SVOM pointing strategy: how to optimize the redshift measurements?

The Sino-French SVOM mission (Space-based multi-band astronomical Variable Objects Monitor) has been designed to detect all known types of gamma-ray bursts (GRBs) and to provide fast and reliable GRB positions. In this study we present the SVOM pointing strategy which should ensure the largest number of localized bursts allowing a redshift measurement. The redshift measurement can only be performed by large telescopes located on Earth. The best scientific return will be achieved if we are able to combine constraints from both space segment (platform and payload) and ground telescopes (visibility).Comment: Proceedings of Gamma-Ray Bursts 2007 conference, Santa Fe, USA, 5-9 November 2007. Published in AIP conf. proc. 1000, 585-588 (2008

Representation theory of some infinite-dimensional algebras arising in continuously controlled algebra and topology

In this paper we determine the representation type of some algebras of infinite matrices continuously controlled at infinity by a compact metrizable space. We explicitly classify their finitely presented modules in the finite and tame cases. The algebra of row-column-finite (or locally finite) matrices over an arbitrary field is one of the algebras considered in this paper, its representation type is shown to be finite.Comment: 33 page

Anisotropic Dirac fermions in a Bi square net of SrMnBi2

We report the highly anisotropic Dirac fermions in a Bi square net of SrMnBi2, based on a first principle calculation, angle resolved photoemission spectroscopy, and quantum oscillations for high-quality single crystals. We found that the Dirac dispersion is generally induced in the (SrBi)+ layer containing a double-sized Bi square net. In contrast to the commonly observed isotropic Dirac cone, the Dirac cone in SrMnBi2 is highly anisotropic with a large momentum-dependent disparity of Fermi velocities of ~ 8. These findings demonstrate that a Bi square net, a common building block of various layered pnictides, provide a new platform that hosts highly anisotropic Dirac fermions.Comment: 5 pages, 4 figure

Phase appearance or disappearance in two-phase flows

This paper is devoted to the treatment of specific numerical problems which appear when phase appearance or disappearance occurs in models of two-phase flows. Such models have crucial importance in many industrial areas such as nuclear power plant safety studies. In this paper, two outstanding problems are identified: first, the loss of hyperbolicity of the system when a phase appears or disappears and second, the lack of positivity of standard shock capturing schemes such as the Roe scheme. After an asymptotic study of the model, this paper proposes accurate and robust numerical methods adapted to the simulation of phase appearance or disappearance. Polynomial solvers are developed to avoid the use of eigenvectors which are needed in usual shock capturing schemes, and a method based on an adaptive numerical diffusion is designed to treat the positivity problems. An alternate method, based on the use of the hyperbolic tangent function instead of a polynomial, is also considered. Numerical results are presented which demonstrate the efficiency of the proposed solutions

Further studies of 1E 1740.7-2942 with ASCA

We report the ASCA results of the Great Annihilator 1E 1740.7-2942 obtained with five pointing observations in a time span of 3.5 years. The X-ray spectrum for each period is well fitted with a single power-law absorbed by a high column of gas. The X-ray flux changes by a factor of 2 from period to period, but the other spectral parameters show no significant change. The photon index is flat with \Gamma = 0.9--1.3. The column densities of hydrogen N_H is $\sim$ 1.0 x 10^{23} H cm^{-2} and that of iron N_{Fe} is $\sim$ 10^{19} Fe cm^{-2}. These large column densities indicate that 1E 1740.7-2942 is near at the Galactic Center. The column density ratio leads the iron abundance to be 2 times larger than the other elements in a unit of the solar ratio. The equivalent width of the K\alpha-line from a neutral iron is less than 15 eV in 90% confidence. This indicates that the iron column density within several parsecs from 1E 1740.7-2942 is less than 5 x 10^{17} Fe cm^{-2}. In addition, the derived hydrogen column density is about 1/6 of that of giant molecular clouds in the line of sight. All these facts support that 1E 1740.7-2942 is not in a molecular cloud, but possibly in front of it; the X-rays are not powered by accretion from a molecular cloud, but from a companion star like ordinary X-ray binaries.Comment: To appear in ApJ July 20, 1999 issue, Vol. 520 #1, 23 pages LaTeX files, uses aasms4.sty and psfig.sty, also available at http://www-cr.scphys.kyoto-u.ac.jp/member/sakano/work/paper/index-e.htm

Nuclear magnetic resonance as a quantitative tool to study interactions in biomacromolecules

High-resolution nuclear magnetic resonance (NMR) has emerged as one of the most versatile tools for the quantitative study of structure, kinetics, and thermodynamics of biomolecules and their interactions at atomic resolution. Traditionally, nuclear Overhauser enhancements (NOEs) and chemical shift perturbation methods are used to determine molecular geometries and to identify contact surfaces, but more recently, weak anisotropic orientation, anisotropic diffusion, and scalar couplings across hydrogen bonds provide additional information. Examples of such technologies are shown as applied to the quantitative characterization of function and thermodynamics of several biomacromolecules. In particular, (1) the structural and dynamical changes of the TipA multidrug resistance protein are followed upon antibiotic binding, (2) the trimer-monomer equilibrium and thermal unfolding of foldon, a small and very efficient trimerization domain of the T4 phagehead, is described in atomic detail, and (3) the changes of individual protein hydrogen bonds during thermal unfolding are quantitatively followed by scalar couplings across hydrogen bond

Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial

Purpose: Functionally critically located gliomas represent a challenging subgroup of intrinsic brain neoplasms. Standard therapeutic recommendations often cannot be applied, because radical treatment and preservation of neurological function are contrary goals. The successful targeting of gliomas with locally injected beta radiation-emitting 90Y-DOTAGA-substance P has been shown previously. However, in critically located tumours, the mean tissue range of 5mm of 90Y may seriously damage adjacent brain areas. In contrast, the alpha radiation-emitting radionuclide 213Bi with a mean tissue range of 81µm may have a more favourable toxicity profile. Therefore, we evaluated locally injected 213Bi-DOTA-substance P in patients with critically located gliomas as the primary therapeutic modality. Methods: In a pilot study, we included five patients with critically located gliomas (WHO grades II-IV). After diagnosis by biopsy, 213Bi-DOTA-substance P was locally injected, followed by serial SPECT/CT and MR imaging and blood sampling. Besides feasibility and toxicity, the functional outcome was evaluated. Results: Targeted radiopeptide therapy using 213Bi-DOTA-substance P was feasible and tolerated without additional neurological deficit. No local or systemic toxicity was observed. 213Bi-DOTA-substance P showed high retention at the target site. MR imaging was suggestive of radiation-induced necrosis and demarcation of the tumours, which was validated by subsequent resection. Conclusion: This study provides proof of concept that targeted local radiotherapy using 213Bi-DOTA-substance P is feasible and may represent an innovative and effective treatment for critically located gliomas. Primarily non-operable gliomas may become resectable with this treatment, thereby possibly improving the prognosi