Local Interstellar Medium Kinematics towards the Southern Coalsack and Chamaeleon-Musca dark clouds

The results of a spectroscopic programme aiming to investigate the kinematics of the local interstellar medium components towards the Southern Coalsack and Chamaeleon-Musca dark clouds are presented. The analysis is based upon high-resolution (R ~ 60,000) spectra of the insterstellar NaI D absorption lines towards 63 B-type stars (d < 500 pc) selected to cover these clouds and the connecting area defined by the Galactic coordinates: 308 > l > 294 and -22 < b < 5. The radial velocities, column densities, velocity dispersions, colour excess and photometric distances to the stars are used to understand the kinematics and distribution of the interstellar cloud components. The analysis indicates that the interstellar gas is distributed in two extended sheet-like structures permeating the whole area, one at d < 60 pc and another around 120-150 pc from the Sun. The dust and gas feature around 120-150 pc seem to be part of an extended large scale feature of similar kinematic properties, supposedly identified with the interaction zone of the Local and Loop I bubbles.Comment: 19 pages, accepted for MNRA

High-velocity collimated outflows in planetary nebulae: NGC 6337, He 2-186, and K 4-47

We have obtained narrow-band images and high-resolution spectra of the planetary nebulae NGC 6337, He 2-186, and K 4-47, with the aim of investigating the relation between their main morphological components and several low-ionization features present in these nebulae. The data suggest that NGC 6337 is a bipolar PN seen almost pole on, with polar velocities higher than 200 km/s. The bright inner ring of the nebula is interpreted to be the "equatorial" density enhancement. It contains a number of low-ionization knots and outward tails that we ascribe to dynamical instabilities leading to fragmentation of the ring or transient density enhancements due to the interaction of the ionization front with previous density fluctuations in the ISM. The lobes show a pronounced point-symmetric morphology and two peculiar low-ionization filaments whose nature remains unclear. The most notable characteristic of He 2-186 is the presence of two high-velocity (higher than 135 km/s) knots from which an S-shaped lane of emission departs toward the central star. K 4-47 is composed of a compact core and two high-velocity, low-ionization blobs. We interpret the substantial broadening of line emission from the blobs as a signature of bow shocks, and using the modeling of Hartigan, Raymond, & Hartman (1987), we derive a shock velocity of 150 km/s and a mild inclination of the outflow on the plane of the sky. We discuss possible scenarios for the formation of these nebulae and their low-ionization features. In particular, the morphology of K 4-47 hardly fits into any of the usually adopted mass-loss geometries for single AGB stars. Finally, we discuss the possibility that point-symmetric morphologies in the lobes of NGC 6337 and the knots of He 2-186 are the result of precessing outflows from the central stars.Comment: 16 pages plus 7 figures, ApJ accepted. Also available at http://www.iac.es/publicaciones/preprints.htm

Cystic fibrosis transmembrane conductance regulator (CFTR): closed and open state channel models.

The cystic fibrosis transmembrane conductance regulator (CFTR) is a member of the ATP binding cassette (ABC) transporter superfamily. CFTR controls the flow of anions through the apical membrane of epithelia. Dysfunctional CFTR causes the common lethal genetic disease cystic fibrosis. Transitions between open and closed states of CFTR are regulated by ATP binding and hydrolysis on the cystosolic nucleotide binding domains (NBDs), which are coupled with the transmembrane domains (TMDs) forming the pathway for anion permeation. Lack of structural data hampers a global understanding of CFTR, and thus the development of rational approaches directly targeting defective CFTR. In this work, we explored possible conformational states of the CFTR gating cycle by means of homology modeling. As templates, we used structures of homologous ABC transporters, namely TM287- 288, ABC-B10, McjD and Sav1866. In the light of published experimental results, structural analysis of the transmembrane cavity suggests that the TM287-288-based CFTR model could correspond to a commonly occupied closed state, while the McjD-based model could represent an open state. The models capture the important role played by Phe337 as a filter/gating residue and provide structural information on the conformational transition from closed to open channel

A three-dimensional view of the remnant of Nova Persei 1901 (GK Per)

We present a kinematical study of the optical ejecta of GK Per. It is based on proper motions measurements of 282 knots from ~20 images spanning 25 years. Doppler-shifts are also computed for 217 knots. The combination of proper motions and radial velocities allows a unique 3-D view of the ejecta to be obtained. The main results are: (1) the outflow is a thick shell in which knots expand with a significant range of velocities, mostly between 600 and 1000 km/s; (2) kinematical ages indicate that knots have suffered only a modest deceleration since their ejection a century ago; (3) no evidence for anisotropy in the expansion rate is found; (4) velocity vectors are generally aligned along the radial direction but a symmetric pattern of non-radial velocities is also observed at specific directions; (5) the total Halpha+[NII] flux has been linearly decreasing at a rate of 2.6 % per year in the last decade. The Eastern nebular side is fading at a slower rate than the Western one. Some of the knots displayed a rapid change of brightness during the 2004-2011 period. Over a longer timescale, a progressive circularization and homogenization of the nebula is taking place; (6) a kinematic distance of 400+-30 pc is determined. These results raise some problems to the previous interpretations of the evolution of GK Per. In particular, the idea of a strong interaction of the outflow with the surrounding medium in the Southwest quadrant is not supported by our data.Comment: Accepted for publication in The Astrophysical Journal (19 pages, 17 figures). Higher resolution version of this article (2.5 MB) is available at http://www.aai.ee/~sinope/ApJ89291_liimets.pd

Knots in the outer shells of the planetary nebulae IC 2553 and NGC 5882

We present images and high-resolution spectra of the planetary nebulae IC 2553 and NGC 5882. Spatio-kinematic modeling of the nebulae shows that they are composed of a markedly elongated inner shell, and of a less aspherical outer shell expanding at a considerably higher velocity than the inner one. Embedded in the outer shells of both nebulae are found several low-ionization knots. In IC 2553, the knots show a point-symmetric distribution with respect to the central star: one possible explanation for their formation is that they are the survivors of pre-existing point-symmetric condensations in the AGB wind, a fact which would imply a quite peculiar mass-loss geometry from the giant progenitor. In the case of NGC 5882, the lack of symmetry in the distribution of the observed low-ionization structures makes it possible that they are the result of in situ instabilities.Comment: 20 pages including 1 table and 6 figures. ApJ accepted. Also available at http://andromeda.roque.ing.iac.es/~sanchez/ingpub/index2000.htm

The large-scale ionised outflow of CH Cygni

HST and ground-based [OII} and [NII] images obtained from 1996 to 1999 reveal the existence of a ionised optical nebula around the symbiotic binary CH Cyg extending out to 5000 A.U. from the central stars. The observed velocity range of the nebula, derived from long-slit echelle spectra, is of 130 km/s. In spite of its complex appearence, the velocity data show that the basic morphology of the inner regions of the optical nebula is that of a bipolar (or conical) outflow extending nearly along the plane of the sky out to some 2000 A.U. from the centre. Even if the extension of this bipolar outflow and its position angle are consistent with those of the radio jet produced in 1984 (extrapolated to the time of our optical imagery), no obvious counterpart is visible of the original, dense radio bullets ejected by the system. We speculate that the optical bipolar outflow might be the remannt of the interaction of the bullets with a relatively dense circumstellar medium.Comment: 8 text pages + 3 figures (jpeg). ApJ in press. For a full PostScript version with figures inline see ftp://ftp.ll.iac.es/pub/research/preprints/PP252001.ps.g