Epistemology, Structure and Urgency: the Sociology of Financial and Scientific Journalists

This paper, which examines the work of journalists in one field, argues for the value of including journalists\' own understandings and practices in analyses of the role of the media. Moreover it suggests that, in this field, there may be more commonalities between the practices of journalism and social science than is commonly supposed. The paper is based upon a set of interviews with scientific and financial journalists, covering their interpretations of nanotechnologies and their development. Whereas much of the social scientific work to date in this area has been concerned with the public understanding of science, and the role that journalism plays in relation to this, our study addresses the parallel issue of how, in a field characterised by high levels of commercialisation, potential investors get information and make judgments about particular applications, and the extent to which journalism plays a key role in this process. Here, we focus not primarily on the ways in which the media frame understandings of a complex technology, important though they may be, but on the practical epistemological strategies that journalists employ to make sense of it. We argue that journalists can be seen to be engaged in epistemological strategies that are analogous to those of sociologists, and that this dimension is too easily missed by approaches that, for example, recommend that the correct unit of analysis should always be journalism rather than journalists. We conclude by suggesting that, whilst the general applicability of our argument to other fields of journalism is necessarily an empirical question, our approach may have more general significance for debates about the critical role of social science.Epistemology, Fields, Financial Understanding of Science, Nanotechnology, Sociology of Journalists, Scepticism, STS

Local taxation, spending and poverty : new choices and tax justice

In the environment of the 2014 Independence Referendum, a number of key questions have been raised about the future Scotland we want to see and live in. Core to such discussions have been the interventions on wealth creation and benefits, by the leaders of the Conservatives and Labour Parties in Scotland, respectively. However, and as rigorously debated in the Whose Economy? Seminar Series (Danson and Trebeck, 2011), such questions need to be considered in their wider contexts to identify and analyse fully all aspects of ‘who pays?’ and ‘who benefits?’. Indeed, several of the papers to that seminar series echoed previous classical work on poverty and the welfare state by Townsend, Abel-Smith and others which confirmed there are some long-standing myths to be addressed. These commentaries have suggested that all is not what it seems in the review of statistics of income and benefits, and robust, objective and clinical assessment of the dat

Representing the user: a sociological study of the discourse of human computer interaction

The discipline of Human Computer Interaction (HCI) was established in the early 1980's on the foundations of cognitive psychology, computer science and ergonomics. In recent years however, claims have been made for the relevance of forms of sociology to this avowedly multidisciplinary field, and a number of sociologists have attempted to contribute to the general enterprise of developing a deeper understanding of the computer user and thereby informing, and improving, software design. This thesis is, in one sense, a continuation of this emerging body of work. However, my contention is that little, if any, critical attention has been given within this work to questions that would seem to be of fundamental importance to attempts at collaboration between disciplines: how is the disciplinary organization of knowledge to be understood, and more specifically, can HCI be adequately described in the simple pluralist terms in which it tends to characterise itself? The primary focus then is on the discipline of HCI. Utilising a theoretical model which considers disciplines as distinctive discourses which constitute their own domains of objects, I analyse the discourse and practice of HCI in order to explicate some of its underlying premises and assumptions, and to argue that it has, unavoidably, set many of the parameters within which contributing disciplines must operate. Texts, audio and video tapes, and ethnographic observation of instances of HCI practice form the empirical basis of the thesis. In addition, an analysis of some recorded human-computer interactions, which like the study as a whole, exemplifies an approach that differs from the prevailing sociological models within the field, is used to support the argument

Constraints to the Growth of Small Firms in Northern Myanmar

This paper uses survey data collected from Kalaymyo, a small urban city in North West Myanmar, to characterize firms and analyze the constraints limiting their growth. The level of firm ownership is very high but most firms are small, informal, operated out of the home, earning low income and with no employees. The most binding constraints are related to financing constraints, especially lack of access to informal credit. This is followed by the high degree of competition as the majority of firms are small retailers selling non-differentiated goods. This lack of credit combined with an apparent aversion to debt, limits the ability of entrepreneurs to take advantage of the high returns available on investment. We find that firms that made a capital investment over the last three years are significantly more profitable than those that did not

Mineral futures discussion paper: Sustainability issues, challenges and opportunities.

Minerals and metals will continue to play an important role in underpinning the future prosperity of our society. However, to confront the challenge of sustainability, the way in which resources are currently used, and might usefully be used in future, merits serious and broad discussion. This paper explores the background issues relating to mineral futures as a first step in the three-year research program of the Mineral Futures Collaboration Cluster – a collaborative program between the Australian CSIRO (Commonwealth Scientific Industrial Research Organisation); The University of Queensland; The University of Technology, Sydney; Curtin University of Technology; CQ University; and The Australian National University

The clinical effectiveness and cost-effectiveness of peginterferon alfa and ribavirin for the treatment of chronic hepatitis C in children and young people:a systematic review and economic evaluation

Background: Optimal therapy for children with chronic hepatitis C is unclear. Two treatment regimens are currently licensed in children. Objectives: To assess the clinical effectiveness and cost-effectiveness of peginterferon alfa-2a (Pegasys®, Roche) and peginterferon alfa-2b [ViraferonPeg®, Merck Sharp & Dohme (MSD)] in combination with ribavirin (RBV), within their licensed indications, for the treatment of chronic hepatitis C virus (HCV) in children and young people aged 3–17 years. Data sources: Twelve electronic bibliographic databases, including The Cochrane Library, MEDLINE and EMBASE, were searched from inception to November 2012. Bibliographies of retrieved papers, key hepatitis C websites and symposia and manufacturers’ submissions to the National Institute for Health and Care Excellence were also searched, and clinical experts were contacted. Review methods: Systematic reviews of clinical effectiveness and cost-effectiveness were conducted, including studies of health-related quality of life (HRQoL), following standard guidelines to ensure methodological rigour. Clinical effectiveness studies were included if they were in children and young people aged 3–17 years with chronic compensated HCV of any severity, including those with human immunodeficiency virus co-infection and those who were treatment naive or had been previously treated. Eligible interventions were peginterferon alfa-2a or peginterferon alfa-2b, each in combination with RBV, compared against best supportive care (BSC) or against each other, and study designs were randomised controlled trials (RCTs) or non-RCTs, or uncontrolled cohort studies. Outcomes included sustained virological response (SVR) and adverse events. Previously published Markov state-transition economic models of chronic HCV in adults were adapted to estimate the cost-effectiveness of peginterferon alfa-2a and -2b (in combination with RBV), compared with BSC and with one another in children. The model extrapolated the impact of SVR on life expectancy, quality-adjusted life expectancy and lifetime costs. Uncertainty was explored through probabilistic and deterministic sensitivity analyses. Results: Seven studies [two peginterferon alfa-2a and RBV (Copegus®, Roche), and five peginterferon alfa-2b and RBV (Rebetol®, MSD)] were included in the review of clinical effectiveness. Six were single-arm cohort studies and one was a RCT for which only those data for a single arm met the inclusion criteria. Overall, the studies were relatively small and of generally poor quality. SVR rates ranged from 53% to 66% (peginterferon alfa-2a) and 29% to 75% (peginterferon alfa-2b) (49% to 65% if excluding two studies with very small sample sizes). Rates of non-response and relapse were variable and adverse events were generally mild. No studies of cost-effectiveness or HRQoL in children and young people met the inclusion criteria. HRQoL, utilities and costs of treatment were therefore taken from studies of adults with chronic HCV. From this model, peginterferon alfa (-2a or -2b) in combination with RBV was more effective and had lower lifetime costs than BSC. Peginterferon alfa-2a had slightly lower lifetime costs and higher quality-adjusted life-years than peginterferon alfa-2b; therefore, peginterferon alfa-2b was dominated by peginterferon alfa-2a. Results were robust to changes in the sensitivity analyses. Limitations: There were few good quality studies and parameter data had to be taken from adult studies, which is a limitation of the work. Conclusions: Treatment of children and young people with peginterferon (alfa-2a or -2b) and RBV may be an effective therapy. Results from the independent Markov model suggest that peginterferon (alfa-2a or -2b) in combination with RBV is cost-effective compared with BSC. However, the available evidence is of poor quality. Future research into the impact of these treatments on growth and quality of life in children and young people is recommended. Study registration: This study is registered as PROSPERO CRD42012002743. Funding: The National Institute for Health Research Health Technology Assessment programme

Understanding how appraisal of doctors produces its effects: a realist review protocol

INTRODUCTION: UK doctors are now required to participate in revalidation to maintain their licence to practise. Appraisal is a fundamental component of revalidation. However, objective evidence of appraisal changing doctors' behaviour and directly resulting in improved patient care is limited. In particular, it is not clear how the process of appraisal is supposed to change doctors' behaviour and improve clinical performance. The aim of this research is to understand how and why appraisal of doctors is supposed to produce its effect. METHODS AND ANALYSIS: Realist review is a theory-driven interpretive approach to evidence synthesis. It applies realist logic of inquiry to produce an explanatory analysis of an intervention that is, what works, for whom, in what circumstances, in what respects. Using a realist review approach, an initial programme theory of appraisal will be developed by consulting with key stakeholders in doctors' appraisal in expert panels (ethical approval is not required), and by searching the literature to identify relevant existing theories. The search strategy will have a number of phases including a combination of: (1) electronic database searching, for example, EMBASE, MEDLINE, the Cochrane Library, ASSIA, (2) 'cited by' articles search, (3) citation searching, (4) contacting authors and (5) grey literature searching. The search for evidence will be iteratively extended and refocused as the review progresses. Studies will be included based on their ability to provide data that enable testing of the programme theory. Data extraction will be conducted, for example, by note taking and annotation at different review stages as is consistent with the realist approach. The evidence will be synthesised using realist logic to interrogate the final programme theory of the impact of appraisal on doctors' performance. The synthesis results will be written up according to RAMESES guidelines and disseminated through peer-reviewed publication and presentations. TRIAL REGISTRATION NUMBER: The protocol is registered with PROSPERO 2014:CRD42014007092.UK Department of HealthNational Institute for Health Research (NIHR