The Motivation To Volunteer: Understanding Volunteer Motivation at United States Industrial Heritage Museums and Organizations

Industrial Heritage Museums and Organizations (IHMOs) in the United States (US) and their volunteers are underrepresented in the literature on volunteerism. The motivation and demographics of volunteers in IHMOs within the US are examined in this paper. Research into this topic is exploratory and little is known, therefore any hypothesis was based on personal observations as an AmeriCorps VISTA member in a variety of US museums. An online survey was sent out to three hundred and eighty-five museums across the US, along with conducting twelve in-person or over-the-phone interviews with museum practitioners and volunteers. This research found that a majority of IHMO volunteers are sixty years or older, male, white, hold a bachelor’s degree, and/or are retired. The results of this research indicate a lack of age, gender, and race/ethnic inclusivity within IHMOs. I provide discussion on how IHMOs may be able to increase volunteer activity through the inclusivity of minority and disserviced groups, as well as how topics, such as industrial heritage, industrialization and de-industrialization, and familial ties play into volunteer motivation

The Role of Cold Acclimatization on the Biogeography of the Mountain Chickadee (Parus gambeli) and the Juniper Titmouse (Parus ridgwayi)

Biogeographic patterns of animals are shaped by biotic interactions, such as competition, and by abiotic factors, such as climate. Mountain Chickadees (Parus gambeli) and Juniper Titmice (Parus ridgway) are permanent residents of regions of western North America and are ecologically similar, but have different northern range limits. l measured several physiological variables, including basal metabolic rate (BMR), peak metabolic rate (PMR = maximal thermogenic capacity), metabolic response to varying environmental temperature (MRT), evaporative water loss (EWL), and daily energy expenditure (DEE) for summer-and winter-acclimatized Mountain Chickadees and Juniper Titmice to determine if seasonal and interspecific variation in cold tolerance and thermogenic ability shape the northern range distribution of these two species. In addition, I examined the ecological consequences of nocturnal hypothermia and cavity roosting in seasonally acclimatized Mountain Chickadees and Juniper Titmice. Winter birds tolerated colder test temperatures than summer birds for both species This improved cold tolerance was associated with a significant increase in PMR in winter chickadees (27.1 %) and titmice (114%) compared to summer. BMR was significantly higher in winter birds (16.0%) compared to summer birds for both species. BMR and PMR were significantly higher for chickadees compared to titmice in both summer and winter. Winter chickadees were able to withstand colder test temperatures than winter titmice. The Mountain Chickadee\u27s lower critical temperature is lower than the Juniper Titmouse\u27s in summer and in winter. The Mountain Chickadee\u27s upper critical temperature is also lower than the Juniper Titmouse\u27s and chickadees also had significantly higher evaporative water loss rates compared to titmice. Seasonal acclimatization in Mountain Chickadees involves insulatory as well as metabolic changes. For Juniper Titmice winter acclimatization appears to be primarily a metabolic process. The laboratory metabolism data for activity costs associated with DEE revealed that foraging energy requirements were not significantly higher than alert perching energy requirements. DEE was significantly higher (P\u3c0.05) in winter-acclimatized chickadees and titmice compared to their summer counterparts. The marked increase in calculated DEE in winter birds compared to summer contrasts a pattern of increased DEE in the breeding season for several avian species. The data from this study indicate that the northern range limit of small birds can be limited by energetic and water balance demands

Patient-reported outcomes in inflammatory bowel disease:a measurement of effect in research and clinical care

The measurement of outcomes is key in evaluating healthcare or research interventions in inflammatory bowel disease (IBD). In patient-centred care, patient-reported outcome measures (PROMs) are central to this evaluation. In this review, we provide an overview of validated, adult disease-specific PROMs developed for use in IBD. Our aim is to assist clinicians and researchers in selection of PROMs to measure outcomes in their patient cohort. The Consensus-based Standards for the Selection of Health Measurement Instruments database of systematic reviews was the primary resource used to identify PROMs used in IBD. Search terms were ‘Crohn’s disease’, ‘ulcerative colitis’, and ‘IBD’. Seven systematic reviews were identified from this search. In addition, the publication by the IBD Core Outcome Set Working Group was used to identify further PROMs. Three systematic reviews were excluded as they did not meet the inclusion criteria. From the five included systematic reviews, we identified 21 PROMs and their shortened versions. In conclusion, it does not appear that any one PROM is entirely suitable for both research and clinical practice. Overall, the IBDQ-32 is most widely used in research but has the limitation of cost, whereas the IBD-Control has been recommended in the clinical core outcome set

Detection of IgG4-Specific Autoantibodies in Rheumatoid Arthritis Serum Samples

Background: Rheumatoid arthritis (RA) is a chronic multi-system autoimmune disease characterized by inflammatory synovitis. Autoantibodies such as rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) have been implicated in the pathogenesis of RA, and are currently important criteria for diagnosis within the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria.1 Yet, many patients diagnosed with RA do not have measurable circulating ACPA or RF which may result in delayed diagnosis and treatment. After IgG1, IgG4 is the second most predominant isotype among ACPA and RF; however it is not detected in currently available diagnostic assays. Recent data have demonstrated that patients deemed “sero-negative” based on standard assays may have high titers of IgG4-specific ACPA and/or RF. Objectives: The purpose of this study is to quantitate and compare IgG1- to IgG4-specific anti-CCP antibodies and rheumatoid factor in patients with rheumatoid arthritis. We will determine the frequency of IgG4 autoantibodies, and examine whether they have a differential expression among RA patients. We will also correlate their presence with disease activity, anti-rheumatic drug therapy, and levels of serum cytokines. Ultimately, this work may help to determine if a diagnostic test that detects IgG4 isotype of ACPA and RF will aid in earlier diagnosis and better characterization of rheumatoid arthritis. Methods: To explore our objectives, we have initiated a cross-sectional study with the goal of enrolling 1,000 patients with a confirmed diagnosis of rheumatoid arthritis, based on the 2010 ACR/EULAR classification criteria.1 We are collecting clinical information about each patient including demographics, current treatments, clinical disease activity, laboratory values, and radiographic results. Concurrently, we are collecting serum samples from each patient that will be analyzed for 1) total levels of IgG4 and IgG1; 2) total ACPA and RF; 3) levels of IgG1-specific and IgG4-specific ACPA and RF; and 4) cytokine levels (IL-6, TNF, IL-1, IL-17, IFNy, IL-21, and G-CSF). Results: To date, we have recruited 102 RA patients including 70 females (68.6%) and 32 males (31.4%). Their ages range from 24 to 85 years (mean 58.4 ± 12.4 years). Acute phase reactant levels were available for 98 of the 102 patients, allowing calculation of the disease activity score using 28 joints (DAS28). The mean DAS28 was 3.67 ± 1.0, which is within the moderate disease activity range. The proportion of patients in each disease category was: remission (12.2%), low disease activity (21.4%), moderate disease activity (61.2%), and high disease activity (6.1%). Based on their medical records, at any point in time, 46.1% (n=47) of the recruited subjects had positive RF titers vs. 39.2% (n=40) without RF; 58.8% (n=60) had ACPA vs 26.5% (n=27) without ACPA. For 14.7% (n=15) of the subjects, RF and/or ACPA were either unknown or untested. Of patients with RF, 91.4% (n=43) also had ACPA; of patients with ACPA, 71.7% % (n=43) also had RF. Of the patients tested for both, 27.9% (n=24) were negative for both RF and ACPA. Conclusion: Subject recruitment and data collection are well underway for this large cross-sectional study that will shed light to the role of IgG4- specific autoantibodies in the pathogenesis and diagnosis of rheumatoid arthritis. Reference: 1Aletaha D Neogi T, Silman A, et al. 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 2010; 62(9):2569-81/Ann Rheum Dis. 2010; 69:1580-8

"The dirty hand in the latex glove": a study of hand hygiene compliance when gloves are worn.

Wearing of gloves reduces transmission of organisms by healthcare workers' hands but is not a substitute for hand hygiene. Results of previous studies have varied as to whether hand hygiene is worse when gloves are worn. Most studies have been small and used nonstandardized assessments of glove use and hand hygiene. We sought to observe whether gloves were worn when appropriate and whether hand hygiene compliance differed when gloves were worn

Federal Judicial Selection

“The First Two Centuries”: The first panel explored the provisions that the drafters made in the United States Constitution for federal judicial selection and traced the two-century history of the selection process following the constitution\u27s adoption. The panel consisted of Charles Cooper, Esq. of Cooper & Kirk PLLC; Gary L. McDowell, Haynes Professor of Leadership Studies and Political Science at the University of Richmond’s Jepson School of Leadership Studies; and Ms. Maeva Marcus, of the United States Supreme Court Historical Society. Rodney A. Smolla, the George E. Allen Chair in Law, served as program coordinator and moderator. “Modern Federal Judicial Selection”: The second panel explored modern federal judicial selection, tracing the selection process over the last two decades and analyzing how it has grown increasingly contentious. The panel consisted of Theresa M. Beiner, of the William H. Bowen School of Law at the University of Arkansas at Little Rock; Sheldon Goldman, Department of Political Science University of Massachusetts; Judge Edith Jones, U.S. Court of Appeals for the Fifth Circuit; and William P. Marshall, the Kenan Professor of Law University of North Carolina School of Law. Carl W. Tobias, Williams Professor of Law at the University of Richmond School of Law, served as moderator. “The Prospects of Reform”: The third panel explored numerous suggestions for remedying or ameliorating the difficulties that pervade modern federal judicial selection and the prospects for these measures\u27 success. The panel consisted of Terry Eastland, Publisher of The Weekly Standard; Michael Gerhardt, Hanson Professor of Law at the Marshall-Wythe School of Law, College of William and Mary; and Sanford V. Levinson, The W. St. John Garwood Centennial Chair in Law and Professor of Government at the University of Texas School of Law. Gary L. McDowell, the Haynes Professor of Leadership Studies and Political Science at the University of Richmond’s Jepson School of Leadership Studies, served as moderator