leishmaniasis of the lip

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Le donne e le rughe

Women take a lot of care of facial look. In this study the importance of facial wrinkles in women was asseessed. 690 Italian women were recruited and asked about the appearance of the first facial wrinkle. The 48% of women feels the first facial wrinkle as a negative sensation, for the 20% it is a maturity sign and the 32% thinks that facial wrinkles are not an important problem. The Italian women feel as negative the wrinkles around their mouth (51 %), their eyes (48%) and their neck (34%). Two third of women tries to oppose to facial wrinkles using creams or going to dermatologist or to beautician. Only the 9% of women is in favour of plastic surgery

Topical prebiotics/postbiotics and PRURISCORE validation in atopic dermatitis. International study of 396 patients

Aim: To investigate the efficacy and tolerability of a cream (Rilastil Xerolact PB) containing a mixture of prebiotics and postbiotics, and to validate the PRURISCORE itch scale in the management of atopic dermatitis. Methods: The study is based on 396 subjects of both sexes in three age groups (i.e., infants, children, adults) suffering from mild/moderate Atopic Dermatitis, recruited from 8 European countries and followed for 3 months. Results: The product demonstrated good efficacy combined with good/very good tolerability in all age groups. In particular, SCORAD, PRURISCORE and IGA scores decreased significantly over the course of the study. The PRURISCORE was preferred to VAS by the vast majority of patients. Conclusion: Even though the role of prebiotics and postbiotics was not formally demonstrated since these substances were part of a complex formulation, it can be reasonably stated that prebiotics and postbiotics have safety and standardization features that probiotics do not have. In addition they are authorized by regulatory authorities, whereas topical probiotics are not