Climate-smart solutions for Mali: Findings from implementing the Climate-Smart Agriculture Prioritization Framework

This info note summarizes findings of a pilot project aiming to develop a participatory framework to prioritize CSA practices and interventions to guide CSA investments in Mali. It was undertaken by researchers from the Malian Association of Awareness to Sustainable Development (AMEDD) and the International Center Tropical Agriculture (CIAT) as part of the CGIAR Research Program on Climate Change, Agriculture, and Food Security (CCAFS). Implementation was led by the Agency of Environment and Sustainable Development (AEDD) on behalf of the National Science-Policy dialogue platforms on Climate Change, Agriculture and Food Security (CCASA). Supported by the West Africa Regional Program, this research is part of a multi-region Prioritization project funded by CCAFS Flagship 1 on Climate-Smart Agricultural Practices

Accounting for inventory data and methodological choice uncertainty in a comparative life cycle assessment: the case of integrated multi-trophic aquaculture in an offshore Mediterranean enterprise

Purpose: Integrated multi-trophic aquaculture (IMTA), growing different species in the same space, is a technology that may help manage the environmental impacts of coastal aquaculture. Nutrient discharges to seawater from monoculture aquaculture are conceptually minimized in IMTA, while expanding the farm economic base. In this study, we investigate the environmental trade-offs for a small-to-medium enterprise (SME) considering a shift from monoculture towards IMTA production of marine fish. Methods: A comparative life cycle assessment (LCA), including uncertainty analysis, was implemented for an aquaculture SME in Italy. Quantification and simultaneous propagation of uncertainty of inventory data and uncertainty due to the choice of allocation method were combined with dependent sampling to account for relative uncertainties and statistical testing and interpretation to understand the uncertainty analysis results. Monte Carlo simulations were used as a propagation method. The environmental impacts per kilo of fish produced in monoculture and in IMTA were compared. Twelve impact categories were considered. The comparison is first made excluding uncertainty (deterministic LCA) and then accounting for uncertainties. Results and discussion: Deterministic LCA results evidence marginal differences between the impacts of IMTA and monoculture fish production. IMTA performs better on all impacts studied. However, statistical testing and interpretation of the uncertainty analysis results showed that only mean impacts for climate change are significantly different for both productive systems, favoring IMTA. For the case study, technical variables such as scales of production of the species from different trophic levels, their integration (space and time), and the choice of species determine the trade-offs. Also, LCA methodological choices such as that for an allocation method and the treatment of relative uncertainties were determinant in the comparison of environmental trade-offs. Conclusions: The case study showed that environmental trade-offs between monoculture and IMTA fish production depend on technical variables and methodological choices. The combination of statistical methods to quantify, propagate, and interpret uncertainty was successfully tested. This approach supports more robust environmental trade-off assessments between alternatives in LCAs with uncertainty analysis by adding information on the significance of results. It was difficult to establish whether IMTA does bring benefits given the scales of production in the case study. We recommend that the methodology defined here is applied to fully industrialized IMTA systems or bay-scale environments, to provide more robust conclusions about the environmental benefits of this aquaculture type in Europe

Exenatide twice-daily does not affect renal function or albuminuria compared to titrated insulin glargine in patients with type 2 diabetes mellitus : A post-hoc analysis of a 52-week randomised trial

Aims: To compare the effects of long-term treatment with the GLP-1RA exenatide twicedaily versus titrated insulin glargine (iGlar) on renal function and albuminuria in type 2 diabetes (T2DM) patients. Methods: We post-hoc evaluated renal outcome-data of 54 overweight T2DM patients (mean +/- SD age 60 +/- 8 years, HbA1c 7.5 +/- 0.9%, eGFR 86 +/- 16 mL/min/1.73m(2), median [IQR] urinary albumin-to-creatinine-ratio (UACR) 0.75 [0.44-1.29] mg/mmol) randomised to exenatide 10 mg twice-daily or titrated iGlar on-top-of metformin for 52-weeks. Renal efficacy endpoints were change in creatinine clearance (CrCl) and albuminuria (urinary albuminexcretion [UAE] and UACR) based on 24-h urines, collected at baseline and Week-52. eGFR and exploratory endpoints were collected throughout the intervention-period, and after a 4-week wash-out. Results: HbA1c-reductions were similar with exenatide (mean +/- SEM -0.80 +/- 0.10%) and iGlar (-0.79 +/- 0.14%; treatment-difference 0.02%; 95% CI - 0.31 to 0.42%). Change from baseline to Week-52 in CrCl, UAE or UACR did not statistically differ; only iGlar reduced albuminuria (P <0.05; within-group). eGFR decreased from baseline to Week-4 with exenatide (-3.9 +/- 2.1 mL/min/1.73 m(2); P = 0.069) and iGlar (-2.7 +/- 1.2 mL/min/1.73 m(2); P = 0.034), without treatment-differences in ensuing trajectory. Exenatide versus iGlar reduced bodyweight (-5.4 kg; 2.9-7.9; P <0.001), but did not affect blood pressure, lipids or plasma uric acid. Conclusions: Among T2DM patients without overt nephropathy, one-year treatment with exenatide twice-daily does not affect renal function-decline or onset/progression of albuminuria compared to titrated iGlar. (C) 2019 Elsevier B.V. All rights reserved.Peer reviewe

How to involve cancer patients at the end of life as co-researchers

The importance of user involvement in the organisation and delivery of health services and the conduct of research has increased over recent decades. Involving people at the end of life in research remains an under-developed area of research activity. The Macmillan Listening Study, a UK-wide study exploring research views and priorities of people affected by cancer, adopted a participatory research approach. Patients and carers, including two participants receiving palliative care services, collaborated in all aspects of the study as coresearchers. In this paper, we discuss the experience of working with co-researchers to collect data from two hospices. We will discuss practical, ethical and methodological challenges, including specific training needs and the emotional demands of conducting the research. Recommendations are made to facilitate successful collaboration with palliative care service users in end of life research. Palliative Medicine 2006; 20: 821 Á82

Public understanding in Great Britain of ocean acidification

Public engagement with climate change is critical for maintaining the impetus for meaningful emissions cuts. Ocean acidification (OA) is increasingly recognized by marine scientists as an important, but often overlooked, consequence of anthropogenic emissions1, 2. Although substantial evidence now exists concerning people’s understanding of climate change more generally3, very little is known about public perceptions of OA. Here, for the first time, we characterize in detail people’s understanding of this topic using survey data obtained in Great Britain (n = 2,501) during 2013 and 2014. We draw on theories of risk perception and consider how personal values influence attitudes towards OA. We find that public awareness of OA is very low compared to that of climate change, and was unaffected by the publication of the IPCC Fifth Assessment Report. Using an experimental approach, we show that providing basic information can heighten concern about OA, however, we find that attitude polarization along value-based lines may occur if the topic is explicitly associated with climate change. We discuss the implications of our findings for public engagement with OA, and the importance of learning lessons from communications research relating to climate change

Context-Aware User Authentication – Supporting Proximity-Based Login in Pervasive Computing

Abstract. This paper explores computer security in pervasive computing with focus on user authentication. We present the concept of Proximity-Based User Authentication, as a usability-wise ideal for UbiComp systems. We present a context-aware user authentication protocol, which (1) uses a JavaCard for identi-fication and cryptographic calculations, (2) uses a context-awareness system for verifying the user’s location, and (3) implements a security fall-back strategy. We analyze the security of this protocol and discuss the tradeoff between usabil-ity and security. We also present our current implementation of the protocol and discuss future work.