Caracterización de la diversidad genética de uchuva (physalis peruviana l.) En Boyacá

Cape gooseberry, Physalis peruviana L. is a tropical fruit tree native to the Andean region, presenting primary and secondary metabolites that confer antioxidant, anti-inflammatory and anticancer properties. It is currently the second export fruit in Colombia, with Boyacá being one of the departments that contributes most to national production. Therefore, the objective of this research was to characterize the genetic diversity of Cape gooseberry in the Department of Boyacá. A collection of 15 wild materials from P. Peruviana was carried out in the municipalities of Paipa, Combita, Tuta, Sotaquirá, Santa Rosa de Viterbo and Tunja and were characterized with seven RAMs microsatellite markers. The analysis by the Nei-Li coefficient at a similarity level of 0,65 differentiated the population in three groups according to the site of origin of the materials. The average Heterocigosidad value was 0,27, which is considered low compared to other genetic diversity studies. The analysis of Molecular variance (AMOVA) and the Fst show the existence of genetic variability at the intraspecific level which should be retained and used in the genetic improvement that allows the obtaining of adapted materials, with characteristics agronomic, nutritional and medicinal of high quality. La uchuva, Physalis peruviana L. es un frutal tropical nativo de la región Andina, que presenta metabolitos primarios y secundarios que le confiere propiedades antioxidantes, anti-inflamatorias y anticancerígenas. Actualmente es el segundo frutal de exportación en Colombia, siendo Boyacá uno de los departamentos que más contribuye a la producción nacional. Por lo cual el objetivo de esta investigación fue caracterizar la diversidad genética de la uchuva en el departamento de Boyacá. Se realizó una colecta de 15 materiales silvestres de P. peruviana en los municipios de Paipa, Combita, Tuta, Sotaquirá, Santa Rosa de Viterbo y Tunja y fueron caracterizados con siete marcadores microsatélites RAMs. El análisis mediante el coeficiente de Nei-Li a un nivel de similitud de 0,65 diferenció a la población en tres grupos de acuerdo al sitio de procedencia de los materiales. El valor de heterocigosidad promedio fue de 0,27 el cual se considera bajo en comparación con otros estudios de diversidad genética. El Análisis de Varianza Molecular (AMOVA) y el Fst muestran la existencia de variabilidad genética a nivel intraespecífico la cual debe ser conservada y aprovechada en el mejoramiento genético que permita la obtención de materiales adaptados, con características agronómicas, nutricionales y medicinales de alta calidad

Herramienta para la implantación hardware de controladores sobre FPGAs

Barcelona, 12-14 de septiembre de 2001Deseamos agradecerle al departamento de electrónica, tecnología de computadoras y proyectos su apoyo técnico en la realización de este proyecto. Además deseamos agradecer al CEDETEL su apoyo económico

Desarrollo de un equipo didáctico para prácticas en asignaturas de control e identificación

En este artículo se presentan los detalles de un equipo didáctico desarrollado por los autores bajo las especificaciones dadas por los profesores del departamento DISA de la UPCT. Se ha tratado de crear un equipo que permita realizar el más amplio abanico de prácticas en las asignaturas de regulación y control de sistemas de este departamento. Además se hizo un esfuerzo especial en conseguir un equipo sencillo de manejo, robusto, fiable, seguro, versátil y de arquitectura abierta, características que a nuestro entender hay que cumplir para conseguir un buen equipo didáctico. En este articulo se muestran los detalles constructivos así como sus posibilidades como equipo de prácticas en las asignaturas de automática.Los autores desean mostrar su agradecimiento al Departamento de Ingeniería de Sistemas y Automática de la UPCT por su apoyo y apuesta por una iniciativa de este tipo

Aplicación de comités de expertos en el modelado del comportamiento humano en situaciones de distorsión visuo-motora

En este trabajo se presenta una aplicación de las arquitecturas neuronales basadas en comités de expertos en donde dan una buena solución en un problema de modelado del comportamiento visuomotor humano. La intención de este artículo ha sido la de mostrar la validez de las redes en comités sobre una aplicación de modelado de sistemas biológicos. Se trata por tanto de mostrar un modelo del comportamiento psicofísico humano, es decir, del comportamiento de las arquitecturas neuronales biológicas mediante redes neuronales artificiales en donde las redes en comité de expertos forman parte de la arquitectura global del modelo

Hardware implementation of a controller based on neurobiological adaptive models of the human motor-control system

In this work, a neural structure has been implemented into a device based on the new trends in hardware integration, for motor-control In multisensorial anthropomorphic robotic systems. This implementation gives a solution to the problem of physic integration of biologically Inspired control hierarchies in a robotic head-arm installation for robotic reaching tasks. The complete architecture has been implemented on an electronic board connected to a PC computer through a PCI interface. The hardware structure consists of two blocks: one for the working phase of the system, and the other for the learning and supervision phase of the system. These two blocks have been implemented with different technologies based on DSP processors and FPGAs. The algorithms implemented on DSPs have the function of updating the neural network on the FPGA, supervising the working of the algorithm implemented on FPGA and introducing corrections when the neural network produces results with little errors. The neural network has been implemented on FPGA and implements spatial-motor transformations of the robotic platform. It is programmed and updated by the supervisor implemented on a DSP processo

Foetal Immune Response Activation and High Replication Rate during Generation of Classical Swine Fever Congenital Infection

Classical swine fever virus (CSFV) induces trans-placental transmission and congenital viral persistence; however, the available information is not updated. Three groups of sows were infected at mid-gestation with either a high, moderate or low virulence CSFV strains. Foetuses from sows infected with high or low virulence strain were obtained before delivery and piglets from sows infected with the moderate virulence strain were studied for 32 days after birth. The low virulence strain generated lower CSFV RNA load and the lowest proportion of trans-placental transmission. Severe lesions and mummifications were observed in foetuses infected with the high virulence strain. Sows infected with the moderately virulence strain showed stillbirths and mummifications, one of them delivered live piglets, all CSFV persistently infected. Efficient trans-placental transmission was detected in sows infected with the high and moderate virulence strain. The trans-placental transmission occurred before the onset of antibody response, which started at 14 days after infection in these sows and was influenced by replication efficacy of the infecting strain. Fast and solid immunity after sow vaccination is required for prevention of congenital viral persistence. An increase in the CD8+ T-cell subset and IFN-alpha response was found in viremic foetuses, or in those that showed higher viral replication in tissue, showing the CSFV recognition capacity by the foetal immune system after trans-placental infection.info:eu-repo/semantics/publishedVersio

Acute myelocytic leukemia in pregnancy case report and literature review: a case report

Leukemia is a rare entity in pregnant women, when it occurs it is usually of myeloid origin and acute course, its diagnosis and management remains a challenge because of the limited availability of information resources due to the low frequency of this pathology, the management decision will be carried out by a multidisciplinary team that includes obstetricians, hematologists, psychologists, involving ethical issues always seeking to improve the maternal and fetal prognosis and never forgetting the wishes of the patient and her family. We present the case of a woman in the fourth decade of life, with pregnancy in the third trimester in which acute myeloid leukemia was diagnosed and where it was decided by a consensus of specialists in hematology, gynecology and pediatrics, to prolong the pregnancy until 32 weeks and then start chemotherapy

Abrogation of the RNase activity of Erns in a low virulence classical swine fever virus enhances the humoral immune response and reduces virulence, transmissibility, and persistence in pigs

The prevalence of low virulence classical swine fever virus (CSFV) strains makes viral eradication difficult in endemic countries. However, the determinants for natural CSFV attenuation and persistence in the field remain unidentified. The aim of the present study was to assess the role of the RNase activity of CSFV Erns in pathogenesis, immune response, persistent infection, and viral transmission in pigs. To this end, a functional cDNA clone pPdR-H30K-36U with an Erns lacking RNase activity was constructed based on the low virulence CSFV field isolate Pinar de Rio (PdR). Eighteen 5-day-old piglets were infected with vPdR-H30K-36U. Nine piglets were introduced as contacts. The vPdR-H30K-36U virus was attenuated in piglets compared to the parental vPdR-36U. Only RNA traces were detected in sera and body secretions and no virus was isolated from tonsils, showing that RNase inactivation may reduce CSFV persistence and transmissibility. The vPdR-H30K-36U mutant strongly activated the interferon-α (IFN-α) production in plasmacytoid dendritic cells, while in vivo, the IFN-α response was variable, from moderate to undetectable depending on the animal. This suggests a role of the CSFV Erns RNase activity in the regulation of innate immune responses. Infection with vPdR-H30K-36U resulted in higher antibody levels against the E2 and Erns glycoproteins and in enhanced neutralizing antibody responses when compared with vPdR-36U. These results pave the way toward a better understanding of viral attenuation mechanisms of CSFV in pigs. In addition, they provide novel insights relevant for the development of DIVA vaccines in combination with diagnostic assays for efficient CSF control.info:eu-repo/semantics/publishedVersio

Más Allá de la Piel : Propuesta audiovisual de extensión social de la Universidad Autónoma del Caribe y la fundación África Mía.

Más Allá de la Piel son tres piezas audiovisuales formato documental etnográfico. En cada uno de ellos, jóvenes participantes narran desde su experiencia personal, sus vivencias en el transcurso del proceso de capacitación. Expresan como ven el proceso y visualizan el futuro. Igualmente, los actores institucionales vinculados a esta campaña, quienes manifiestan los objetivos, metas, impactos y dinámicas que mantiene activo dicho proceso de gestión cultural y social. Además, se explica cómo es el proceso de adhesión y apoyo a esta campaña e invitar a los sectores productivos a formar parte de esta obra de gran impacto social