14 research outputs found

    The long term effects of sports concussion on retired Australian football players: a study using Transranial Magnetic Stimulation

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    This study investigated corticomotor excitability and inhibition, cognitive functioning, and fine motor dexterity in retired elite and amateur Australian football (AF) players who had sustained concussions during their playing careers. Forty male AF players who played at the elite level (n=20; mean age 49.7±5.7 years) or amateur level (n=20; mean age 48.4±6.9 years), and had sustained on average 3.2 concussions 21.9 years previously, were compared with 20 healthy age-matched male controls (mean age 47.56±6.85 years). All participants completed assessments of fine dexterity, visuomotor reaction time, spatial working memory (SWM), and associative learning (AL). Transcranial magnetic stimulation (TMS) was used to measure corticospinal excitability: stimulus-response (SR) curves and motor evoked potential (MEP) 125% of active motor threshold (aMT); and intracortical inhibition: cortical silent period (cSP), short-interval intracortical inhibition (SICI), and long-interval intracortical inhibition (LICI). Healthy participants performed better in dexterity (p=0.003), reaction (p=0.003), and movement time (p=0.037) than did both AF groups. Differences between AF groups were found in AL (p=0.027) and SWM (p=0.024). TMS measures revealed that both AF groups showed reduced cSP duration at 125% aMT (p>0.001) and differences in SR curves (p>0.001) than did healthy controls. Similarly, SICI (p=0.012) and LICI (p=0.009) were reduced in both AF groups compared with controls. Regression analyses revealed a significant contribution to differences in motor outcomes with the three measures of intracortical inhibition. The measures of inhibition differed, however, in terms of which performance measure they had a significant and unique predictive relationship with, reflecting the variety of participant concussion injuries. This study is the first to demonstrate differences in motor control and intracortical inhibition in AF players who had sustained concussions during their playing career two decades previously

    The geostationary tropospheric pollution explorer (GeoTROPE) mission: objectives, requirements and mission concept

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    International audienceOne of the major challenges facing atmospheric sciences is to assess, understand and quantify the impact of natural and an-thropogenic pollution on the quality of life on Earth on a local, regional and continental scale. It has become apparent that pollution originating from local/regional events can have serious effects on the composition of the lower atmosphere on a continental scale. However, to understand the effects of regional pollution on a continental scale there is a requirement to transcend traditional atmospheric spatial and temporal scales and attempt to monitor the entire atmosphere at the same time. In the troposphere the variability of chemical processes, of source strength and the dynamics induce important short term, i.e., sub-hourly, variations and significant horizontal and vertical variability of constituents and geophysical parameters relevant to a range of contemporary issues such as air quality. To study tropospheric composition, it is therefore required to link diurnal with seasonal and annual timescales, as well as local and regional with continental spatial scales, by performing sub-hourly measurements at appropriate horizontal and vertical resolution. Tropospheric observations from low-Earth orbit (LEO) platforms have already demonstrated the potential of detecting constituents relevant for air quality but they are limited, for example by the daily revisit time and local cloud cover statistics. The net result of this is that the troposphere is currently significantly under sampled. Measurements from Geostationary Orbit (GEO) offer the only practical approach to the observation of diurnal variation from space with the pertinent horizontal resolution. The Geostationary Tropospheric Pollution Explorer (GeoTROPE) is an attempt to determine tropospheric constituents with high temporal and spatial resolution. The paper will summarise the needs for geostationary observations of tropospheric composition and will give the mission objectives and the requirements
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