19 research outputs found

    Numerical and experimental efficiency estimation in household battery energy storage equipment

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    Battery energy storage systems (BESS) are spreading in several applications among transmission and distribution networks. Nevertheless, it is not straightforward to estimate their performances in real life working conditions. This work is aimed at identifying test power profiles for stationary residential storage applications capable of estimating BESS performance. The proposed approach is based on a clustering procedure devoted to group daily power profiles according to their battery efficiency. By performing a k-means clustering on a large dataset of load and generation profiles, four standard charge/discharge profiles have been identified to test BESS' performances. Different clustering approaches have been considered, each of them splitting the dataset according to different properties of the profiles. A well-performing clustering approach resulted, based on the adoption of reference parameters for the clustering process of the maximum power exchanged by the BESS and the variation of battery energy content. Firstly, the results have been proven through a numerical procedure based on a BESS electrical model and on the definition of a key performance index. Then, an experimental validation has been carried out on a precommercial sodium-nickel chloride BESS: this device is available in the IoT lab of Politecnico di Milano within the H2020 InteGRIDy project

    Parathyroidectomy and survival in a cohort of Italian dialysis patients: results of a multicenter, observational, prospective study

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    Background: Severe secondary hyperparathyroidism (SHPT) is associated with mortality in end stage kidney disease (ESKD). Parathyroidectomy (PTX) becomes necessary when medical therapy fails, thus highlighting the interest to compare biochemical and clinical outcomes of patients receiving either medical treatment or surgery. Methods: We aimed to compare overall survival and biochemical control of hemodialysis patients with severe hyperparathyroidism, treated by surgery or medical therapy followed-up for 36 months. Inclusion criteria were age older than 18 years, renal failure requiring dialysis treatment (hemodialysis or peritoneal dialysis) and ability to sign the consent form. A control group of 418 patients treated in the same centers, who did not undergo parathyroidectomy was selected after matching for age, sex, and dialysis vintage. Results: From 82 Dialysis units in Italy, we prospectively collected data of 257 prevalent patients who underwent parathyroidectomy (age 58.2 ± 12.8 years; M/F: 44%/56%, dialysis vintage: 15.5 ± 8.4 years) and of 418 control patients who did not undergo parathyroidectomy (age 60.3 ± 14.4 years; M/F 44%/56%; dialysis vintage 11.2 ± 7.6 y). The survival rate was higher in the group that underwent parathyroidectomy (Kaplan–Meier log rank test = 0.002). Univariable analysis (HR 0.556, CI: 0.387–0.800, p = 0.002) and multivariable analysis (HR 0.671, CI:0.465–0.970, p = 0.034), identified parathyroidectomy as a protective factor of overall survival. The prevalence of patients at KDOQI targets for PTH was lower in patients who underwent parathyroidectomy compared to controls (PTX vs non-PTX: PTH < 150 pg/ml: 59% vs 21%, p = 0.001; PTH at target: 18% vs 37% p = 0.001; PTH > 300 pg/ml 23% vs 42% p = 0.001). The control group received more intensive medical treatment with higher prevalence of vitamin D (65% vs 41%, p = 0.0001), calcimimetics (34% vs 14%, p = 0.0001) and phosphate binders (77% vs 66%, p = 0.002). Conclusions: Our data suggest that parathyroidectomy is associated with survival rate at 36 months, independently of biochemical control. Lower exposure to high PTH levels could represent an advantage in the long term. Graphical abstract: [Figure not available: see fulltext.]

    Supporting IP Multicast Integrated Services in ATM Networks

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    This paper presents an integrated, server-based mechanism for the efficient support of the IP Integrated Services (IIS) model in ATM networks, namely the Multicast Integration Server (MIS) architecture. Instead of viewing IP-ATM multicast address resolution and QoS support separately, the approach in this paper is to consider such issues in an integrated manner. The Multicast Integration Server is capable of IP Multicast to ATM NSAP address resolution using the EAsy Multicast Routing THrough ATM clouds (EARTH) protocol, as well as of QoS management using the Resource ReSerVation Protocol (RSVP). With the use of EARTH, several ATM point-to-multipoint connections with different QoS parameters can be associated to a single IP multicast address. An RSVP server within the MIS is used to distribute RSVP messages inside the ATM cloud and to set the corresponding QoS state in the address resolution table of EARTH. In addition, this paper defines a quantized heterogeneity model which supports, ..

    Distribution Of The Human Leukocyte Antigen Class Ii Alleles In Brazilian Patients With Chronic Hepatitis C Virus Infection.

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    Hepatitis C virus (HCV) infection is a global medical problem. The current standard of treatment consists of the combination of peginterferon plus ribavirin. This regimen eradicates HCV in 55% of cases. The immune response to HCV is an important determinant of disease evolution and can be influenced by various host factors. HLA class II may play an important role in immune response against HCV. The objective of the present study was to determine the distribution of HLA class II (DRB1 and DQB1) alleles, their association with chronic HCV infection and their response to interferon therapy. One hundred and two unrelated white Brazilian patients with chronic HCV infection, 52 responders (45 males and 7 females) and 50 non-responders (43 males and 7 females) to antiviral treatment, were included in the study. Healthy Brazilian bone marrow donors of Caucasian origin from the same geographic area constituted the control group (HLA-DRB1, N = 99 and HLA-DQB1, N = 222 individuals). HLA class II genotyping was performed using a low-resolution DRB1, DQB1 sequence-specific primer amplification. There were higher frequencies of HLA-DRB1*13 (26.5 vs 14.1%) and HLA-DQB1*02 (52.9 vs 38.7%) in patients compared with controls; however, these were not significantly different after P correction (Pc = 0.39 and Pc = 0.082, respectively). There was no significant difference between the phenotypic frequencies of HLA-DRB1 (17.3 vs 14.0%) and HLA-DQB1 alleles in responder and non-responder HCV patients. The HLA-DRB1*07 allele was significantly more common in HCV patients (33.3 vs 12.1%) than in controls (Pc = 0.0039), suggesting that the HLA-DRB1*07 allele is associated with chronic HCV infection.41884-
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