An Elastic Analysis of a Plated Bone to Determine Fracture Gap Motion

An elastic analysis to determine fracture gap motions occurring in the osteotomized and plated canine femur was performed using the finite element program NASTRAN. The femur was idealized as a hollow right cylinder, and transverse anisotropy was assumed for the elastic properties of the bone. A 3-D 360 degree model consisting of 224 isoparametric quadrilateral hexahedral and 11 beam elements was created. A range of plate stiffnesses was tested by varying the modulus of elasticity of the plate from 207 GPa to 1 GPA. Moments were applied in the plane of the plate, about the axis of the plate, and in the plane of the screws. Results showed that, for plates of typical geometry and elastic modulus under 10 GPa, the contribution to fracture gap motion occurring due to deformation in the bone was negligible compared to that contribution from deformation in the plate

Prediction of Critical Illness During Out-of-Hospital Emergency Care

CONTEXT: Early identification of nontrauma patients in need of critical care services in the emergency setting may improve triage decisions and facilitate regionalization of critical care. OBJECTIVES: To determine the out-of-hospital clinical predictors of critical illness and to characterize the performance of a simple score for out-of-hospital prediction of development of critical illness during hospitalization. DESIGN AND SETTING: Population-based cohort study of an emergency medical services (EMS) system in greater King County, Washington (excluding metropolitan Seattle), that transports to 16 receiving facilities. PATIENTS: Nontrauma, non-cardiac arrest adult patients transported to a hospital by King County EMS from 2002 through 2006. Eligible records with complete data (N = 144,913) were linked to hospital discharge data and randomly split into development (n = 87,266 [60%]) and validation (n = 57,647 [40%]) cohorts. MAIN OUTCOME MEASURE: Development of critical illness, defined as severe sepsis, delivery of mechanical ventilation, or death during hospitalization. RESULTS: Critical illness occurred during hospitalization in 5% of the development (n = 4835) and validation (n = 3121) cohorts. Multivariable predictors of critical illness included older age, lower systolic blood pressure, abnormal respiratory rate, lower Glasgow Coma Scale score, lower pulse oximetry, and nursing home residence during out-of-hospital care (P < .01 for all). When applying a summary critical illness prediction score to the validation cohort (range, 0-8), the area under the receiver operating characteristic curve was 0.77 (95% confidence interval [CI], 0.76-0.78), with satisfactory calibration slope (1.0). Using a score threshold of 4 or higher, sensitivity was 0.22 (95% CI, 0.20-0.23), specificity was 0.98 (95% CI, 0.98-0.98), positive likelihood ratio was 9.8 (95% CI, 8.9-10.6), and negative likelihood ratio was 0.80 (95% CI, 0.79- 0.82). A threshold of 1 or greater for critical illness improved sensitivity (0.98; 95% CI, 0.97-0.98) but reduced specificity (0.17; 95% CI, 0.17-0.17). CONCLUSIONS: In a population-based cohort, the score on a prediction rule using out-of-hospital factors was significantly associated with the development of critical illness during hospitalization. This score requires external validation in an independent populationPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/85143/1/Seymour - JAMA-2010-747-54.pdf11

Gyrotron experiments employing a field emission array cathode

The design and operation of a field emission array (FEA) cathode and the subsequent demonstration of the first FEA gyrotron are presented. Up to 10 mA from 30 000 tips was achieved reproducibly from each of ten chips in a gyrotron environment, namely, a vacuum 1 x 10(-8) mbar, -50 kV potential with multiple chip operation, The design parameters of the FEA gun were similar to those of a magnetron injection gun with an achievable electron beam current of 50-100 mA and measured power 720 W cw. Coherent microwave radiation was detected in both TE(02) at 30.1 GHz and TE(03) at 43.6 GHz, with a starting current of 1 mA

Kinetic Damage from Meteorites

Ballistic (kinetic energy) damage from falling meteorites has been recorded in two cases: the 1954 Sylacuga, Alabama meteorite of 4 kilogram mass which indirectly hit Ann Hodges and the 1992 Mbale meteorite fall where a 4 gram-sized meteorite struck a young boy. Neither event was fatal. Structures damaged by meteorites are much more common and include mail boxes (Figure 1) and cars (Figure2). Figure 3 shows that meteorite fragments of order 0.1 kilograms may cause serious human injury/fatality. Halliday et al (1985) estimated a human is struck once per decade by a meteorite (most likely gram-sized) while more than a dozen structures should be impacted annually by meteorite fragments

NASA-JSC antenna near-field measurement system

Work was completed on the near-field range control software. The capabilities of the data processing software were expanded with the addition of probe compensation. In addition, the user can process the measured data from the same computer terminal used for range control. The design of the laser metrology system was completed. It provides precise measruement of probe location during near-field measurements as well as position data for control of the translation beam and probe cart. A near-field range measurement system was designed, fabricated, and tested

Recommendations for HER2 testing in the UK

Determining the HER2 status of breast carcinomas is a prerequisite for the use of the monoclonal antibody trastuzumab (Herceptin(R)), which has recently been licensed for the treatment of metastatic disease. This necessitates a test based on archival material. The preferred analyses are immunohistochemistry with fluorescent in situ hybridisation (FISH) as a follow up test for ambiguous results. Guidelines have been developed for standardised, well controlled procedures for the provision of reliable results. A group of three reference laboratories has been established to provide advice, quality assurance, and materials, where needed

Characteristics of the 2012 Geminids

The parent of the Geminids, 3200 Phaethon, is a unique body in that it is classified as an asteroid, however is responsible for one of the most prolific meteor showers of the year and has shown comet-like behavior in its past (Jewitt and Li 2010). The Geminid meteor shower is also anomalous as its rates have been increasing since it was first detected. Understanding the composition and properties of meteoroids that belong to this meteor shower is an important area of study and of interest to both theoreticians and experimentalists. Using the light curve and decelerations of ten double-station Geminids as seen in the Meteoroid Environment Office's widefield meteor cameras, densities were able to be approximated using a model of meteoroid ablation by Campbell-Brown et al (2013) which employs thermal disruption to model the release of grains during ablation. Bulk densities of Geminids give unique insight into the composition of Phaethon that would only be derived by going to the asteroid itself. The bulk densities of these ten Geminids were found to be between 2.6 and 3.0 g/cm(3), supporting results from Babadzhanov (2009) and Borovicka et al (2010) which prove Phaethon has a much lower porosity than most other meteor shower parents. NASA's Meteoroid Environment Office established these two wide-field meteor cameras to observe meteors in the milligram-mass-range. Each camera consists of a 17 mm focal length Schneider lens (f/0.95) on a Watec 902U2 Ultimate CCD video camera, producing a 21.7x15.5 degree field-of-view. This configuration sees meteors down to a magnitude of +6. Data from these cameras are currently being used to calculate daily automated meteor fluxes. On the first night of operation, December 13-14, 2012, 18 double-station and 53 unique single-station Geminids were detected. The Geminid flux results from this system will be presented as well as ZHR's over the peak of the Geminids. The average flux density over the night was 0.058, 0.052, and 0.062 meteors/km(2)/hour down to a limiting magnitude of +6.5, for the double-station results and each single-station's results. This equates to ZHR's of 113, 102, and 122 respectively. Included in the flux algorithm is a process to find the collecting area per height and a method to find the limiting meteor magnitude per 10 minute time period

Influence of Spin Wave Excitations on the Ferromagnetic Phase Diagram in the Hubbard-Model

The subject of the present paper is the theoretical description of collective electronic excitations, i.e. spin waves, in the Hubbard-model. Starting with the widely used Random-Phase-Approximation, which combines Hartree-Fock theory with the summation of the two-particle ladder, we extend the theory to a more sophisticated single particle approximation, namely the Spectral-Density-Ansatz. Doing so we have to introduce a `screened` Coulomb-interaction rather than the bare Hubbard-interaction in order to obtain physically reasonable spinwave dispersions. The discussion following the technical procedure shows that comparison of standard RPA with our new approximation reduces the occurrence of a ferromagnetic phase further with respect to the phase-diagrams delivered by the single particle theories.Comment: 8 pages, 9 figures, RevTex4, accepted for publication in Phys. Rev.