Faculty Recital: Geoffrey Duce and Jameson Cooper

Kemp Recital HallApril 11, 2016Monday Evening8:00 p.m

Processed meat consumption and Lung function: modification by antioxidants and smoking

This article has supplementary material available from www.erj.ersjournals.com: This study was supported by the Medical Research Council, UK. H. Okubo was supported in part by fellowship of the Astellas Foundation for Research on Metabolic Disorders, Japan and the Naito Memorial Grant for Research Abroad from the Naito Foundation, Japan

P324 RADIOGRAPHIC KNEE OSTEOARTHRITIS IS ASSOCIATED WITH AN INCREASE IN TRABECULAR BUT NOT CORTICAL BONE MINERAL DENSITY USING PERIPHERAL QUANTITATIVE CT

Digitalitzat per Artypla

The developmental origins of sarcopenia: using peripheral quantitative computed tomography to assess muscle size in older people

Background: a number of studies have shown strong graded positive relationships between size at birth, grip strength, and estimates of muscle mass in older people. However no studies to date have included direct measures of muscle size. Methods: we studied 313 men and 318 women born in Hertfordshire, United Kingdom between 1931 and 1939 who were still resident there and had historical records of growth in early life. Information on lifestyle was collected. and participants underwent peripheral quantitative computed tomography to directly measure forearm and calf muscle size. Results: birth weight was positively related to forearm muscle area in the men (r = 0.24. p &lt; .0001) and women (r = 0.17, p = .003). There were similar but weaker associations between birth weight and calf muscle area in the men (r = 0.13, p = .03) and in the women (r = 0.17, p = .004). These relationships were all attenuated by adjustment for adult size. Conclusion: we present first evidence that directly measured muscle size in older men and women is associated with size at birth. This may reflect tracking of muscle size and is important because it suggests that benefit may be gained from taking a life course approach both to understanding the etiology of sarcopenia and to developing effective interventions<br/

Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study

We looked for interaction between early environment and adult lifestyle in determination of bone mineral content (BMC) and bone mineral density (BMD) among 498 men and 468 women for whom birth records were available. Participants completed a health questionnaire, and bone densitometry (DXA) of the lumbar spine and femoral neck performed

Relationships between bone geometry, volumetric bone mineral density and bone microarchitecture of the distal radius and tibia with alcohol consumption

PurposeChronic heavy alcohol consumption is associated with bone density loss and increased fracture risk, while low levels of alcohol consumption have been reported as beneficial in some studies. However, studies relating alcohol consumption to bone geometry, volumetric bone mineral density (vBMD) and bone microarchitecture, as assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT), are lacking.MethodsHere we report an analysis from the Hertfordshire Cohort Study, in which we studied associations between HR-pQCT measures at the distal radius and tibia and alcohol consumption in 376 participants (198 men and 178 women) aged 72.1–81.4 years.ResultsA total of 30 (15.2%), 90 (45.5%) and 78 (39.4%) men drank minimal/none (&lt; 1 unit/week), low (? 1 unit/week and &lt; 11 units/week) and moderate/high (? 11 units/week) amounts of alcohol respectively. These figures were 74 (41.8%), 80 (45.2%) and 23 (13.0%) respectively in women for minimal/none (&lt; 1 unit/week), low (? 1 unit/week and &lt; 8 units/week) and moderate/high (? 8 units/week). At the distal radius, after adjustment for confounding factors (age, BMI, smoking status, dietary calcium intake, physical activity and socioeconomic status and years since menopause and HRT use for women), men that drank low alcohol had lower cortical thickness (p = 0.038), cortical vBMD (p = 0.033), and trabecular vBMD (p = 0.028) and higher trabecular separation (p = 0.043) than those that drank none/minimal alcohol. Similar differences were shown between minimal/none and moderate/high alcohol although these only reached statistical significance for the cortical parameters. Interestingly, after similar adjustment, women showed similar differences in the trabecular compartment between none/minimal alcohol and low alcohol at the distal tibia. However, women that drank moderate/high alcohol had significantly higher trabecular vBMD (p = 0.007), trabecular thickness (p = 0.026), and trabecular number (p = 0.042) and higher trabecular separation (p = 0.026) at the distal radius than those that drank low alcohol.ConclusionsOur results suggest that alcohol consumption (low and moderate/high) may have a detrimental impact on bone health in men in both the cortical and trabecular compartments at the distal radius with similar results in women in the trabecular compartment between none/minimal alcohol and low alcohol at the distal tibia suggesting that avoidance of alcohol may be beneficial for bone health.AbbreviationsaBMD, areal bone mineral density; BMI, body mass index; Ct. area, cortical area; Ct.vBMD, cortical density; Ct.Po, cortical porosity; Ct.Th, cortical thickness; DXA, dual energy X-ray absorptiometry; HCS, Hertfordshire Cohort Study; HRpQCT, high-resolution peripheral quantitative computed tomography; pQCT, peripheral quantitative computed tomography; Tt.area, total cross-sectional area; Tb.vBMD, trabecular BMD; Tb.N, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; vBMD, volumetric bone mineral density

The Grizzly, February 19, 2009

Opening Minds and Hearts • Alumni Advice • Lecturer Dr. Andrew Delbanco Reviews Lincoln Now and Then • Thai Spice is Giving You a Taste of a Different Part of Asia • Sexually Transmitted Diseases: Cautionary Reminder • Fresh Talent, New Face: Heather Dougherty Visits Ursinus • French TA Spotlight: Vincent Brousse • Opinions: Reading for Pleasure? Trilogies Will Have You Hooked; There is Always Time to Learn: Confessions of an Art Enthusiasthttps://digitalcommons.ursinus.edu/grizzlynews/1780/thumbnail.jp

The Grizzly, September 25, 2008

Another Fantastically Fun-Filled Family Day for Ursinus College • Worcester High School Pregnancy Pact Fact? • So Long Shea Stadium • Lower Draws Crowds • Ursinus Students to Attend Activist Workshop at Swarthmore • UC Writing Center? What\u27s That? • UC Fringe Cabaret Strikes a Chord with Music, Improv and Acrobatics • Abroad in Germany: Culture Shock! • Up \u27Til Dawn Awareness Week at UChttps://digitalcommons.ursinus.edu/grizzlynews/1769/thumbnail.jp