213 research outputs found

    Anomalous dimensions at twist-3 in the sl(2) sector of N=4 SYM

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    We consider twist-3 operators in the sl(2) sector of N=4 SYM built out of three scalar fields with derivatives. We extract from the Bethe Ansatz equations of this sector the exact lowest anomalous dimension gamma(s) of scaling fields for several values of the operator spin s. We propose compact closed expressions for the spin dependence of gamma(s) up to the four loop level and show that they obey a simple new twist-3 transcendentality principle. As a check, we reproduce the four loop universal cusp anomalous dimension governing the logarithmic large spin limit of gamma(s).Comment: 26 pages, JHEP styl

    Follicular development of sows at weaning in relation to estimated breeding value for within-litter variation in piglet birth weight

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    In this study we aimed to identify possible causes of within-litter variation in piglet birth weight (birth weight variation) by studying follicular development of sows at weaning in relation to their estimated breeding value (EBV) for birth weight variation. In total, 29 multiparous sows (parity 3 to 5) were selected on their EBV for birth weight variation (SD in grams; High-EBV: 15.8±1.6, N=14 and Low-EBV: −24.7±1.5, N=15). The two groups of sows had similar litter sizes (15.7 v. 16.9). Within 24 h after parturition, piglets were cross-fostered to ensure 13 suckling piglets per sow. Sows weaned 12.8±1.0 and 12.7±1.0 piglets, respectively, at days 26.1±0.2 of lactation. Blood and ovaries were collected within 2 h after weaning. The right ovary was immediately frozen to assess average follicle size and percentage healthy follicles of the 15 largest follicles. The left ovary was used to assess the percentage morphologically healthy cumulus-oocyte complexes (COCs) of the 15 largest follicles. To assess the metabolic state of the sows, body condition and the circulating metabolic markers insulin, IGF1, non-esterified fatty acid, creatinine, leptin, urea and fibroblast growth factor 21 were analysed at weaning. No significant differences were found in any of the measured follicular or metabolic parameters between High-EBV and Low-EBV. A higher weight loss during lactation was related to a lower percentage healthy COCs (β= −0.65, P=0.02). Serum creatinine, a marker for protein breakdown, was negatively related to average follicle size (β= −0.60, P=0.05). Backfat loss during lactation was related to a higher backfat thickness at parturition and to a higher average follicle size (β=0.36, P<0.001) at weaning. In conclusion, we hypothesise that modern hybrid sows with more backfat at the start of lactation are able to mobilise more energy from backfat during lactation and could thereby spare protein reserves to support follicular development.</p

    Phase I trial of volasertib, a Polo-like kinase inhibitor, plus platinum agents in solid tumors: safety, pharmacokinetics and activity

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    Summary: Background This trial evaluated the maximum tolerated dose (MTD), safety, pharmacokinetics, and activity of volasertib, a selective Polo-like kinase 1 inhibitor that induces mitotic arrest and apoptosis, combined with cisplatin or carboplatin in patients with advanced/metastatic solid tumors (NCT00969761; 1230.6). Methods Sequential patient cohorts (3+3 dose-escalation design) received a single infusion of volasertib (100-350 mg) with cisplatin (60-100 mg/m2) or carboplatin (area under the concentration versus time curve [AUC]4-AUC6) on day 1 every 3 weeks for up to six cycles. Sixty-one patients received volasertib/cisplatin (n=30) or volasertib/carboplatin (n=31) for a median of 3.5 (range, 1-6) and 2.0 (range, 1-6) treatment cycles, respectively. Results The most common cycle 1 dose-limiting toxicities (DLTs) were thrombocytopenia, neutropenia and fatigue. MTDs (based on cycle 1 DLTs) were determined to be volasertib 300 mg plus cisplatin 100 mg/m2 and volasertib 300 mg plus carboplatin AUC6. Co-administration did not affect the pharmacokinetics of each drug. Partial responses were observed in two patients in each arm. Stable disease was achieved in 11 and six patients treated with volasertib/cisplatin and volasertib/carboplatin, respectively. Conclusions Volasertib plus cisplatin or carboplatin at full single-agent doses was generally manageable and demonstrated activity in heavily pretreated patients with advanced solid tumors.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Transparent Meta-Analysis of Prospective Memory and Aging

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    Prospective memory (ProM) refers to our ability to become aware of a previously formed plan at the right time and place. After two decades of research on prospective memory and aging, narrative reviews and summaries have arrived at widely different conclusions. One view is that prospective memory shows large age declines, larger than age declines on retrospective memory (RetM). Another view is that prospective memory is an exception to age declines and remains invariant across the adult lifespan. The present meta-analysis of over twenty years of research settles this controversy. It shows that prospective memory declines with aging and that the magnitude of age decline varies by prospective memory subdomain (vigilance, prospective memory proper, habitual prospective memory) as well as test setting (laboratory, natural). Moreover, this meta-analysis demonstrates that previous claims of no age declines in prospective memory are artifacts of methodological and conceptual issues afflicting prior research including widespread ceiling effects, low statistical power, age confounds, and failure to distinguish between various subdomains of prospective memory (e.g., vigilance and prospective memory proper)

    Un plan de l'air pour la Wallonie

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    Le Gouvernement Wallon a décrété l’année 2002 « année wallonne de la qualité de l’air ». Le lancement du « Projet de Plan wallon de l’Air à l’horizon 2010 » est au centre de cette manifestation. Son but est de mettre en place une politique intégrée de protection de l’air qui s’attaque aussi bien à la pollution locale qu’aux problèmes globaux de l’effet de serre et du trou dans la couche d’ozone. Grâce à une intense campagne médiatique et à un important effort de vulgarisation, l’enquête publique s’annonce déjà comme un succès

    Calcul symbolique non commutatif : analyse des constantes d'arbre de fouille

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    Working on some random variables, like additive parameters on multidimensional point quadtrees, or the number of maxima among a set of n points, independent and uniformly distributed in [0,1]^d makes appear some particular sequences, called multiple harmonic sums (MHS), extensions of classical harmonic numbers to compositions.Aiming at applying symbolic methods to study these random variables, we replace the use of compositions by encodings over different alphabets, and then call upon important results in the theory of combinatorics on words to apply them to our special sequences of MHS and to polylogarithms, derivative of generating functions of MHS. In convergent cases (respectively as z tends to 1 and as N tends to infinity) both converge to the same limit, called polyzêta. For divergent cases, the use of noncommutative generating series enables us to prove a theorem ``à l'Abel'', giving rise to a common limit. This theorem enables one to give an explicit form to generalized Euler constants associated to divergent MHS and so to get a very efficient algorithm to compute their asymptotic expansion.Finally, we suggest some applications of harmonic sums in the field of multidimensional data structure, for which our approach gives rise to exact computations, which can be then easily asymptotically evaluated.L'étude de certaines variables aléatoires, comme les paramètres additifs sur les arbres hyperquaternaires de points, ou encore le nombre de maxima au sein d'un ensemble de n points indépendants, et uniformément distribués dans [0,1]^d font apparaître des suites particulières, les sommes harmoniques multiples (SHM), extensions des nombres harmoniques classiques à des multi-indices.Nos travaux visant à appliquer des méthodes symboliques pour l'étude de ces variables aléatoires, nous remplaçons l'utilisation de multi-indices par des codages sur des alphabets distincts, et nous appuyons alors sur des résultats importants en combinatoire des mots pour les appliquer à nos suites de SHM, et aux fonctions polylogarithmes, qui sont des variantes des génératrices ordinaires des SHM. Dans les cas convergents, les deux objets convergent (respectivement lorsque z tend vers 1 et lorsque N tend vers l'infini) vers la même limite, appelée polyzêta. Pour les cas divergents, l'utilisation de séries génératrices non commutatives nous permet d'établir un théorème ``à l'Abel'', faisant apparaître une limite commune. Ce théorème permet de donner une forme explicite aux constantes d'Euler généralisées associées à des SHM divergentes et ainsi d'obtenir un algorithme très efficace pour calculer leur développement asymptotique.Finalement, nous proposons des applications des sommes harmoniques dans le domaine des structures de données multidimensionnelles, pour lesquelles notre approche donne naissance à des calculs exacts, qui peuvent par la suite être aisément évalués asymptotiquement

    The Interdisciplinary Study of Urban Bilingualism in Brussels - Witte,E, Beardsmore,Hb

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    Les grandes lignes du plan wallon de l'air

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    Woningautomatisatie via een PLC-systeem

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    Gewijzigde gebruikerseisen inzake comfort, vei ligheid, bevei liging en energiemanagement hebben tot gevolg dat klassieke woninginstallaties in een hedendaagse woning nauwelijks aan de verschil lende noden kunnen blijven beantwoorden. Het automatiseren van woonfunct ies lijkt een voor de hand liggende oplossing voor deze uitbreiding van het eisenpakket. Natuurlijk rijst dan de vraag waarom woningautomatisatiesystemen niet tot het gemiddelde huishouden zijn doorgedrongen? Blijven hoge complexiteit of economische aspecten een te hoge drempel voor de potentiële gebruiker? Deze thesis beloopt de weg van woningautomatisatiesystemen, gebaseerd op power line communicatie via het 230V laagspanningsnet. Het grootste voordeel van deze vorm van communiceren is het gebruik van een bestaande structuur. Men maakt immers gebruik van een ontwikkelde infrastructuur die reeds in elke woning aanwezig is. De thesis start met een algemene introductie tot woningautomatisatie en de benodigde technische apparatuur. Vervolgens wordt er toegespitst op power line communicatie met de bedoeling kennis op te doen in hoe een elektriciteitsnet kan fungeren als een communicatiekanaal. De kanaalkarakteristieken worden bestudeerd via metingen, waarbij de belangrijkste parameters die een rol spelen in de verandering van de kanaalkwaliteit worden onderzocht. Metingen van het ruisniveau en de kanaalweerstand tot 16 MHz zijn opgenomen. Het power line communicatiekanaal kan aan de hand van gedane metingen worden gedefinieerd als functie van een tijdsvariabele, frequentieafhankelijke signaal-ruisniveau ratio over de gebruikte communicatiebandwijdte. Het effect van het ruisniveau wordt geïllustreerd en we gaan op zoek naar een robuuste, incomplexe modulatiemethode die in staat is om met een onbekende fase en kanaalweerstand om te gaan. Uiteraard vereenvoudigt dit de implementatie van de ontvanger. Tenslotte wordt een automatisatiesysteem uitgewerkt voor een effectief praktijkvoorbeeld, waarbij het In One by Legrand systeem wordt aangewend. Het gebruik van de power line communicatie leidt tot een zeer flexibele oplossing die op elk moment kan worden opgewaardeerd en geadapteerd naar toekomstige noden
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