The impact of air pollution on hospital admissions: Evidence from Italy

In this paper we study the impact of air pollution on hospital admissions for chronic obstructive pulmonary disease for 103 Italian provinces, over the period from 2004 to 2009. We use information on annual mean concentrations of carbon monoxide, nitrogen dioxide, particulate matter, and ozone measured at monitoring station level to build province-level indicators of pollution. Hence, we estimate a regression model for hospital admissions, where we allow our aggregate measures of pollution to be subject to measurement error and correlated with the error term. We also adopt standard errors for estimates that are robust to serial and spatial correlation in the error term, to allow for temporal persistence and geographical concentration of unobservable risk factors.We find that higher levels of particulate matter are associated with higher levels of hospitalisation for children, while ozone plays an important role in explaining hospital admissions of the elderly. Other factors that appear to have an effect on hospital admissions for chronic obstructive pulmonary disease are precipitation and provincial unemployment rate

Long and very-long-chain ceramides correlate with a more aggressive behavior in skull base chordoma patients

Background: Skull base chordomas are rare tumors arising from notochord. Sphingolipids analysis is a promising approach in molecular oncology, and it has never been applied in chordomas. Our aim is to investigate chordoma behavior and the role of ceramides. Methods: Ceramides were extracted and evaluated by liquid chromatography and mass spectrometry in a cohort of patients with a skull base chordoma. Clinical data were also collected and correlated with ceramide levels. Linear regression and correlation analyses were conducted. Results: Analyzing the association between ceramides level and MIB-1, total ceramides and dihydroceramides showed a strong association (r = 0.7257 and r = 0.6733, respectively) with MIB-1 staining (p = 0.0033 and p = 0.0083, respectively). Among the single ceramide species, Cer C24:1 (r = 0.8814, p <= 0.0001), DHCer C24:1 (r = 0.8429, p = 0.0002) and DHCer C18:0 (r = 0.9426, p <= 0.0001) showed a significant correlation with MIB-1. Conclusion: Our lipid analysis showed ceramides to be promising tumoral biomarkers in skull base chordomas. Long- and very-long-chain ceramides, such as Cer C24:1 and DHCer C24:1, may be related to a prolonged tumor survival and aggressiveness, and the understanding of their effective biological role will hopefully shed light on the mechanisms of chordoma radio-resistance, tendency to recur, and use of agents targeting ceramide metabolism

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Conto finanziario della gestione della Corte dei Conti per l'anno 1997

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca della Camera dei Deputati, Via del Seminario, 76, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Decisione e relazione della Corte dei Conti sul rendiconto generale dello Stato per l'esercizio finanziario 1999

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca della Camera dei Deputati, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Conto finanziario della gestione della Corte dei Conti per l'anno 1999

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca della Camera dei Deputati, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Referto sull'indagine intersettoriale sui lavori pubblici : programma di controllo 2000

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca della Camera dei Deputati, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Decisione della Corte dei Conti sul rendiconto generale dello Stato per l'esercizio finanziario 1998 e conti allegati

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca della Camera dei Deputati, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Decisione e relazione della Corte dei Conti sul rendiconto generale dello Stato per l'esercizio finanziario 1997

4 v. in 6Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca della Camera dei Deputati, Via del Seminario, 76, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Restoration works in the city of Venice. Geotechnical aspects.

In restoration and consolidation design the knowledge of the interaction between soil and structure plays a major role in structural behaviour over time. This aspect is particularly important when dealing with the city of Venice, where the buildings are generally characterized by important total and differential settlements as a result of stratigraphic variability and the pressure induced by different types of foundation. The interaction between the construction and foundation as they develop over time must take the building\u2019s history into consideration making full use of archive sources and on-site inspections. In this paper a general outline of the subsoil is presented, based on results from geotechnical investigations carried out in different areas of the city (sestrieri), where the shallow layers consisting of soft medium silty clays and peaty soil alternate between deeper layers of compact medium clay and fine sand. An attempted historical reconstruction of consolidation settlements relating to St. Mark\u2019s bell tower will be presented, as an example of soil structure interaction within the framework of critical state soil mechanics