273 research outputs found
Nurses\u27 Alumnae Association Bulletin, September 1958
Committee Reports
Digest of Alumnae Meetings
Graduation Awards - 1957
List of Wrong Addresses
Marriages
Necrology
New Arrivals
Physical Advances at Jefferson
President\u27s Message
School of Nursing Repor
Nurses\u27 Alumnae Association Bulletin, May 1960
Accreditation of Programs in Nursing
Alumnae Meetings, 1959
Committee Reports
Greetings from the President
Highlights from first issue of Alumnae Bulletin
Living in the new nurses residence
Lost Members
Marriages
Necrology
New Arrivals
Notices
Personal Items of Interest
Report of the School of Nursing and Nursing Services
Staff Nurses Association
Student Activities
Year of tremendous growth and expansio
A survey of educational articles appearing in sixteen popular magazines for an eleven year period from January, 1943 through December, 1953.
Thesis (Ed.M.)--Boston Universit
Nurses\u27 Alumnae Association Bulletin, April 1959
Alumnae News
Anniversary Class of /34
Article from Pennsylvania Nurse
Committee Reports
Current Events at Jefferson
Greetings from the President
Jefferson Story
Lost Members
Letter - Past President
Marriages
Necrology
New Arrivals
Notices
Pictured - Student Nurses\u27 Residence
Report of the School of Nursing and Nursing Services
Staff Nurses Social Functions
Student Activities
Voluntary Service
Year of Great Activity and Expansio
An Evening Sector Ps 6 - Omega Band Event
Article draft. Author list indicative and roughly corresponds to amount of contribution to the article to date.Abstract. Ps 6 magnetic disturbances and associated optical
forms known as omega bands are usually associated
with the morning sector. Some evidence for similar phenomenology
in the evening sector has been presented by
Solovyev et al. (1999). We confirm and extend those results
with high time resolution magnetic and imaging observations
from Athabasca University Geophysical Observatory
for an event that took place on July 27, 2003, along with conjugate
hemisphere imaging from the Polar spacecraft. The
observed signatures indicate sunward drift (westward in the
evening sector). Magnetic perturbations feature negative Y
and transitional Z indicating westward passage of poleward
equivalent currents overhead. As has been suggested by Connors
et al. (2003) to be often the case for morning sector Ps
6/omega bands, initiation of the evening sector event coincided
with substorm onset. From optical and magnetic data
we obtain consistent results for the drift rate of the forms,
which changed during the event. An inner magnetospheric
source is suggested, with triggering of the onset by an increase
in solar wind speed
Kisspeptin, neurokinin B, and dynorphin cct in the arcuate nucleus to control activity of the GnRH pulse generator in Ewes
Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy) neurons in
the arcuate nucleus play a key role in GnRH pulse generation, with kisspeptin driving GnRH release
and neurokinin B (NKB) and dynorphin acting as start and stop signals, respectively. In this study,
we tested this hypothesis by determining the actions, if any, of four neurotransmitters found in
KNDy neurons (kisspeptin, NKB, dynorphin, and glutamate) on episodic LH secretion using local
administration of agonists and antagonists to receptors for these transmitters in ovariectomized
ewes. We also obtained evidence that GnRH-containing afferents contact KNDy neurons, so we
tested the role of two components of these afferents: GnRH and orphanin-FQ. Microimplants of
a Kiss1r antagonist briefly inhibited LH pulses and microinjections of 2 nmol of this antagonist
produced a modest transitory decrease in LH pulse frequency. An antagonist to the NKB receptor
also decreased LH pulse frequency, whereas NKB and an antagonist to the receptor for dynorphin
both increased pulse frequency. In contrast, antagonists toGnRHreceptors, orphanin-FQ receptors,
and the N-methyl-D-aspartate glutamate receptor had no effect on episodic LH secretion.Wethus
conclude that the KNDy neuropeptides act in the arcuate nucleus to control episodic GnRH secretion
in the ewe, but afferent input from GnRH neurons to this area does not. These data support
the proposed roles forNKBand dynorphin within theKNDyneural network and raise the possibility
that kisspeptin contributes to the control ofGnRHpulse frequency in addition to its established role
as an output signal from KNDy neurons that drives GnRH pulses.National Institutes of Health
Grants R01-HD039916 and RO1-HD017864.http://press.endocrine.org/journal/endoam201
Automated Regional Modelling (ARM) for characterization of the substorm current wedge
Poster, ICS-9, Seggau, Austria, May 2008Some characteristics of substorms may be determined through use of an electrojet forward modelling approach. These include the amplitude of cross-meridian electric current (0.2 to 1 MA typically), timescales (about 20 minutes to peak current and poleward extension), and amount of poleward motion (several degrees). An increase in the number of magnetic stations deployed in North America makes use of a full substorm current wedge system possible, reproducing well the perturbations observed both in the auroral zone and at subauroral stations. This provides good characterization not only of the aforementioned parameters, but also of the substorm longitudinal parameters including the central meridian. In principle, extension of near-Earth field-aligned currents into space is possible based on inversion results and field models. In practice, comparison with data from spacecraft such as THEMIS is complicated by processes in space such as plasma sheet changes at substorm onse
Attitudes toward Precision Treatment of Smoking in the Southern Community Cohort Study
Background: Precision interventions using biological data may enhance smoking treatment, yet are understudied among smokers who are disproportionately burdened by smoking-related disease. Methods: We surveyed smokers in the NCI-sponsored Southern Community Cohort Study, consisting primarily of African-American, low-income adults. Seven items assessed attitudes toward aspects of precision smoking treatment, from undergoing tests to acting on results. Items were dichotomized as favorable (5 = strongly agree/4 = agree) versus less favorable (1 = strongly disagree/2 = disagree/3 = neutral); a summary score reflecting generalized attitudes was also computed. Multivariable logistic regression tested independent associations of motivation (precontemplation, contemplation, and preparation) and confidence in quitting (low, medium, and high) with generalized attitudes, controlling for sociodemographic factors and nicotine dependence. Results: More than 70% of respondents endorsed favorable generalized attitudes toward precision medicine, with individual item favorability ranging from 64% to 83%. Smokers holding favorable generalized attitudes reported higher income and education (P \u3c 0.05). Predicted probabilities of favorable generalized attitudes ranged from 63% to 75% across motivation levels [contemplation vs. precontemplation: adjusted odds ratio (AOR) = 2.10, 95% confidence interval (CI), 1.36–3.25, P = 0.001; preparation vs. precontemplation: AOR = 1.83, 95% CI, 1.20–2.78, P = 0.005; contemplation vs. preparation: AOR = 1.15, 95% CI, 0.75–1.77, P = 0.52] and from 59% to 78% across confidence (medium vs. low: AOR = 1.91, 95% CI, 1.19–3.07, P = 0.007; high vs. low: AOR = 2.62, 95% CI, 1.68–4.10, P \u3c 0.001; medium vs. high: AOR = 0.73, 95% CI, 0.48–1.11, P = 0.14). Conclusions: Among disproportionately burdened community smokers, most hold favorable attitudes toward precision smoking treatment. Individuals with lower motivation and confidence to quit may benefit from additional intervention to engage with precision smoking treatment. Impact: Predominantly favorable attitudes toward precision smoking treatment suggest promise for future research testing their effectiveness and implementation
Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin's Lymphoma
Brentuximab vedotin is an anti-CD30 antibody-drug conjugate that has been approved for relapsed and refractory Hodgkin's lymphoma
Trading between healthy food, alcohol and physical activity behaviours
BACKGROUND: While recent lifestyle studies have explored the role that food, alcohol or physical activity have on health and wellbeing, few have explored the interplay between these behaviours and the impact this has on a healthy lifestyle. Given the long term health advantages associated with leading healthier lifestyles, this study seeks to: 1) explore the interplay between the food, alcohol and physical activity behaviours of young adults (aged 19–26 years) in the North East of England; 2) explore the trade-offs young adults make between their food, alcohol and physical activity behaviours; and 3) recognise the positive and negative associations between the three behaviours. METHODS: Qualitative self-reported lifestyle diaries and in-depth interviews were conducted with 50 young adults from the North East of England between February and June 2008. Qualitative thematic analysis was undertaken using Nvivo QSR software, and diary coding using Windiets software. RESULTS: Young adults who attempt to achieve a ‘healthy lifestyle’ make trade-offs between the food and alcohol they consume, and the amounts of physical activity they undertake. There are negative reasons and positive consequences associated with these trade-offs. Young adults recognise the consequences of their behaviours and as a result are prepared to undertake healthy behaviours to compensate for unhealthy behaviours. They prefer certain strategies to promote healthier behaviours over others, in particular those that relate to personalised advice and support, more affordable ways to be healthier and easily-accessed advice from a range of media sources. CONCLUSIONS: Young adults seek to compensate unhealthy behaviours (e.g. binge drinking) with healthy behaviours (e.g. physical activity). Creative solutions may be required to tackle these trade-offs and promote a balance across the food, alcohol and physical activity behaviours of this age group. Solutions that may be effective with this age group include environmental changes (e.g. green spaces and increasing the price of alcohol) designed to encourage and facilitate young people making healthier choices and improving their access to, and lowering the price of, healthy food products. Solutions must recognise these trade-offs and in particular, the strong reluctance of young adults to alter their higher-than-recommended levels of alcohol consumption
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