Iceland, an Open-Air Museum for Geoheritage and Earth Science Communication Purposes

Iceland is one of the most recognizable and iconic places on Earth, o\ufb00ering an unparalleled chance to admire the most powerful natural phenomena related to the combination of geodynamic, tectonic and magmatic forces, such as active rifting, volcanic eruptions and subvolcanic intrusions. We have identi\ufb01ed and selected 25 geosites from the Sn\ue6fellsnes Peninsula and the Northern Volcanic Zone, areas where most of the above phenomena can be admired as they unfold before the viewers\u2019 eyes. We have qualitatively assessed the selected volcano\u2013tectonic geosites by applying a set of criteria derived from previous studies and illustrated them through \ufb01eld photographs, unmanned aerial vehicle (UAV)-captured images and 3-D models. Finally, we have discussed and compared the di\ufb00erent options and advantages provided by such visualization techniques and proposed a novel, cutting-edge approach to geoheritage promotion and popularization, based on interactive, navigable Virtual Outcrops made available online

An international, prospective observational study on traumatic brain injury epidemiology study protocol: GEO-TBI: Incidence [version 2; peer review: 2 approved]

Background The epidemiology of traumatic brain injury (TBI) is unclear – it is estimated to affect 27–69 million individuals yearly with the bulk of the TBI burden in low-to-middle income countries (LMICs). Research has highlighted significant between-hospital variability in TBI outcomes following emergency surgery, but the overall incidence and epidemiology of TBI remains unclear. To address this need, we established the Global Epidemiology and Outcomes following Traumatic Brain Injury (GEO-TBI) registry, enabling recording of all TBI cases requiring admission irrespective of surgical treatment. Objective The GEO-TBI: Incidence study aims to describe TBI epidemiology and outcomes according to development indices, and to highlight best practices to facilitate further comparative research. Design Multi-centre, international, registry-based, prospective cohort study. Subjects Any unit managing TBI and participating in the GEO-TBI registry will be eligible to join the study. Each unit will select a 90-day study period. All TBI patients meeting the registry inclusion criteria (neurosurgical/ICU admission or neurosurgical operation) during the selected study period will be included in the GEO-TBI: Incidence. Methods All units will form a study team, that will gain local approval, identify eligible patients and input data. Data will be collected via the secure registry platform and validated after collection. Identifiers may be collected if required for local utility in accordance with the GEO-TBI protocol. Data Data related to initial presentation, interventions and short-term outcomes will be collected in line with the GEO-TBI core dataset, developed following consensus from an iterative survey and feedback process. Patient demographics, injury details, timing and nature of interventions and post-injury care will be collected alongside associated complications. The primary outcome measures for the study will be the Glasgow Outcome at Discharge Scale (GODS) and 14-day mortality. Secondary outcome measures will be mortality and extended Glasgow Outcome Scale (GOSE) at the most recent follow-up timepoint

How do cardiologists select patients for dual antiplatelet therapy continuation beyond 1 year after a myocardial infarction? Insights from the EYESHOT Post-MI Study

Background: Current guidelines suggest to consider dual antiplatelet therapy (DAPT) continuation for longer than 12 months in selected patients with myocardial infarction (MI). Hypothesis: We sought to assess the criteria used by cardiologists in daily practice to select patients with a history of MI eligible for DAPT continuation beyond 1 year. Methods: We analyzed data from the EYESHOT Post-MI, a prospective, observational, nationwide study aimed to evaluate the management of patients presenting to cardiologists 1 to 3 years from the last MI event. Results: Out of the 1633 post-MI patients enrolled in the study between March and December 2017, 557 (34.1%) were on DAPT at the time of enrolment, and 450 (27.6%) were prescribed DAPT after cardiologist assessment. At multivariate analyses, a percutaneous coronary intervention (PCI) with multiple stents and the presence of peripheral artery disease (PAD) resulted as independent predictors of DAPT continuation, while atrial fibrillation was the only independent predictor of DAPT interruption for patients both at the second and the third year from MI at enrolment and the time of discharge/end of the visit. Conclusions: Risk scores recommended by current guidelines for guiding decisions on DAPT duration are underused and misused in clinical practice. A PCI with multiple stents and a history of PAD resulted as the clinical variables more frequently associated with DAPT continuation beyond 1 year from the index MI

Guida pratica per guide geologiche

Questa guida, nelle intenzioni, si propone di aiutare le Guide geologiche a progettare geo-itinerari e a svilupparne la conduzione. Sono trattati tanto gli aspetti prettamente geologici, quanto le modalit\ue0 con le quali una guida deve interfacciarsi con gli escursionisti. Sono inoltre presi in considerazione i materiali da utilizzare durante i percorsi geo-escursionistici e le strategie utili a catturare la costante attenzione dei partecipanti. Concludono la trattazione due casi concreti di itinerari (entrambi organizzati lungo la Valle del But) che esemplificano quanto appreso nella prima parte del testo