A persistent and dynamic East Greenland Ice Sheet over the past 7.5 million years

Climate models show that ice-sheet melt will dominate sea-level rise over the coming centuries, but our understanding of ice-sheet variations before the last interglacial 125,000 years ago remains fragmentary. This is because terrestrial deposits of ancient glacial and interglacial periods1,2,3 are overrun and eroded by more recent glacial advances, and are therefore usually rare, isolated and poorly dated4. In contrast, material shed almost continuously from continents is preserved as marine sediment that can be analysed to infer the time-varying state of major ice sheets. Here we show that the East Greenland Ice Sheet existed over the past 7.5 million years, as indicated by beryllium and aluminium isotopes (10Be and 26Al) in quartz sand removed by deep, ongoing glacial erosion on land and deposited offshore in the marine sedimentary record5,6. During the early Pleistocene epoch, ice cover in East Greenland was dynamic; in contrast, East Greenland was mostly ice-covered during the mid-to-late Pleistocene. The isotope record we present is consistent with distinct signatures of changes in ice sheet behaviour coincident with major climate transitions. Although our data are continuous, they are from low-deposition-rate sites and sourced only from East Greenland. Consequently, the signal of extensive deglaciation during short, intense interglacials could be missed or blurred, and we cannot distinguish between a remnant ice sheet in the East Greenland highlands and a diminished continent-wide ice sheet. A clearer constraint on the behaviour of the ice sheet during past and, ultimately, future interglacial warmth could be produced by 10Be and 26Al records from a coring site with a higher deposition rate. Nonetheless, our analysis challenges the possibility of complete and extended deglaciation over the past several million years

Recent transformation of intertidal environments under a sea-level rise scenario: Examples from northern Spain

The transformation of two intertidal environments from northern Spain during the last 150 years shows an evolution from a tidal flat into a salt marsh environment, with an intermediate transitional stage. The environment of deposition was reconstructed based on benthic foraminifera and sand content. Sediments were put into a temporal framework using short-lived radioisotope activities and heavy metal concentrations. The observed natural evolution responds to the availability of abundant sediment and the current sea-level rise scenario, where intertidal environments are trying to adapt to increasing flooding periods by accreting sediment rapidly. © 2019 Sociedad Geologica de Espana. All rights reserved.This research was funded by the Mi nistry of Economy and Competitiveness of Spain (CGL2013-41083-P), the University of the Basque Country UPV/EHU (UFI11/09), and the Basque Government (IT976-16). Ane García-Artola was funded by the Basque Government (BFI08.180). Miriam Torrontegui Aguado carried out the micropalaeontological analysis of the PR core and Eduardo Leorri (East Carolina University, USA) helped in the field. We thank Juan Usera (Universitat de Valèn-cia), an anonymous reviewer, and Manuel Díaz Azpiroz (Assistant Editor) for their valuable comments. This work represents contribution #29 of the Geo-Q Zentroa Research Unit (Joaquín Gómez de Llarena Laboratory)

Proton Cyclotron Features in Thermal Spectra of Ultra-magnetized Neutron Stars

A great deal of interest has been recently raised in connection with the possibility that soft $\gamma$-ray repeaters (SGRs) and anomalous X-ray pulsars (AXPs) contain {\em magnetars}, young neutron stars endowed with magnetic fields $\gtrsim 10^{14}$ G. In this paper we calculate thermal spectra from ultra-magnetized neutron stars for values of the luminosity and magnetic field believed to be relevant to SGRs and AXPs. Emergent spectra are found to be very close to a blackbody at the star effective temperature and exhibit a distinctive absorption feature at the proton cyclotron energy $E_{c,p}\simeq 0.63 (B/10^{14} {\rm G})$ keV. The proton cyclotron features (PCFs) are conspicuous (equivalent width of up to many hundreds eV) and relatively broad ($\Delta E/E \sim 0.05-0.2$). The detection of the PCFs is well within the capabilities of present X-ray spectrometers, like the HETGS and METGS on board Chandra. Their observation might provide decisive evidence in favor of the existence of magnetars.Comment: 7 pages, 4 figures, minor changes included, typos corrected. Accepted for publication in Ap

A Viewing Angle - Kinetic Luminosity Unification Scheme For BL Lacertae Objects

We propose a unified classification for BL Lac objects (BLs), focusing on the synchrotron peak frequency of the spectral energy distribution. The unification scheme is based on the angle Theta that describes the orientation of the relativistic jet and on the electron kinetic luminosity Lambda of the jet. We assume that Lambda scales with the size of the jet r in a self-similar fashion (Lambda propto r^2), as supported by observational data. The jets are self-similar in geometry and have the same pressure and median magnetic field at the inlet, independent of size. The self-similarity is broken for the highest energy electrons, which radiate mainly at high frequencies, since for large sources they suffer more severe radiative energy losses over a given fraction of the jet length. We calculate the optically thin synchrotron spectrum using an accelerating inner jet model based on simple relativistic gas dynamics and show that it can fit the observed infrared to X-ray spectrum of PKS 2155--304. We couple the accelerating jet model to the unification scheme and compare the results to complete samples of BLs. The negative apparent evolution of X-ray selected BLs is explained as a result of positive evolution of the jet electron kinetic luminosity $\Lambda_{kin}$. We review observational arguments in favor of the existence of scaled-down accretion disks and broad emission-line regions in BLs. The proposed unification scheme can explain the lack of observed broad emission lines in X-ray selected BLs, as well as the existence of those lines preferentially in luminous radio-selected BLs. Finally, we review observational arguments that suggest the extension of this unification scheme to all blazars.Comment: 32 pages, 8 figures, to be published in the ApJ (Oct 20, 1998

Draft Genome Sequence of the Iron-Oxidizing, Acidophilic, and Halotolerant “Thiobacillus prosperus” Type Strain DSM 5130

“Thiobacillus prosperus” is a halotolerant mesophilic acidophile that gains energy through iron and sulfur oxidation. Its physiology is poorly understood. Here, we describe the principal genomic features of the type strain of T. prosperus, DSM 5130. This is the first public genome sequence of an acidophilic halotolerant bacterium

The Accretion Rates and Spectral Energy Distributions of BL Lacertae Objects

We investigate the relationship between accretion rates and the spectral energy distributions (SEDs) of BL Lac objects, using a sample of objects for which published information on the host galaxies, emission-line luminosities, and peak frequencies and luminosities of their SEDs are available. The sample is composed of 43 BL Lac objects which have a relatively continuous distribution of peak frequencies. Under the assumption that the observed emission lines are photoionized by the central accretion disk, we use the line luminosities to estimate the accretion luminosities and hence accretion rates. We find that low frequency-peaked BL Lac objects (LBLs) span a wide range of accretion rates, whereas high frequency-peaked BL Lac objects (HBLs) cover a more restricted range of lower values. There appears to be a continuous distribution of accretion rates between the two subclasses of BL Lac objects. We find that the peak frequency of the SED, \pknu, correlates with the accretion rate, approximately with the form \pknu\propto \Lambda^{-3} in HBLs and \pknu \propto \Lambda^{-0.25} in LBLs, where $\Lambda \equiv L_{\rm lines}/c^2$. The peak luminosity of the SED is also correlated with $\Lambda$. These results suggest that the accretion rate influences the shape of the SED in BL Lac objects. They also support models which couple the jet and the accretion disk. We present a physical scenario to account for the empirical trends.Comment: 6 pages in emulateapj.sty, 3 figures 1 table. The Astrophysical Journal (in press

ASCA and contemporaneous ground-based observations of the BL Lacertae objects 1749+096 and 2200+420 (BL Lac)

We present ASCA observations of the radio-selected BL Lacertae objects 1749+096 (z=0.32) and 2200+420 (BL Lac, z=0.069) performed in 1995 Sept and Nov, respectively. The ASCA spectra of both sources can be described as a first approximation by a power law with photon index Gamma ~ 2. This is flatter than for most X-ray-selected BL Lacs observed with ASCA, in agreement with the predictions of current blazar unification models. While 1749+096 exhibits tentative evidence for spectral flattening at low energies, a concave continuum is detected for 2200+420: the steep low-energy component is consistent the high-energy tail of the synchrotron emission responsible for the longer wavelengths, while the harder tail at higher energies is the onset of the Compton component. The spectral energy distributions from radio to gamma-rays are consistent with synchrotron-self Compton emission from a single homogeneous region shortward of the IR/optical wavelengths, with a second component in the radio domain related to a more extended emission region. For 2200+420, comparing the 1995 Nov state with the optical/GeV flare of 1997 July, we find that models requiring inverse Compton scattering of external photons provide a viable mechanism for the production of the highest (GeV) energies during the flare. An increase of the external radiation density and of the power injected in the jet can reproduce the flat gamma-ray continuum observed in 1997 July. A directly testable prediction of this model is that the line luminosity in 2200+420 should vary shortly after (~1 month) a non-thermal synchrotron flare.Comment: 28 pages,6 figures, 5 tables; LaTeX document. accepted for publication in the Astrophysical Journa

Effects of combined drug treatments on Plasmodium falciparum : in vitro assays with doxycycline, ivermectin and efflux pump inhibitors

There is great concern regarding the rapid emergence and spread of drug-resistance in Plasmodium falciparum, the parasite responsible for the most severe form of human malaria. Parasite populations resistant to some or all the currently available antimalarial treatments are present in different world regions. Considering the need for novel and integrated approaches to control malaria, combinations of drugs were tested on P. falciparum. The primary focus was on doxycycline, an antibiotic that specifically targets the apicoplast of the parasite. In combination with doxycycline, three different drugs known to inhibit efflux pumps (verapamil, elacridar and ivermectin) were tested, with the assumption that they could increase the intracellular concentration of the antibiotic and consequently its efficacy against P. falciparum. We emphasize that elacridar is a third-generation ABC transporters inhibitor, never tested before on malaria parasites. In vitro experiments were performed on asexual stages of two strains of P. falciparum, chloroquine-sensitive (D10) and chloroquineresistant (W2). Incubation times on asynchronous or synchronous cultures were 72h or 96h, respectively. The antiplasmodial effect (i.e. the IC50) was determined by measuring the activity of the parasite lactate dehydrogenase, while the interaction between drugs was determined through combination index (CI) analyses. Elacridar achieved an IC50 concentration comparable to that of ivermectin, approx. 10-fold lower than that of verapamil, the other tested ABC transporter inhibitor. CI results showed synergistic effect of verapamil plus doxycycline, which is coherent with the starting hypothesis, i.e. that ABC transporters represent potential targets, worth of further investigations, towards the development of companion molecules useful to enhance the efficacy of antimalarial drugs. At the same time, the observed antagonistic effect of doxycycline in combination with ivermectin or elacridar highlighted the importance of drug testing, to avoid the de-facto generation of a sub-dosage, a condition that facilitates the development of drug resistance

Moving from a Product-Based Economy to a Service-Based Economy for a More Sustainable Future

Traditionally, economic growth and prosperity have been linked with the availability, production and distribution of tangible goods as well as the ability of consumers to acquire such goods. Early evidence regarding this connection dates back to Adam Smith's Wealth of Nations (1776), in which any activity not resulting in the production of a tangible good is characterized as unproductive of any value." Since then, this coupling of economic value and material production has been prevalent in both developed and developing economies throughout the world. One unintended consequence of this coupling has been the exponential increase in the amount of solid waste being generated. The reason is that any production and consumption of material goods eventually generates the equivalent amount of (or even more) waste. Exacerbating this problem is the fact that, with today's manufacturing and supply chain management technologies, it has become cheaper to dispose and replace most products rather than to repair and reuse them. This has given rise to what some call a disposable society." To put things in perspective: In 2012 households in the U.K. generated approximately 22 thousand tons of waste, which amounted to 411 kg of waste generated per person (Department for Environment, Food & Rural Affairs, 2015). During the same time period, households in the U.S. generated 251 million tons of waste, which is equivalent to a person generating approximately 2 kg of waste every day (U.S. Environmental Protection Agency, 2012). Out of these 251 million tons of total waste generated, approximately 20% of the discarded items were categorized as durable goods. The disposal of durable goods is particularly worrisome because they are typically produced using material from non- renewable resources such as iron, minerals, and petroleum-based raw materials