2,631 research outputs found
Ethical Leadership in Kazakhstan: An Exploratory Study
This study measured ethical leadership perceptions utilizing a new corporate culture scale in a Central Asian country. Ethical leadership ratings from 103 Kazakhstani employees were used to determine how they perceived their managers in terms of being moral people and moral managers. Results indicate that managers are perceived as relatively weaker moral managers as compared to moral persons. Holding employees accountable for their actions is the lowest rated aspect of the moral manager. Definitions of moral persons and moral managers in Kazakhstan vary somewhat from an American culture-oriented ethical leadership model. Implications for theory and practice are discussed
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Evolution of a transdisciplinary "One Medicine-One Health" approach to global health education at the University of California, Davis.
In today's world health events in one nation or geographic area often have repercussions for the health and well-being of populations beyond that region; sometimes even globally. In recent years many factors, most notably concern about emerging infectious diseases, have contributed to an increasing appreciation of the interdependency of human, animal and ecosystem health worldwide. Integrated global approaches to improve the health of humans, animals and their shared environments are proving to be in the best interest of many countries. A special symposium and award were established in memoriam to the internationally renowned epidemiologist, Dr. Calvin W. Schwabe, who (while at the University of California, Davis) was a significant advocate of the "One Medicine" approach to public health, calling upon all health professionals, including veterinarians, to work collaboratively and comparatively to improve human health. This paper discusses the evolution of the "One Medicine" concept into a global "One Health" approach to research, training capacity and service infrastructure, focused not only on disease, but also on health at the individual, population, and ecosystem levels. Projects involving UCD faculty which attempt to integrate a One Health approach include the Health for Animals and Livelihood Improvement (HALI) Project in Tanzania, Envirovet Summer Institute, Avian Flu School and Newcastle Immunization Program in Africa, a web-based virtual global health training program, and the Calvin Schwabe One Health Project
The Beacon Calculus: A formal method for the flexible and concise modelling of biological systems.
Biological systems are made up of components that change their actions (and interactions) over time and coordinate with other components nearby. Together with a large state space, the complexity of this behaviour can make it difficult to create concise mathematical models that can be easily extended or modified. This paper introduces the Beacon Calculus, a process algebra designed to simplify the task of modelling interacting biological components. Its breadth is demonstrated by creating models of DNA replication dynamics, the gene expression dynamics in response to DNA methylation damage, and a multisite phosphorylation switch. The flexibility of these models is shown by adapting the DNA replication model to further include two topics of interest from the literature: cooperative origin firing and replication fork barriers. The Beacon Calculus is supported with the open-source simulator bcs (https://github.com/MBoemo/bcs.git) to allow users to develop and simulate their own models
Rare manifestation of a c.290 C\u3eT, p.Gly97Glu VCP mutation
Introduction. The valosin-containing protein (VCP) regulates several distinct cellular processes. Consistent with this, VCP mutations manifest variable clinical phenotypes among and within families and are a diagnostic challenge. Methods. A 60-year-old man who played ice hockey into his 50’s was evaluated by electrodiagnostics, muscle biopsy, and molecular genetics. Results. With long-standing pes cavus and toe walking, our patient developed progressive weakness, cramps, memory loss, and paresthesias at age 52. An axonal sensorimotor neuropathy was found upon repeated testing at age 58. Neuropathic histopathology was present in the quadriceps, and exome sequencing revealed the VCP mutation c.290 C>T, p.Gly97Glu. Conclusions. Our patient reflects the clinical heterogeneity of VCP mutations, as his neurological localization is a spectrum between a lower motor neuron disorder and a hereditary axonal peripheral neuropathy such as CMT2. Our case demonstrates a rare manifestation of the c.290 C>T, pGly97Glu VCP mutation
Detection of Rotational Spectral Variation on the M-type asteroid (16) Psyche
The asteroid (16) Psyche is of scientific interest because it contains ~ 1%
of the total mass of the asteroid belt and is thought to be the remnant
metallic core of a protoplanet. Radar observations have indicated the
significant presence of metal on the surface with a small percentage of
silicates. Prior ground-based observations showed rotational variations in the
near-infrared (NIR) spectra and radar albedo of this asteroid. However, no
comprehensive study that combines multi-wavelength data has been conducted so
far. Here we present rotationally resolved NIR spectra (0.7-2.5 microns) of
(16) Psyche obtained with the NASA Infrared Telescope Facility. These data have
been combined with shape models of the asteroid for each rotation phase.
Spectral band parameters extracted from the NIR spectra show that the pyroxene
band center varies from ~ 0.92 to 0.94 microns. Band center values were used to
calculate the pyroxene chemistry of the asteroid, whose average value was found
to be Fs30En65Wo5. Variations in the band depth were also observed, with values
ranging from 1.0 to 1.5%. Using a new laboratory spectral calibration we
estimated an average orthopyroxene content of 6+/-1%. The mass-deficit region
of Psyche, which exhibits the highest radar albedo, also shows the highest
value for spectral slope and the minimum band depth. The spectral
characteristics of Psyche suggest that its parent body did not have the typical
structure expected for a differentiated body or that the sequence of events
that led to its current state was more complex than previously thought.Comment: 21 pages, 8 figures, 2 tables, published in The Astronomical Journa
Technical Skill Assessments as a Predictor or Agriculture Students\u27 Success after High School
This study was conducted using quantitative methods to determine if a relationship exists between former Agriculture Career and Technical Education (CTE) concentrators’ Technical Skills Assessment (TSA) performance and their attaining related placement after high school. The study included data from 13,581 agriculture students who graduated during the years 2015-2019. To investigate the relationship between TSA assessment performance and attaining related placement, multiple descriptive models were run and disaggregated by gender, race/ethnicity, Individuals Education Plan (IEP) status, and Socioeconomic Status (SES). The data revealed students who pass their TSA assessment are more likely to attain related placement compared to those not passing their assessment. Agriculture students’ rates of passing the TSA assessment and attaining related placement were high. Additional analysis to determine the relationship between TSA assessment performance and attaining related placement involved multiple binary logistic regression models. The logistic regression models helped determine how passing the TSA assessment and student demographics interacted and influenced students attaining related placement. Statistically significant findings were determined for TSA assessment, Black students, and those not disadvantaged in the SES category. The findings from this study may add merit to the numerous secondary CTE agriculture education programs in the United States.
Keywords: Agriculture education, technical skill assessment, CTE accountability measures, industry-recognized credentia
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Spatial epidemiological patterns suggest mechanisms of land-sea transmission for Sarcocystis neurona in a coastal marine mammal.
Sarcocystis neurona was recognised as an important cause of mortality in southern sea otters (Enhydra lutris nereis) after an outbreak in April 2004 and has since been detected in many marine mammal species in the Northeast Pacific Ocean. Risk of S. neurona exposure in sea otters is associated with consumption of clams and soft-sediment prey and is temporally associated with runoff events. We examined the spatial distribution of S. neurona exposure risk based on serum antibody testing and assessed risk factors for exposure in animals from California, Washington, British Columbia and Alaska. Significant spatial clustering of seropositive animals was observed in California and Washington, compared with British Columbia and Alaska. Adult males were at greatest risk for exposure to S. neurona, and there were strong associations with terrestrial features (wetlands, cropland, high human housing-unit density). In California, habitats containing soft sediment exhibited greater risk than hard substrate or kelp beds. Consuming a diet rich in clams was also associated with increased exposure risk. These findings suggest a transmission pathway analogous to that described for Toxoplasma gondii, with infectious stages traveling in freshwater runoff and being concentrated in particular locations by marine habitat features, ocean physical processes, and invertebrate bioconcentration
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