35,406 research outputs found
Testing a Simplified Version of Einstein's Equations for Numerical Relativity
Solving dynamical problems in general relativity requires the full machinery
of numerical relativity. Wilson has proposed a simpler but approximate scheme
for systems near equilibrium, like binary neutron stars. We test the scheme on
isolated, rapidly rotating, relativistic stars. Since these objects are in
equilibrium, it is crucial that the approximation work well if we are to
believe its predictions for more complicated systems like binaries. Our results
are very encouraging.Comment: 9 pages (RevTeX 3.0 with 6 uuencoded figures), CRSR-107
Henri Temianka Correspondence; (lte)
This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3175/thumbnail.jp
A questionnaire elicitation of surgeons' belief about learning within a surgical trial
PMID: 23145113 [PubMed - indexed for MEDLINE] PMCID: PMC3493499 Free PMC ArticlePeer reviewedPublisher PD
Different populations of RNA polymerase II in living mammalian cells
RNA polymerase II is responsible for transcription of most eukaryotic genes, but, despite exhaustive analysis, little is known about how it transcribes natural templates in vivo. We studied polymerase dynamics in living Chinese hamster ovary cells using an established line that expresses the largest (catalytic) subunit of the polymerase (RPB1) tagged with the green fluorescent protein (GFP). Genetic complementation has shown this tagged polymerase to be fully functional. Fluorescence loss in photobleaching (FLIP) reveals the existence of at least three kinetic populations of tagged polymerase: a large rapidly-exchanging population, a small fraction resistant to 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) but sensitive to a different inhibitor of transcription (i.e. heat shock), and a third fraction sensitive to both inhibitors. Quantitative immunoblotting shows the largest fraction to be the inactive hypophosphorylated form of the polymerase (i.e. IIA). Results are consistent with the second (DRB-insensitive but heat-shock-sensitive) fraction being bound but not engaged, while the third (sensitive to both DRB and heat shock) is the elongating hyperphosphorylated form (i.e. IIO)
Graphic simualtion test bed for robotics applications in a workstation environment
Graphical simulation is a cost-effective solution for developing and testing robots and their control systems. The availability of various high-performance workstations makes these systems feasible. Simulation offers preliminary testing of systems before their actual realizations, and it provides a framework for developing new control and planning algorithms. On the other hand, these simulation systems have to have the capability of incorporating various knowledge-based system components, e.g., task planners, representation formalisms, etc. They also should have an appropriate user interface, which makes possible the creation and control of simulation models. ROBOSIM was developed jointly by MSFC and Vanderbilt University, first in a VAX environment. Recently, the system has been ported to an HP-9000 workstation equipped with an SRX graphics accelerator. The user interface of the system now contains a menu- and icon-based facility, as well as the original ROBOSIM language. The system is also coupled to a symbolic computing system based on Common Lisp, where knowledge-based functionalities are implemented. The knowledge-based layer uses various representation and reasoning facilities for programming and testing the control systems of robots
Ecological Effects of Fear: How Spatiotemporal Heterogeneity in Predation Risk Influences Mule Deer Access to Forage in a Sky‐Island System
Forage availability and predation risk interact to affect habitat use of ungulates across many biomes. Within sky‐island habitats of the Mojave Desert, increased availability of diverse forage and cover may provide ungulates with unique opportunities to extend nutrient uptake and/or to mitigate predation risk. We addressed whether habitat use and foraging patterns of female mule deer (Odocoileus hemionus) responded to normalized difference vegetation index (NDVI), NDVI rate of change (green‐up), or the occurrence of cougars (Puma concolor). Female mule deer used available green‐up primarily in spring, although growing vegetation was available during other seasons. Mule deer and cougar shared similar habitat all year, and our models indicated cougars had a consistent, negative effect on mule deer access to growing vegetation, particularly in summer when cougar occurrence became concentrated at higher elevations. A seemingly late parturition date coincided with diminishing NDVI during the lactation period. Sky‐island populations, rarely studied, provide the opportunity to determine how mule deer respond to growing foliage along steep elevation and vegetation gradients when trapped with their predators and seasonally limited by aridity. Our findings indicate that fear of predation may restrict access to the forage resources found in sky islands
Ground-State and Domain-Wall Energies in the Spin-Glass Region of the 2D Random-Bond Ising Model
The statistics of the ground-state and domain-wall energies for the
two-dimensional random-bond Ising model on square lattices with independent,
identically distributed bonds of probability of and of
are studied. We are able to consider large samples of up to
spins by using sophisticated matching algorithms. We study
systems, but we also consider samples, for different aspect ratios
. We find that the scaling behavior of the ground-state energy and
its sample-to-sample fluctuations inside the spin-glass region () are characterized by simple scaling functions. In particular, the
fluctuations exhibit a cusp-like singularity at . Inside the spin-glass
region the average domain-wall energy converges to a finite nonzero value as
the sample size becomes infinite, holding fixed. Here, large finite-size
effects are visible, which can be explained for all by a single exponent
, provided higher-order corrections to scaling are included.
Finally, we confirm the validity of aspect-ratio scaling for : the
distribution of the domain-wall energies converges to a Gaussian for ,
although the domain walls of neighboring subsystems of size are
not independent.Comment: 11 pages with 15 figures, extensively revise
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Reducing weight and increasing physical activity in people at high risk of cardiovascular disease: a randomised controlled trial comparing the effectiveness of enhanced motivational interviewing intervention with usual care.
OBJECTIVE: The epidemic of obesity is contributing to the increasing prevalence of people at high risk of cardiovascular disease (CVD), negating the medical advances in reducing CVD mortality. We compared the clinical and cost-effectiveness of an intensive lifestyle intervention consisting of enhanced motivational interviewing in reducing weight and increasing physical activity for patients at high risk of CVD. METHODS: A three-arm, single-blind, parallel-group randomised controlled trial was conducted in consenting primary care centres in south London. We recruited patients aged 40-74 years with a QRisk2 score ≥20.0%, which indicates the probability of having a CVD event in the next 10 years. The intervention was enhanced motivational interviewing which included additional behaviour change techniques and was delivered by health trainers in 10 sessions over 1 year, in either group (n=697) or individual (n=523) format. The third arm received usual care (UC; n=522). The primary outcomes were physical activity (mean steps/day) and weight (kg). Secondary outcomes were changes in low-density lipoprotein cholesterol and CVD risk score. We estimated the relative cost-effectiveness of each intervention. RESULTS: At 24 months, the group and individual interventions were not more effective than UC in increasing physical activity (mean difference=70.05 steps, 95% CI -288.00 to 147.90 and mean difference=7.24 steps, 95% CI -224.01 to 238.50, respectively), reducing weight (mean difference=-0.03 kg, 95% CI -0.49 to 0.44 and mean difference=-0.42 kg, 95% CI -0.93 to 0.09, respectively) or improving any secondary outcomes. The group and individual interventions were not cost-effective at conventional thresholds. CONCLUSIONS: Enhancing motivational interviewing with additional behaviour change techniques was not effective in reducing weight or increasing physical activity in those at high CVD risk
The Composite Face Illusion
Few findings in cognitive science have proved as influential as the composite face effect. When the top half of one face is aligned with the bottom half of another, and presented upright, the resulting composite arrangement induces a compelling percept of a novel facial configuration. Findings obtained using composite face procedures have contributed significantly to our understanding of holistic face processing, the detrimental effects of face inversion, the development of face perception, and aberrant face perception in clinical populations. Composite paradigms continue to advance our knowledge of face perception, as exemplified by their recent use for investigating the perceptual mechanisms underlying dynamic face processing. However, the paradigm has been the subject of intense scrutiny, particularly over the last decade, and there is a growing sense that the composite face illusion, whilst easy to illustrate, is deceptively difficult to measure and interpret. In this review we provide a focussed overview of the existing composite face literature, and identify six priorities for future research. Addressing these gaps in our knowledge will aid the evaluation and refinement of theoretical accounts of the illusion
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