Expectation in Auditory Processing of Environmental Sounds in People with Fluent Aphasia

The purpose of this study was to examine the integrity of the nonverbal auditory system in subjects with fluent aphasia, and determine the relative preservation of the nonverbal auditory system in comparison to the lexical system. This was attempted through the task of expectation, a high level processing skill. Two groups of participants were examined: a group with fluent aphasia, and a group of non-neurologically damaged individuals. Participants were administered two nonverbal auditory conditions devoid of lexical information, a simple condition and a complex condition in which they were required to determine if the last sound heard in a sequence of four was expected or unexpected. Two lexical conditions were also administered in a similar manner. In the simple lexical condition, participants were required to identify if the last word heard in a sequence of four was expected or unexpected. In the complex lexical condition, participants were instructed to identify if a sentence ended in a logical or illogical word. The measures in this study included reaction times, percent correct, and incongruent percent correct for each condition. Results revealed that subjects with aphasia may have deficits in auditory processing of both nonverbal and lexical information. A significant difference was found in that subjects with aphasia performed better on lexical tasks as compared to nonverbal auditory tasks. Subjects with aphasia appeared to have a damaged nonverbal auditory system; however, it is inconclusive as to if these results were exacerbated by the complexity of the nonverbal stimuli or the manner in which these complex stimuli were presented devoid of visual and situational context

Tussles with ambidexterity: The case of managers of health professional education

This case study explores the lived experience of managers within an academic faculty concerned with the professional education of the health care workforce in the UK. Recent advances in the global trend towards the marketisation of Higher Education and the current era of public and quasi-public-sector austerity, sees these actors tasked with practising their craft amidst a powerful set of forces which are transforming their world of work and raising opportunities and challenges in equal measure. At the heart of these challenges lies the imperative to maintain and enhance current capabilities whilst simultaneously adopting a future orientation to develop new ones. The extant literature offers powerful evidence of the efficacy of the construct of ambidexterity as a lens through which to understand the way in which organisations and individuals pursue these dual aims and provides a fitting theoretical framework for the study. The case study integrates data elicited from interviews with managers with archival documentary data, relating to a four-year period, to facilitate analysis on both an individual and business-unit level. The findings offer a novel exploration of the construct of ambidexterity in the Higher Education arena and address the plethora of calls to advance our understanding regarding managers’ interpretation and responses to the tensions which arise from the pursuit of ambidexterity. The research makes a unique contribution to the existing body of knowledge revealing a conceptualisation of contextual ambidexterity in which the dual modes of operation (exploitation and exploration) are positioned along a continuum. Context-specific ambidextrous tensions emerge, including the dichotomous perception of other educational providers as both competitors and collaborators and the enduring deleterious impact of explorative activity on exploitative endeavours. Ambidextrous tactics are also in evidence with the imperative to develop social capital with external stakeholders, who are espoused with consumer sovereignty, taking precedence in this complex educational marketplace. Together the findings afford a unique insight into the way that managers of professional healthcare education perceive and manage the complexity and dynamism of ambidexterity in their everyday practice

Synthesis and Study of Olefin Metathesis Catalysts Supported by Redox-Switchable Diaminocarbene 3 Ferrocenophanes

A redox-switchable ligand, N,N'-dimethyldiaminocarbene[3]ferrocenophane (5), was synthesized and incorporated into a series of Ir- and Ru-based complexes. Electrochemical and spectroscopic analyses of (5) Ir(CO)(2)Cl (15) revealed that 5 displayed a Tolman electronic parameter value of 2050 cm(-1) in the neutral state and 2061 cm(-1) upon oxidation. Moreover, inspection of X-ray crystallography data recorded for (5) Ir(cis,cis-1,5-cyclooctadiene)Cl (13) revealed that 5 was sterically less bulky (%V-Bur = 28.4) than other known diaminocarbene[3]ferrocenophanes, which facilitated the synthesis of (5)(PPh3)Cl2Ru-(3-phenylindenylid-1-ene) (18). Complex 18 exhibited quasi-reversible electrochemical processes at 0.79 and 0.98 V relative to SCE, which were assigned to the Fe and Ru centers in the complex, respectively, based on UV-vis and electron pair resonance spectroscopic measurements. Adding 2,3-dichloro-5,6-dicyanoquinone over the course of a ring-opening metathesis polymerization of cis, cis-1,5-cyclooctadiene catalyzed by 18 ([monomer](0)/[18](0) = 2500) reduced the corresponding rate constant of the reaction by over an order of magnitude (pre-oxidation: k(obs) = 0.045 s(-1); post-oxidation: k(obs) = 0.0012 s(-1)). Subsequent reduction of the oxidized species using decamethylferrocene restored catalytic activity (post-reduction: k(obs) = up to 0.016 s(-1), depending on when the reductant was added). The difference in the polymerization rates was attributed to the relative donating ability of the redox-active ligand (i.e., strongly donating 5 versus weakly donating 5(+)) which ultimately governed the activity displayed by the corresponding catalyst.U. S. Army Research Office W911NF-09-1-0446Chemistr

Aspects of the relationship between part-time maternal employment, infant socio-emotional development in the second year of life, and maternal satisfaction

In 2 volsAvailable from British Library Document Supply Centre-DSC:DX206879 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Meta-Learning for Color-to-Infrared Cross-Modal Style Transfer

Recent object detection models for infrared (IR) imagery are based upon deep neural networks (DNNs) and require large amounts of labeled training imagery. However, publicly-available datasets that can be used for such training are limited in their size and diversity. To address this problem, we explore cross-modal style transfer (CMST) to leverage large and diverse color imagery datasets so that they can be used to train DNN-based IR image based object detectors. We evaluate six contemporary stylization methods on four publicly-available IR datasets - the first comparison of its kind - and find that CMST is highly effective for DNN-based detectors. Surprisingly, we find that existing data-driven methods are outperformed by a simple grayscale stylization (an average of the color channels). Our analysis reveals that existing data-driven methods are either too simplistic or introduce significant artifacts into the imagery. To overcome these limitations, we propose meta-learning style transfer (MLST), which learns a stylization by composing and tuning well-behaved analytic functions. We find that MLST leads to more complex stylizations without introducing significant image artifacts and achieves the best overall detector performance on our benchmark datasets

Integration of biological effects, fish histopathology and contaminant measurements for the assessment of fish health: A pilot application in Irish marine waters

This study investigates the use of a weight of evidence (WOE) approach to evaluate fish health status and biological effects (BEs) of contaminants for assessment of ecosystem health and discusses its potential application in support of the Marine Strategy Framework Directive (MSFD). External fish disease, liver histopathology and several BEs of contaminant exposure including 7-ethoxy resorufin O-de-ethylase (EROD), acetylcholinesterase (AChE), bile metabolites, vitellogenin (VTG) and alkali labile phosphates (ALP) were measured in two flatfish species from four locations in Ireland. Contaminant levels in fish were generally low with PCBs in fish liver below OSPAR environmental assessment criteria (EAC). There were consistencies with low PCB levels, EROD and PAH bile metabolite levels detected in fish. Dab from Cork, Dublin and Shannon had the highest relative prevalence of liver lesions associated with the carcinogenic pathway. An integrated biomarker response (IBR) showed promise to be useful for evaluation of environmental risk, although more contaminant parameters in liver are required for a full assessment with the present study

From Aaron to Ivanhoe

A collection of Bulloch County history materials compiled by Charles Bonds, Dorothy Brannen, Maggie Collins, Dan Good, Nkenge Jackson, Evelyn Mabry, Carolyn Postell, Robert M. Seel, and Rita Turner Wall. Included are a brief history of Bulloch County, an article on local 19th century architecture, two accounts on county history by Rita Turner Wall, a short history of Willow Hill School, a report on the research on Willow Hill School, “Extinct Towns in Bulloch County,” “Pretoria Station,” the biographies of Beatrice Riggs and Laura Bell Hendley Martin, three articles from the Bulloch Times on the memories of a Confederate veteran and the 1865 Census of Bulloch County. The index to this collection was compiled by Julius Ariail.https://digitalcommons.georgiasouthern.edu/bchs-pubs/1014/thumbnail.jp

Evaluation of Non-destructive Molecular Diagnostics for the Detection of Neoparamoeba perurans

Peer reviewed paper. Citation: Downes, J. K., Rigby, M. L., Taylor, R. S., Maynard, B. T., MacCarthy, E., O’Connor, I., Marcos-Lopez M., Rodger H. D., Collins E., Ruane N. M. & Cook, M. T. (2017). Evaluation of Non-destructive Molecular Diagnostics for the Detection of Neoparamoeba perurans. Frontiers in Marine Science, 4. https://doi.org/10.3389/fmars.2017.00061 Link: https://www.frontiersin.org/articles/10.3389/fmars.2017.00061/full DOI: https://doi.org/10.3389/fmars.2017.00061 Cited as per the open access policy of Frontiers Media SA.Amoebic gill disease (AGD) caused by Neoparamoeba perurans, has emerged in Europe as a significant problem for the Atlantic salmon farming industry. Gross gill score is the most widely used and practical method for determining AGD severity on farms and informing management decisions on disease mitigation strategies. As molecular diagnosis of AGD remains a high priority for much of the international salmon farming industry, there is a need to evaluate the suitability of currently available molecular assays in conjunction with the most appropriate non-destructive sampling methodology. The aims of this study were to assess a non-destructive sampling methodology (gill swabs) and to compare a range of currently available real-time polymerase chain-reaction (PCR) assays for the detection of N. perurans. Furthermore a comparison of the non-destructive molecular diagnostics with traditional screening methods of gill scoring and histopathology was also undertaken. The study found that all molecular protocols assessed performed well in cases of clinical AGD with high gill scores. A TaqMan based assay (protocol 1) was the optimal assay based on a range of parameters including % positive samples from a field trial performed on fish with gill scores ranging from 0 to 5. A higher proportion of gill swab samples tested positive by all protocols than gill filament biopsies and there was a strong correlation between gill swabs tested by protocol 1 and gross gill score and histology scores. Screening for N. perurans using protocol 1 in conjunction with non-destructive gill swab samples was shown to give the best results