Cost effectiveness of community leg ulcer clinics: randomised controlled trial

Objectives: To establish the relative cost effectiveness of community leg ulcer clinics that use four layer compression bandaging versus usual care provided by district nurses. Design: Randomised controlled trial with 1 year of follow up. Setting: Eight community based research clinics in four trusts in Trent. Subjects: 233 patients with venous leg ulcers allocated at random to intervention (120) or control (113) group. Interventions: Weekly treatment with four layer bandaging in a leg ulcer clinic (clinic group) or usual care at home by the district nursing service (control group). Main outcome measures: Time to complete ulcer healing, patient health status, and recurrence of ulcers. Satisfaction with care, use of services, and personal costs were also monitored. Results: The ulcers of patients in the clinic group tended to heal sooner than those in the control group over the whole 12 month follow up (log rank P=0.03). At 12 weeks, 34% of patients in the clinic group were healed compared with 24% in the control. The crude initial healing rate of ulcers in intervention compared with control patients was 1.45 (95% confidence interval 1.04 to 2.03). No significant differences were found between the groups in health status. Mean total NHS costs were £878.06 per year for the clinic group and £859.34 for the control (P=0.89). Conclusions: Community based leg ulcer clinics with trained nurses using four layer bandaging is more effective than traditional home based treatment. This benefit is achieved at a small additional cost and could be delivered at reduced cost if certain service configurations were used

Huge automatically extracted training sets for multilingual Word Sense Disambiguation

We release to the community six large-scale sense-annotated datasets in multiple language to pave the way for supervised multilingual Word Sense Disambiguation. Our datasets cover all the nouns in the English WordNet and their translations in other languages for a total of millions of sense-tagged sentences. Experiments prove that these corpora can be effectively used as training sets for supervised WSD systems, surpassing the state of the art for low- resourced languages and providing competitive results for English, where manually annotated training sets are accessible. The data is available at trainomatic. org

Providing Internet access to Los Alamos National Laboratory technical reports: A case history in providing public access to previously restricted documents

The Los Alamos National Laboratory (LANL) Research Library recently fulfilled a strategic goal of providing worldwide desktop access via the Internet to full-image files of the complete unclassified holdings of Los Alamos technical reports in its Report Collection. This effort began in late 1994 with the scanning of paper and microfiche format reports. Concurrently, the Research Library helped to initiate shifting the model for publishing new technical reports from paper to electronic; the files could then be directly mounted on the Research Library`s Web server. Providing desktop access to these reports was instrumental in expediting the development of internal policies that would better define what documents, previously restricted to the general public, could be publicly released. Undoubtedly, the most significant category of such reports were previously classified reports that had been declassified, but had not gone through a further review for public release. Collaboration with LANL`s Classification Group led to approval for public release of 97% of these reports. The LANL Research Library`s Web site now offers unique and unprecedented access to the world of a huge body of technical reports never available before anywhere in any form. This paper discusses the issues and steps involved in this achievement

Single-spin Azimuthal Asymmetries in the ``Reduced Twist-3 Approximation''

We consider the single-spin azimuthal asymmetries recently measured at the HERMES experiment for charged pions produced in semi-inclusive deep inelastic scattering of leptons off longitudinally polarized protons. Guided by the experimental results and assuming a vanishing twist-2 transverse quark spin distribution in the longitudinally polarized nucleon, denoted as ``reduced twist-3 approximation'', a self-consistent description of the observed single-spin asymmetries is obtained. In addition, predictions are given for the z dependence of the single target-spin asymmetry.Comment: 8 pages, 2 figures, typos corrected, very small changes to text, reference adde

Novel Transversity Properties in Semi-Inclusive Deep Inelastic Scattering

The $T$-odd distribution functions contributing to transversity properties of the nucleon and their role in fueling nontrivial contributions to azimuthal asymmetries in semi-inclusive deep inelastic scattering are investigated. We use a dynamical model to evaluate these quantities in terms of HERMES kinematics.Comment: 5 pages revtex; 5 eps figures. References added. To appear as a Rapid Communication in Physical Review

A genetic-based algorithm for personalized resistance training

Association studies have identified dozens of genetic variants linked to training responses and sport-related traits. However, no intervention studies utilizing the idea of personalised training based on athlete’s genetic profile have been conducted. Here we propose an algorithm that allows achieving greater results in response to high- or low-intensity resistance training programs by predicting athlete’s potential for the development of power and endurance qualities with the panel of 15 performance-associated gene polymorphisms. To develop and validate such an algorithm we performed two studies in independent cohorts of male athletes (study 1: athletes from different sports (n=28); study 2: soccer players (n=39)). In both studies athletes completed an eight-week high- or low-intensity resistance training program, which either matched or mismatched their individual genotype. Two variables of explosive power and aerobic fitness, as measured by the countermovement jump (CMJ) and aerobic 3-min cycle test (Aero3) were assessed pre and post 8 weeks of resistance training. In study 1, the athletes from the matched groups (i.e. high-intensity trained with power genotype or low-intensity trained with endurance genotype) significantly increased results in CMJ (P=0.0005) and Aero3 (P=0.0004). Whereas, athletes from the mismatched group (i.e. high-intensity trained with endurance genotype or lowintensity trained with power genotype) demonstrated non-significant improvements in CMJ (P=0.175) and less prominent results in Aero3 (P=0.0134). In study 2, soccer players from the matched group also demonstrated significantly greater (P<0.0001) performance changes in both tests compared to the mismatched group. Among non- or low responders of both studies, 82% of athletes (both for CMJ and Aero3) were from the mismatched group (P<0.0001). Our results indicate that matching the individual’s genotype with the appropriate training modality leads to more effective resistance training. The developed algorithm may be used to guide individualised resistance-training interventions

Perturbative contribution to the sin(phi) asymmetry in inclusive pi^{+} electroproduction

We consider the sin(phi) single target-spin asymmetry in deep-inelastic pi^{+} inclusive electroproduction off a longitudinally polarized target. We show that at larger transverse momentum of the outgoing hadron the evaluated asymmetry decreases if one takes into account the first order alpha_S perturbative contribution to the cross section, integrated over the azimuthal angle. This leads to good agreement with recent HERMES data.Comment: 4 pages with one figure, LaTeX, typos corrected. Contribution to the Proceedings of the QCD'00 Euroconference, Montpellier, 6-13th July 2000, to appear in the Nucl. Phys. B (Proc. Suppl.

Left-right asymmetry for pion and kaon production in the semi-inclusive deep inelastic scattering process

We analyze the left-right asymmetry in the semi-inclusive deep inelastic scattering (SIDIS) process without introducing any weighting functions. With the current theoretical understanding, we find that the Sivers effect plays a key role in our analysis. We use the latest parametrization of the Sivers and fragmentation functions to reanalyze the $\pi^\pm$ production process and find that the results are sensitive to the parametrization. We also extend our calculation on the $K^{\pm}$ production, which can help us know more about the Sivers distribution of the sea quarks and the unfavored fragmentation processes. HERMES kinematics with a proton target, COMPASS kinematics with a proton, deuteron, and neutron target (the information on the neutron target can be effectively extracted from the $^3$He target), and JLab kinematics (both 6 GeV and 12 GeV) with a proton and neutron target are considered in our paper.Comment: 7 latex pages, 11 figures, final version for publication, with references update