10 research outputs found
Evidence of habitat fragmentation affecting fish movement between the Patos and Mirim coastal lagoons in southern Brazil
Diet and feeding strategy of the dusky grouper Mycteroperca marginata (Actinopterygii: Epinephelidae) in a man-made rocky habitat in southern Brazil
Attention-deficit/hyperactivity disorder drugs and growth: an Italian prospective observational study.
Feeding ecology of two sympatric species of large-sized groupers (Perciformes: Epinephelidae) on Southwestern Atlantic coralline reefs
Reproductive biology of the dusky grouper (Epinephelus marginatus) at the southern limit of its distribution in the south-western Atlantic
A review of the biology, ecology, behavior and conservation status of the dusky grouper, Epinephelus marginatus (Lowe 1834)
Attention-deficit/hyperactivity disorder drugs and growth: an Italian prospective observational study.
Attention-deficit/hyperactivity disorder drugs and growth: an Italian prospective observational study.
OBJECTIVE:
This study was conducted to assess the long-term effect of methylphenidate (MPH) or atomoxetine (ATX) on growth in attention-deficit/hyperactivity disorder (ADHD) drug-naïve children.
DESIGN:
The study was an observational, post-marketing, fourth phase study.
METHODS:
Data on height and weight were collected at baseline and every 6 months up to 24 months.
RESULTS:
Both ATX and MPH lead to decreased height gain (assessed by means of z-scores); the effect was significantly higher for ATX than for MPH. At any time, height z-score decrease in the ATX group was higher than the corresponding decrease observed in the MPH group, but the difference was significantly relevant only during the first year of treatment. An increment of average weight was observed both in patients treated with MPH and in those treated with ATX. However, using Tanner's percentile, a subset of patients showed a degree of growth lower than expected. This negative effect was significantly higher for ATX than for MPH.
CONCLUSIONS:
We conclude that ADHD drugs show a negative effect on linear growth in children in middle term. Such effect appears more evident for ATX than for MPH