Tunable dipolar magnetism in high-spin molecular clusters

We report on the Fe17 high-spin molecular cluster and show that this system is an exemplification of nanostructured dipolar magnetism. Each Fe17 molecule, with spin S=35/2 and axial anisotropy as small as D=-0.02K, is the magnetic unit that can be chemically arranged in different packing crystals whilst preserving both spin ground-state and anisotropy. For every configuration, molecular spins are correlated only by dipolar interactions. The ensuing interplay between dipolar energy and anisotropy gives rise to macroscopic behaviors ranging from superparamagnetism to long-range magnetic order at temperatures below 1K.Comment: Replaced with version accepted for publication in Physical Review Letter

Evaluating the Pennebaker Paradigm with Bereaved Emerging Adults: Applications of Text Analysis

Bereavement is an important research area as it can result in grief reactions that lead to serious psychological and health consequences, particularly for the at-risk group of emerging adults (Arnett, 2000; Balk, Walker, & Baker, 2010; Fisher, Murray, & Frazer, 1985; Stroebe, Schut, & Stroebe, 2007). Expressive writing is a well-researched intervention for trauma and adjustment, yet research repeatedly has revealed null results with the classic Pennebaker paradigm as a bereavement intervention (Stroebe et al., 2002; Stroebe, Schut, & Stroebe, 2006). It may be premature, however, to conclude expressive writing is ineffective for the bereaved due to limitations in extant research. For example, Pennebaker’s paradigm is based on the premise that participants freely choose the stressful topic to write about, whereas expressive writing bereavement studies have required participants to write about their loss (Collison & Gramling, manuscript in preparation). The present study reports on data from a larger study (Konig, Eonta, Dyal, & Vrana, 2014; N=246) that assessed psychological and physiological outcomes in college students who wrote about a traumatic stressor using Pennebaker’s paradigm. This provided the opportunity to rigorously test it with bereavement and compare death loss to other forms of trauma. Analyses examined the impact of expressive writing with the bereaved who freely identified death loss as the traumatic stressor (n=69) and were randomly assigned to either emotional disclosure or control writing on outcome measures of physical symptoms (PILL), event-related distress (DTS), and depression (CES-D). Linguistic Inquiry and Word Count (LIWC; Pennebaker, Mayne, & Francis, 1997) and Latent Semantic Analysis (LSA; Campbell & Pennebaker, 2003) results were also used to compare these groups. Exploratory analyses investigated potential differences between the bereaved and those who endorsed a non-bereavement trauma (“other trauma”; n=71) using outcome measures and text analytic techniques (i.e., PILL, DTS, CES-D; LIWC, LSA). Results were consistent with findings from previous expressive writing studies with the bereaved, in that the intervention resulted in no detectable benefits when compared with control writing. No remarkable differences between the bereaved and “other trauma” participants emerged. Researchers’ time may be better spent examining more clinically relevant writing exercises for bereavement interventions

Legal determinants of external finance revisited : the inverse relationship between investor protection and societal well-being

This paper investigates relationships between corporate governance traditions and quality of life as measured by a number of widely reported indicators. It provides an empirical analysis of indicators of societal health in developed economies using a classification based on legal traditions. Arguably the most widely cited work in the corporate governance literature has been the collection of papers by La Porta et al. which has shown, inter alia, statistically significant relationships between legal traditions and various proxies for investor protection. We show statistically significant relationships between legal traditions and various proxies for societal health. Our comparative evidence suggests that the interests of investors may not be congruent with the interests of wider society, and that the criteria for judging the effectiveness of approaches to corporate governance should not be restricted to financial metrics

Associations of body mass index, physical activity and sedentary time with blood pressure in primary school children from south-west England: a prospective study

Elevated blood pressure in children is a significant risk factor for the development of cardiovascular disease in adulthood. We examined how children's body mass index (BMI), physical activity and sedentary time at ages 9 and 11 are associated with blood pressure at age 11. Data were from 1283 children from Bristol, UK, who participated in the study aged 11 years, 797 of whom also participated in the study aged 9 years. Child height, weight and blood pressure were measured, and children wore accelerometers for five days, from which moderate-to-vigorous-intensity physical activity and sedentary minutes per day were derived. Multiple imputation of missing data and adjusted linear and logistic regression models were used to examine associations. Child BMI at 11 years was cross-sectionally associated with higher systolic and diastolic blood pressure (mean difference [95% confidence interval]: 0.91 [0.32 to 1.50] mm Hg and 1.08 [0.54 to 1.62] mm Hg, respectively, per standard deviation (SD) of BMI). BMI at age 9 was also positively associated with diastolic blood pressure at age 11 (1.16 mmHg per two years [0.49 to 1.84], per SD of BMI). For girls, sedentary time at age 9 years was associated with increased odds of having high systolic blood pressure at age 11 (odds ratio: 1.08 [1.01 to 1.16], per 10 minutes per day). There was no evidence of associations between sedentary time and blood pressure among boys. Similarly, there was little evidence that physical activity was associated with blood pressure in either cross-sectional or prospective analyses. Effective strategies are needed to prevent excess bodyweight among children in order to reduce cardiovascular disease risk

Modelling Conformational Flexibility in a Spectrally Addressable Molecular Multi-Qubit Model System

Dipolar coupled multi-spin systems have the potential to be used as molecular qubits. Herein we report the synthesis of a molecular multi-qubit model system with three individually addressable, weakly interacting, spin (Formula presented.) centres of differing g-values. We use pulsed Electron Paramagnetic Resonance (EPR) techniques to characterise and separately address the individual electron spin qubits; CuII, Cr7Ni ring and a nitroxide, to determine the strength of the inter-qubit dipolar interaction. Orientation selective Relaxation-Induced Dipolar Modulation Enhancement (os-RIDME) detecting across the CuII spectrum revealed a strongly correlated CuII-Cr7Ni ring relationship; detecting on the nitroxide resonance measured both the nitroxide and CuII or nitroxide and Cr7Ni ring correlations, with switchability of the interaction based on differing relaxation dynamics, indicating a handle for implementing EPR-based quantum information processing (QIP) algorithms

Polarimetry of Li-rich giants

Protoplanetary nebulae typically present non-spherical envelopes. The origin of such geometry is still controversial. There are indications that it may be carried over from an earlier phase of stellar evolution, such as the AGB phase. But how early in the star's evolution does the non-spherical envelope appear? Li-rich giants show dusty circumstellar envelopes that can help answer that question. We study a sample of fourteen Li-rich giants using optical polarimetry in order to detect non-spherical envelopes around them. We used the IAGPOL imaging polarimeter to obtain optical linear polarization measurements in V band. Foreground polarization was estimated using the field stars in each CCD frame. After foreground polarization was removed, seven objects presented low intrinsic polarization (0.19 - 0.34)% and two (V859 Aql and GCSS 557) showed high intrinsic polarization values (0.87 - 1.16)%. This intrinsic polarization suggests that Li-rich giants present a non-spherical distribution of circumstellar dust. The intrinsic polarization level is probably related to the viewing angle of the envelope, with higher levels indicating objects viewed closer to edge-on. The correlation of the observed polarization with optical color excess gives additional support to the circumstellar origin of the intrinsic polarization in Li-rich giants. The intrinsic polarization correlates even better with the IRAS 25 microns far infrared emission. Analysis of spectral energy distributions for the sample show dust temperatures for the envelopes tend to be between 190 and 260 K. We suggest that dust scattering is indeed responsible for the optical intrinsic polarization in Li-rich giants. Our findings indicate that non-spherical envelopes may appear as early as the red giant phase of stellar evolution.Comment: to be published in A&A, 15 pages, 10 figures. Fig. 3 is available in ftp://astroweb.iag.usp.br/pub/antonio/4270/4270.fig3.pd

Critical Error Frequency and the Impact of Training with Inhalers Commonly used for Maintenance Treatment in Chronic Obstructive Pulmonary Disease

Introduction: Training in correct inhaler use, ideally in person or by video demonstration, can minimize errors but is rarely provided in clinics. This open-label, low-intervention study evaluated critical error rates with dry-powder inhalers (DPIs), before and after training, in patients with chronic obstructive pulmonary disease. Methods: Patients prescribed an inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA) (ELLIPTA, Turbuhaler, or DISKUS), long-acting muscarinic antagonist (LAMA)/LABA (ELLIPTA or Breezhaler), or LAMA-only DPI (ELLIPTA, HandiHaler, or Breezhaler) were enrolled. Critical errors were assessed before training (Visit 1 [V1]; primary endpoint) and 6 weeks thereafter (Visit 2 [V2]; secondary endpoint). Logistic regression models were used to calculate odds ratios (ORs) for between-group comparisons. Results: The intent-to-treat population comprised 450 patients. At V1, fewer patients made ≥ 1 critical error with ELLIPTA (10%) versus other ICS/LABA DPIs (Turbuhaler: 40%, OR 4.66, P=0.005; DISKUS: 26%, OR 2.48, P=0.114) and other LAMA or LAMA/LABA DPIs (HandiHaler: 34%, OR 3.50, P=0.026; Breezhaler: 33%, OR 3.94, P=0.012). Critical error rates with the primary ICS/LABA DPI were not significantly different between ELLIPTA ICS/LABA (10%) and ICS/LABA plus LAMA groups (12– 25%). Critical errors with the primary ICS/LABA DPI occurred less frequently with ELLIPTA ICS/LABA with or without LAMA (11%) versus Turbuhaler ICS/LABA with or without LAMA (39%, OR 3.99, P< 0.001) and DISKUS ICS/LABA with or without LAMA (26%, OR 2.18, P=0.069). Simulating single-inhaler versus multiple-inhaler triple therapy, critical error rates were lower with ELLIPTA fluticasone furoate/vilanterol (FF/VI; 10%) versus ELLIPTA FF/VI plus LAMA (22%), considering errors with either DPI (OR 2.50, P=0.108). At V2, critical error rates decreased for all DPIs/groups, reaching zero only for ELLIPTA. Between-group comparisons were similar to V1. Conclusion: Fewer patients made critical errors with ELLIPTA versus other ICS/LABA, and LAMA or LAMA/LABA DPIs. The effect of “verbal” training highlights its importance for reducing critical errors with common DPIs