Embodied cognition in robots and human evolution

Thesis (S.M. in Science Writing)--Massachusetts Institute of Technology, Dept. of Humanities, Graduate Program in Science Writing, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 44).This thesis investigates the notion of embodied cognition in humans using the research of former University of Washington researcher William Calvin and robots using the research of former MIT professor Rodney Brooks. The idea is that the feedback from the physicality of humans is a precognition to our intelligence. The choice example I use for our physicality is the motion of throwing, particularly the javelin throw. For robotics, I focus on the development of 'eyes' in Brooks' robot Cog and show how it demonstrated behavior we deem to be intelligent using the feedback gleaned from 'seeing'. Altogether, I present evidence for and against the notion that we are who we are, cognitively speaking, because of the sensory feedback of our physical bodies, and what that may mean going forward in the future for our intelligence.by Conor L. Myhrvold.S.M.in Science Writin

Flesh and Circuit: Rethinking Performance and Technology

The live, embodied, material, and interactive qualities of performance have made it a notable means of exploring the creative potential of technological engagement, acting as a critical vector for revealing and resisting the technological colonisation of everyday life. The innovative collaborations of Experiments in Art and Technology (EAT) during the 1960’s with artists such as Yvonne Rainer and Robert Rauschenberg, Stelarc’s extreme body modifications, Dumb Type’s intermedia performance, and Guillermo Gomez-Pena and La Pocha Nostra’s poetic and speculative imaginings, have mapped the advances in technology and opened new creative fields to explore embodiment. However, there are still some significant oversights in regard to the pervasive and intimate nature of technological mediation, surveillance, and behavioural modification. Currently, technological embodiment assumes new forms tied to data assemblages of unprecedented scope and granularity. The body is commodified as data to be exchanged, controlled, and influenced in algorithmic regimes of governance and as raw material for machine learning and AI. Artists working with performance and technology are engaging with these exclusions, rethinking the intersection of performance and technology, and re-defining embodiment for the twenty-first century. The following articles start to fill these gaps in the literature on art, technology and embodiment through the lens of performance. While much remains to be written on the topic to account for current artistic practice and the changing nature of digital platforms and ubiquity of algorithmic governance, these articles point to new ways of thinking on issues around the intersections of flesh and circuits

Rapid iododeboronation with and without gold catalysis: application to radiolabelling of arenes

Radiopharmaceuticals incorporating radioactive iodine in combination with SPECT imaging play a key role in nuclear medicine, with applications in drug development and disease diagnosis. Despite this importance, there are relatively few general methods for incorporating radioiodine into small molecules. Here we describe a rapid, air- and moisture-stable ipso-iododeboronation procedure using NIS, in the non-toxic and green solvent dimethyl carbonate. The fast reaction and mild conditions of the gold-catalysed method led to the development of a highly efficient process for radiolabelling of arenes, which constitutes the first example of an application of homogenous gold catalysis to selective radiosynthesis. This has been exemplified with an effective synthesis of radiolabelled meta-[125I]iodobenzylguanidine, a radiopharmaceutical used for the imaging and therapy of human norepinephrine transporter-expressing tumours

Management of postoperative ileus: focus on alvimopan

Postoperative ileus (POI) is a transient loss of coordinated peristalsis precipitated by surgery and exacerbated by opioid pain medication. Ileus causes a variety of symptoms including bloating, pain, nausea, and vomiting, but particularly delays tolerance of oral diet and liquids. Thus POI is a primary determinant of hospital stay after surgery. ‘Fast-track’ recovery protocols, opioid sparing analgesia, and laparoscopic surgery reduce but do not eliminate postoperative ileus. Alvimopan is a mu opioid receptor antagonist that blocks the effects of opioids on the intestine, while not interfering with their centrally mediated analgesic effect. Several large randomized clinical trials have demonstrated that alvimopan accelerates the return of gastrointestinal function after surgery and subsequent hospital discharge by approximately 20 hours after elective open segmental colectomy. However, it has not been tested in patients undergoing laparoscopic surgery and is less effective in patients receiving nonsteroidal anti-inflammatory agents in a narcotic sparing postoperative pain control regimen. Safety concerns seen with chronic low dose administration of alvimopan for opioid bowel dysfunction have not been noted with its acute use for POI

Examining the Effects of Variation in Emotional Tone of Voice on Spoken Word Recognition

Emotional tone of voice (ETV) is essential for optimal verbal communication. Research has found that the impact of variation in nonlinguistic features of speech on spoken word recognition differs according to a time course. In the current study, we investigated whether intratalker variation in ETV follows the same time course in two long-term repetition priming experiments. We found that intratalker variability in ETVs affected reaction times to spoken words only when processing was relatively slow and difficult, not when processing was relatively fast and easy. These results provide evidence for the use of both abstract and episodic lexical representations for processing within-talker variability in ETV, depending on the time course of spoken word recognition

Experimental chronic noise is related to elevated fecal corticosteroid metabolites in lekking male greater Sage-Grouse (Centrocercus urophasianus).

There is increasing evidence that individuals in many species avoid areas exposed to chronic anthropogenic noise, but the impact of noise on those who remain in these habitats is unclear. One potential impact is chronic physiological stress, which can affect disease resistance, survival and reproductive success. Previous studies have found evidence of elevated stress-related hormones (glucocorticoids) in wildlife exposed to human activities, but the impacts of noise alone are difficult to separate from confounding factors. Here we used an experimental playback study to isolate the impacts of noise from industrial activity (natural gas drilling and road noise) on glucocorticoid levels in greater sage-grouse (Centrocercus urophasianus), a species of conservation concern. We non-invasively measured immunoreactive corticosterone metabolites from fecal samples (FCMs) of males on both noise-treated and control leks (display grounds) in two breeding seasons. We found strong support for an impact of noise playback on stress levels, with 16.7% higher mean FCM levels in samples from noise leks compared with samples from paired control leks. Taken together with results from a previous study finding declines in male lek attendance in response to noise playbacks, these results suggest that chronic noise pollution can cause greater sage-grouse to avoid otherwise suitable habitat, and can cause elevated stress levels in the birds who remain in noisy areas

Readily accessible sp3-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality

Increased molecular complexity correlates with improved chances of success in the drug development process. Here, a strategy for the creation of sp3-rich, non-planar heterocyclic scaffolds suitable for drug discovery is described that obviates the need to generate multiple stereogenic centers with independent control. Asymmetric transfer hydrogenation using a tethered Ru-catalyst is used to efficiently produce a range of enantiopure cyclic hydrazine building blocks (up to 99% ee). Iterative C–N functionalization at the two nitrogen atoms of these compounds produces novel hydrazine and hydrazide based chemical libraries. Wide chemical diversification is possible through variation in the hydrazine structure, use of different functionalization chemistries and coupling partners, and controlled engagement of each nitrogen of the hydrazine in turn. Principal Moment of Inertia (PMI) analysis of this small hydrazine library reveals excellent shape diversity and three-dimensionality. NMR and crystallographic studies confirm these frameworks prefer to orient their substituents in three-dimensional space under the control of a single stereogenic center through exploitation of the fluxional behavior of the two nitrogen atoms

RR Lyrae Variables in Two Fields in the Spheroid of M31

We present Hubble Space Telescope observations taken with the Advanced Camera for Surveys Wide Field Channel of two fields near M32—between 4 and 6 kpc from the center of M31. The data cover a time baseline sufficient for the identification and characterization of 681 RR Lyrae variables of which 555 are ab-type and 126 are c-type. The mean magnitude of these stars is = 25.29 ± 0.05, where the uncertainty combines both the random and systematic errors. The location of the stars in the Bailey diagram and the ratio of c-type RR Lyraes to all types are both closer to RR Lyraes in Oosterhoff type I globular clusters in the Milky Way as compared with Oosterhoff II clusters. The mean periods of the ab-type and c-type RR Lyraes are = 0.557 ± 0.003 and = 0.327 ± 0.003, respectively, where the uncertainties in each case represent the standard error of the mean. When the periods and amplitudes of the ab-type RR Lyraes in our sample are interpreted in terms of metallicity, we find the metallicity distribution function to be indistinguishable from a Gaussian with a peak at = –1.50 ± 0.02, where the quoted uncertainty is the standard error of the mean. Using a relation between RR Lyrae luminosity and metallicity along with a reddening of E(B – V) = 0.08 ± 0.03, we find a distance modulus of (m – M)_0 = 24.46 ± 0.11 for M31. We examine the radial metallicity gradient in the environs of M31 using published values for the bulge and halo of M31 as well as the abundances of its dwarf spheroidal companions and globular clusters. In this context, we conclude that the RR Lyraes in our two fields are more likely to be halo objects rather than associated with the bulge or disk of M31, in spite of the fact that they are located at 4-6 kpc in projected distance from the center