2,152 research outputs found

    Informal boundary-spanning links and networks in successful technological innovation

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    The sources of ideas embodied within successful technological innovation has been a subject of interest in many studies since the 1950s. This research suggests that sources external to the innovating organisation account for between one and two-thirds of the inputs important to the innovation process. In addition, studies have long highlighted the important role played by the personal boundary-spanning relationships of engineers and scientists as a channel for the transference of such inputs. However, research concerning the role and nature of personal boundary-spanning links in the innovation process have either been primarily structurally orientated, seeking to map out the informal networks of scientists and engineers, or more typically, anecdotal. The objective of this research was to reveal and build upon our knowledge of the role, nature and importance of informal exchange activity in the innovation process. In order to achieve this, an empirical study was undertaken to determine the informal sources, channels and mechanisms employed in the development of thirty five award-winning innovations. Through the adoption of the network perspective, the multiple sources and pluralistic patterns of collaboration and communication in the innovation process were systematically explored. This approach provided a framework that allowed for the detailed study of both the individual dyadic links and morphology of the innovation action-sets in which these dyads were embedded. The research found, for example, that the mobilisation of boundary-spanning links and networks was an important or critical factor in nineteen (54%) of the development projects. Of these, informal boundary-spanning exchange activity was considered to be important or critical in eight (23%)

    The effect of modular tapered fluted stems on proximal stress shielding in the human femur.

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    Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of radiographs or other medical imaging techniques. The effect of modular systems using tapered fluted stems on proximal stress shielding in the human femur is the focus of this study. Seven modular implants were press-fit into seven femurs, where there was little or no contact between the modular body and the test femur. Finally, hydroxyapatite bone cement was added to create an interface between the modular body and femur. Stress shielding is perhaps one of the most critical complications that occur after total hip arthroplasty (THA). Insertion of the prosthesis permanently alters the stress distribution in the human femur. Stress shielding occurs in those areas in which a bone experiences a reduction of stress. Essentially, the prosthesis shields the stress from the bone by transmitting the force through the implant rather than the bone, which can lead to a decrease in bone mineral density due to the reduction of stress or failure of the implant itself. Seven test femurs were instrumented with strain gages to measure the strain at three different levels. Two loading conditions were applied to represent the forces exerted on the femur when a human is in a natural standing position. The loading conditions were applied to the intact femur: when the prosthesis was inserted into the femur with a press-fit; and when hydroxyapatite bone cement was injected around the implant in the proximal region. All femurs exhibited stress shielding effects after surgically inserting the modular implants. The experimental data confirmed that the greatest amount of stress shielding occurred primarily in the proximal and mid-stem regions. The strains at the junction between the modular body and stem were relatively low. The experimental data also confirmed that with the addition of BoneSource® Hydroxyapatite cement the strain in the proximal and mid-stem regions significantly increased, but stress shielding still occurred. The strains at the junction between the body and stem also decreased

    Mechanical and electrical characterisation of Au wire interconnects in electronic packages under the combined vibration and thermal testing conditions

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    This paper concerns the reliability of thermosonically bonded 25μm Au wires in the combined high temperature with vibration conditions, under which the tests have been carried out on wire bonded 40-pin Dual-in-Line (DIL) High Temperature Co-fired Ceramic (HTCC) electronic packages. Mechanical, optical and electrical analysis has been undertaken in order to identify the failure mechanisms of bonded wires due to the combined testing. The results indicated a decrease in the electrical resistance after a few hours of testing as a result of the annealing process of the Au wire during testing. Shear and pull strength levels remained high in general after testing, showing no significant deterioration due to the test under the combined high temperature and vibration conditions. However, a trend of the variation in the strength values is identified with respect to the combined conditions for all wire bonded packages, which may be summarised as: i) increase of the testing temperature has led to a decrease of both the shear and pull strength of the wire bonds; ii) the mechanical behaviour of the wires is affected due to crystallization that leads to material softening and consequently the deformation of wire

    Family memories in the home: contrasting physical and digital mementos

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    We carried out fieldwork to characterise and compare physical and digital mementos in the home. Physical mementos are highly valued, heterogeneous and support different types of recollection. Contrary to expectations, we found physical mementos are not purely representational, and can involve appropriating common objects and more idiosyncratic forms. In contrast, digital mementos were initially perceived as less valuable, although participants later reconsidered this. Digital mementos were somewhat limited in function and expression, largely involving representational photos and videos, and infrequently accessed. We explain these digital limitations and conclude with design guidelines for digital mementos, including better techniques for accessing and integrating these into everyday life, allowing them to acquire the symbolic associations and lasting value that characterise their physical counterparts

    Phonologic Rehabilitation of Anomia in Aphasia

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    The single most common feature of aphasia is impairment in ability to name, whether it involves naming seen objects, or producing nouns, verbs and other words conveying meaning in spontaneous language. The traditional treatment approach to this problem is to explicitly train aphasic patients in naming. Controlled studies have shown that this approach may be quite effective. However, typically generalization is very limited, that is, the knowledge gained by the patient tends to be limited to the words actually trained, and there is at best very modest improvement in performance with untrained words (limited mainly to those that are semantically related to the trained words). Because generalization is can be limited with this approach, there currently exists no viable means of training patients on the full corpus of words (perhaps several thousand) they are likely to need in daily life. Two approaches might be taken to solving this problem: 1) develop cost effective means for providing training on several thousand words; and 2) develop alternative training methods, e.g., phonological therapy, that potentially could intrinsically generalize widely. The focus of this proposal is the second of these two approaches. Thus, the primary purpose of this Phase II clinical rehabilitation study was to examine the effect of a phonologic based treatment on confrontation naming by individuals with anomic aphasia. We used a single-subject ABA design replicated across ten participants. The primary research question asked if phonologic treatment would improve confrontation naming. Secondary research questions addressed the impact of treatment on 1) generalization to untrained behaviors such as discourse production; 2) retention effects at 3-months; 3) phonologic production and 4) nonword repetition (potential evidence of phoneme sequence knowledge acquisition)

    Same words, different worlds: Exploring differences in researcher and participant understandings of promise and obligation in the psychological contract

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    This paper addresses long-standing questions about promise and obligation, two of the key conceptual building blocks for psychological contract research, are conceptualized and operationalized: How do employees understand these concepts? Would their understandings be congruent with the researchers’ and how would this knowledge inform future psychological contract research? Drawing on interviews with Chinese workers from diverse backgrounds, our results suggest the concepts have distinct meanings for participants in terms of three criteria (defining characteristics, key features and manifestations in employment). We argue that promise and obligation are likely to serve different functions in employment relationship and have different meanings for researchers versus participants, and accordingly we highlight the challenges of using them to conceptualize and operationalize psychological contracts in China and beyond

    Validated respiratory drug deposition predictions from 2D and 3D medical images with statistical shape models and convolutional neural networks

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    For the one billion sufferers of respiratory disease, managing their disease with inhalers crucially influences their quality of life. Generic treatment plans could be improved with the aid of computational models that account for patient-specific features such as breathing pattern, lung pathology and morphology. Therefore, we aim to develop and validate an automated computational framework for patient-specific deposition modelling. To that end, an image processing approach is proposed that could produce 3D patient respiratory geometries from 2D chest X-rays and 3D CT images. We evaluated the airway and lung morphology produced by our image processing framework, and assessed deposition compared to in vivo data. The 2D-to-3D image processing reproduces airway diameter to 9% median error compared to ground truth segmentations, but is sensitive to outliers of up to 33% due to lung outline noise. Predicted regional deposition gave 5% median error compared to in vivo measurements. The proposed framework is capable of providing patient-specific deposition measurements for varying treatments, to determine which treatment would best satisfy the needs imposed by each patient (such as disease and lung/airway morphology). Integration of patient-specific modelling into clinical practice as an additional decision-making tool could optimise treatment plans and lower the burden of respiratory diseases.</p
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