Alien Registration- Costigan, Louis A. (Bangor, Penobscot County)

https://digitalmaine.com/alien_docs/14286/thumbnail.jp

The association between sedentary behaviour and risk of anxiety: a systematic review

BACKGROUND: Previous research has linked sedentary behaviour (SB) to adverse physical health outcomes in adults and youth. Although evidence for the relationship between SB and mental health outcomes (e.g., depression) is emerging, little is known regarding risk of anxiety. METHODS: A systematic search for original research investigating the association between SB and risk of anxiety was performed using numerous electronic databases. A total of nine observational studies (seven cross-sectional and two longitudinal) were identified. Methodological quality of studies was assessed and a best-evidence synthesis was conducted. RESULTS: One cross-sectional study demonstrated a strong methodological quality, five cross-sectional studies demonstrated a moderate methodological quality and three studies (two cross-sectional one longitudinal) received a weak methodological quality rating. Overall, there was moderate evidence for a positive relationship between total SB and anxiety risk as well as for a positive relationship between sitting time and anxiety risk. There was inconsistent evidence for the relationship between screen time, television viewing time, computer use, and anxiety risk. CONCLUSION: Limited evidence is available on the association between SB and risk of anxiety. However, our findings suggest a positive association (i.e. anxiety risk increases as SB time increases) may exist (particularly between sitting time and risk of anxiety). Further high-quality longitudinal/interventional research is needed to confirm findings and determine the direction of these relationships

Pre- and Post-burst Radio Observations of the Class 0 Protostar HOPS 383 in Orion

There is increasing evidence that episodic accretion is a common phenomenon in Young Stellar Objects (YSOs). Recently, the source HOPS 383 in Orion was reported to have a $\times 35$ mid-infrared -- and bolometric -- luminosity increase between 2004 and 2008, constituting the first clear example of a class 0 YSO (a protostar) with a large accretion burst. The usual assumption that in YSOs accretion and ejection follow each other in time needs to be tested. Radio jets at centimeter wavelengths are often the only way of tracing the jets from embedded protostars. We searched the Very Large Array archive for the available observations of the radio counterpart of HOPS 383. The data show that the radio flux of HOPS 383 varies only mildly from January 1998 to December 2014, staying at the level of $\sim 200$ to 300 $\mu$Jy in the X band ($\sim 9$ GHz), with a typical uncertainty of 10 to 20 $\mu$Jy in each measurement. We interpret the absence of a radio burst as suggesting that accretion and ejection enhancements do not follow each other in time, at least not within timescales shorter than a few years. Time monitoring of more objects and specific predictions from simulations are needed to clarify the details of the connection betwen accretion and jets/winds in YSOs.Comment: ApJ Letters, in pres

Regulation of Phytochrome Gene Expression

In etiolated oat seedlings exposure to red light results in a decrease in the transcription of the phytochrome genes, the abundance of phytochrome mRNA, and the level of phytochrome protein. Phytochrome itself serves as the photoreceptor for the response of decreased mRNA and transcription levels. The decrease in phytochrome mRNA is sensitive to low levels of Pfr. Even green safelight is capable of inducing a decrease in phytochrome mRNA abundance. Barley phytochrome mRNA abundance is also dramatically down-regulated in response to red light but other plant species vary in their ability to decrease phytochrome mRNA abundance after red light treatment. Kinetic analysis and protein synthesis inhibitor data indicate that the abundance of phytochrome mRNA in oat seedlings may be regulated in part at the post-transcriptional level. Phytochrome mRNA may provide a useful model system for the investigation of posttranscriptional regulation of plant gene expression

Ailan Dans: Critical Issues in Torres Strait Islander Dance and the Curriculum

The question of the place of culture in the curriculum is complex and, at times, problematic for educators and community members. The issue is frequently at the heart of debates within fudigenous education. In particular, the critics of culturalism in fudigenous education argue that too often there is an over-emphasis on cultural issues to the detriment of other aspects of the curriculum. In addition, representations of fudigenous cultural practices often reify and essentialise Indigenous peoples. Despite these critiques, many Indigenous community members argue for respect for their cultural practices, standpoints and beliefs in education. This thesis considers the issues surrounding the incorporation of dance in the curriculum for Torres Strait Islander students. It does so through a critical discourse analysis of Torres Strait Islander community discourses. As with other Indigenous peoples throughout the world, Torres Strait Islander perspectives are diverse. Among the dominant discourses identified was a discourse that linked dance to broader social imperatives. Not only a cultural practice, Island Dance (Ailan Dans) emerges as an important aspect of postcolonial social movements amongst Torres Strait Islander people. Visual and performing arts such as dance are important in a postcolonial society and postcolonial curriculum in providing spaces to interrogate and engage with colonialist legacies, structures and representations. Dance is more than a practice or commodity in, for example, tourist performances: it is also a political product, in that fudigenous peoples can assert their rights through dance. Indigenous cultural practices are crucial as forums of Indigenous expression and 'voice', allowing people to resist dominant practices. The research suggests that Ailan Dans is important in community healing. Cultural practices such as dance also provide the possibility of interrogating stereotypical representations and images of Torres Strait Islander people. This thesis interrogates anthropological representations of Ailan Dans and suggests the need to consider the significance of Torres Strait Islander dance in the curriculum as an important, although contested, aspect of Torres Strait Islander resistance, affirmation, economic empowerment, communal wellbeing and artistic expression

Delayed gastric emptying and reduced postprandial small bowel water content of equicaloric whole meal bread versus rice meals in healthy subjects: novel MRI insights

BACKGROUND/OBJECTIVES: Postprandial bloating is a common symptom in patients with functional gastrointestinal (GI) diseases. Whole meal bread (WMB) often aggravates such symptoms though the mechanisms are unclear. We used magnetic resonance imaging (MRI) to monitor the intragastric fate of a WMB meal (11% bran) compared to a rice pudding (RP) meal. SUBJECTS/METHODS: 12 healthy volunteers completed this randomised crossover study. They fasted overnight and after an initial MRI scan consumed a glass of orange juice with a 2267 kJ WMB or an equicaloric RP meal. Subjects underwent serial MRI scans every 45 min up to 270 min to assess gastric volumes and small bowel water content and completed a GI symptom questionnaire. RESULTS: The MRI intragastric appearance of the two meals was markedly different. The WMB meal formed a homogeneous dark bolus with brighter liquid signal surrounding it. The RP meal separated into an upper, liquid layer and a lower particulate layer allowing more rapid emptying of the liquid compared to solid phase (sieving). The WMB meal had longer gastric half emptying times (132±8 min) compared to the RP meal (104±7 min), P<0.008. The WMB meal was associated with markedly reduced MRI-visible small bowel free mobile water content compared to the RP meal, P<0.0001. CONCLUSIONS: WMB bread forms a homogeneous bolus in the stomach which inhibits gastric sieving and hence empties slower than the equicaloric rice meal. These properties may explain why wheat causes postprandial bloating and could be exploited to design foods which prolong satiation

Cognitive and white-matter compartment models reveal selective relations 1 between corticospinal tract microstructure and simple reaction time

The speed of motor reaction to an external stimulus varies substantially between individuals and is slowed in ageing. However, the neuroanatomical origins of inter-individual variability in reaction time (RT) remain unclear. Here, we combined a cognitive model of RT and a biophysical compartment model of diffusion-weighted MRI (DWI) to characterize the relationship between RT and microstructure of the corticospinal tract (CST) and the optic radiation (OR), the primary motor output and visual input pathways associated with visual-motor responses. We fitted an accumulator model of RT to 46 female human participants' behavioral performance in a simple reaction time task. The non-decision time parameter (Ter) derived from the model was used to account for the latencies of stimulus encoding and action initiation. From multi-shell DWI data, we quantified tissue microstructure of the CST and OR with the neurite orientation dispersion and density imaging (NODDI) model as well as the conventional diffusion tensor imaging (DTI) model. Using novel skeletonization and segmentation approaches, we showed that DWI-based microstructure metrics varied substantially along CST and OR. The Ter of individual participants was negatively correlated with the NODDI measure of the neurite density in the bilateral superior CST. Further, we found no significant correlation between the microstructural measures and mean RT. Thus, our findings suggest a link between inter-individual differences in sensorimotor speed and selective microstructural properties in white matter tracts

Distinct abnormalities of small bowel and regional colonic volumes in subtypes of irritable bowel syndrome revealed by MRI

OBJECTIVES: Non-invasive biomarkers which identify different mechanisms of disease in subgroups of irritable bowel syndrome (IBS) could be valuable. Our aim was to seek useful magnetic resonance imaging (MRI) parameters that could distinguish each IBS subtypes. METHODS: 34 healthy volunteers (HV), 30 IBS with diarrhea (IBS-D), 16 IBS with constipation (IBS-C), and 11 IBS with mixed bowel habit (IBS-M) underwent whole-gut transit and small and large bowel volumes assessment with MRI scans from t=0 to t=360 min. Since the bowel frequency for IBS-M were similar to IBS-D, IBS-M and IBS-D were grouped together and labeled as IBS non-constipation group (IBS-nonC). RESULTS: Median (interquartile range): fasting small bowel water content in IBS-nonC was 21 (10–42), significantly less than HV at 44 ml (15–70), P<0.01 as was the postprandial area under the curve (AUC) P<0.01. The fasting transverse colon volumes in IBS-C were significantly larger at 253 (200–329) compared with HV, IBS-nonC whose values were 165 (117–255) and 198 (106–270) ml, respectively, P=0.02. Whole-gut transit time for IBS-C was prolonged at 69 (51–111), compared with HV at 34 (4–63) and IBS-D at 34 (17–78) h, P=0.03. Bloating score (VAS 0–10 cm) correlated with transverse colon volume at t=405 min, Spearman r=0.21, P=0.04. CONCLUSIONS: The constricted small bowel in IBS-nonC and the dilated transverse colon in IBS-C point to significant differences in underlying mechanisms of disease