simulations to characterize the hysteresis of the zero temperature SK model. By constructing the distribution functions of the avalanche sizes, magnetization jumps and local fields, we conclude that the system exhibits self-organized criticality everywhere on the hysteresis loop.Comment: 4 pages, 4 eps figure

Tubular structures of GaS

In this Brief Report we demonstrate, using density-functional tight-binding theory, that gallium sulfide (GaS) tubular nanostructures are stable and energetically viable. The GaS-based nanotubes have a semiconducting direct gap which grows towards the value of two-dimensional hexagonal GaS sheet and is in contrast to carbon nanotubes largely independent of chirality. We further report on the mechanical properties of the GaS-based nanotubes

Different Transport Pathways of Individual Precursor Proteins in Mitochondria

Transport of mitochondrial precursor proteins into mitochondria of Neurospora crassa was studied in a cellfree reconstituted system. Precursors were synthesized in a reticulocyte lysate programmed with Neurospora mRNA and transported into isolated mitochondria in the absence of protein synthesis. Uptake of the following precursors was investigated: apocytochrome c, ADP/ATP carrier and subunit 9 of the oligomycin-sensitive ATPase. Addition of high concentrations of unlabelled chemically prepared apocytochrome c (1–10 μM) inhibited the appearance in the mitochondrial of labelled cytochrome c synthesized in vitro because the unlabelled protein dilutes the labelled one and because the translocation system has a limited capacity [apparent V is 1–3 pmol × min−1× (mg mitochondrial protein)−1]. Concentrations of added apocytochrome c exceeding the concentrations of precursor proteins synthesized in vitro by a factor of about 104 did not inhibit the transfer of ADP/ATP carrier or ATPase subunit 9 into mitochondria. Carbonylcyanide m-chlorophenylhydrazone, an uncoupler of oxidative phosphorylation, inhibited transfer in vitro of ADP/ATP carrier and of ATPase subunit 9, but not of cytochrome c. These findings suggest that cytochrome c and the other two proteins have different import pathways into mitochondria. It can be inferred from the data presented that different 'receptors' on the mitochondrial surface mediate the specific recognition of precursor proteins by mitochondria as a first step in the transport process