An Exploration of Community Palliative Care Clinical Nurse Specialists Experiences of Working as Independent Prescribers: Part 2

The Department of Health has recently reiterated its commitment to the improvement in the quality of end of life care and emphasized the importance of all patients having rapid access to medication. The aim of this study was to explore the lived experiences of clinical nurse specialists who are able to prescribe independently in their role in providing support for patients with palliative care needs within the community setting. Interpretive phenomenology was employed in order to understand and interpret the experiences of six nurse independent prescribes employed as community palliative care clinical nurse specialists. This purposive sampling was preferred with semi-structured interviews as the most appropriate data collection technique. Participants interviewed reported that being able to prescribe enabled them to provide seamless, holistic care which facilitated faster access to medicines for their patients. This was particularly apparent at weekends when the patient's usual general practitioner (GP) was unavailable. Several benefits of nurse independent prescribing were also highlighted. However, the main barrier identified by most participants was the difficulty in accessing the patient's records. The overwhelming conclusion was that independent prescribing by community nurse specialists is beneficial for patients in the palliative care phase of their life and those deemed important to them as they are being cared for at home. Such benefits can also impact on other aspects of the patient's life including prompt availability of medicines, effective symptom control and consequently, an improved or enhanced quality of life for the patients and job satisfaction for the prescribing specialists nurses

Joint Cosmological Formation of QSOs and Bulge-dominated Galaxies

Older and more recent pieces of observational evidence suggest a strong connection between QSOs and galaxies; in particular, the recently discovered correlation between black hole and galactic bulge masses suggests that QSO activity is directly connected to the formation of galactic bulges. The cosmological problem of QSO formation is analyzed in the framework of an analytical model for galaxy formation; for the first time a joint comparison with galaxy and QSO observables is performed. In this model it is assumed that the same physical variable which determines galaxy morphology is able to modulate the mass of the black hole responsible for QSO activity. Both halo spin and the occurence of a major merger are considered as candidates to this role. The predictions of the model are compared to available data for the type-dependent galaxy mass functions, the star-formation history of elliptical galaxies, the QSO luminosity function and its evolution (including the obscured objects contributing to the hard-X-ray background), the mass function of dormant black holes and the distribution of black-hole -- bulge mass ratios. A good agreement with observations is obtained if the halo spin modulates the efficiency of black-hole formation, and if the galactic halos at $z=0$ have shone in an inverted order with respect to the hierarchical one (i.e., stars and black holes in bigger galactic halos have formed before those in smaller ones). This inversion of hierarchical order for galaxy formation, which reconciles galaxy formation with QSO evolution, is consistent with many pieces of observational evidence.Comment: 20 pages, figures included, mn.sty, in press on MNRAS, fig 6 changed (new data added at z=4.4

Study of B0 -> rho+-pi-+ Time-dependent CP Violation at Belle

We present a time-dependent analysis of CP violation in B0 -> rho pi decays based on a 140 1/fb data sample collected at the Y(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. We fully reconstruct one neutral B meson in the rho+-pi-+ final state and identify the flavor of the accompanying B meson from its decay products. We obtain the charge asymmetry ACP = -0.16+-0.10(stat)+-0.02(syst). An unbinned maximum likelihood fit to the proper-time distributions yields C = 0.25+-0.17(stat)+0.02-0.06(syst), DC = 0.38+-0.18(stat)+0.02-0.04(syst), S = -0.28+-0.23(stat)+0.10-0.08(syst), and DS = -0.30+-0.24(stat)+-0.09(syst). The direct CP violation parameters for B -> rho+pi- and B -> rho-pi+ decays are A+- = -0.02+-0.16(stat)+0.05-0.02(syst) and A-+ = -0.53+-0.29(stat)+0.09-0.04(syst).Comment: 10 pages, 3 figures, submitted to Phys. Rev. Let

Study of CP Violating Effects in Time Dependent B0(B0ˉ)→D(∗)∓π±B^0(\bar{B^0}) \to D^{(*)\mp}\pi^{\pm} Decays

We report measurements of time dependent decay rates for $B^0(\bar{B}^0) \to D^{(*)\mp}\pi^{\pm}$ decays and extraction of CP violation parameters containing $\phi_3$. Using fully reconstructed $D^{(*)}\pi$ events from a $140 {\rm fb}^{-1}$ data sample collected at the $\Upsilon(4S)$ resonance, we obtain the CP violation parameters for $D^* \pi$ and $D \pi$ decays, $2R_{D^{(*)} \pi} \sin (2\phi_1 + \phi_3 \pm \delta_{D^{(*)} \pi})$, where $R_{D^{(*)} \pi}$ is the ratio of the magnitudes of the doubly-Cabibbo-suppressed and Cabibbo-favoured amplitudes, and $\delta_{D^{(*)} \pi}$ is the strong phase difference between them. Under the assumption of $\delta_{D^{(*)} \pi}$ being close to either 0 or $180^{\circ}$, we obtain $|2R_{D^* \pi} \sin (2\phi_1 + \phi_3)| = 0.060 \pm 0.040(\mathrm{stat}) \pm 0.019(\mathrm{sys})$ and $|2R_{D \pi} \sin (2\phi_1 + \phi_3)| = 0.061 \pm 0.037(\mathrm{stat}) \pm 0.018(\mathrm{sys})$.Comment: 9 pages, 3 figures, Submitted to Physical Review Letter

Measurement of the B --> K^* gamma Branching Fractions and Asymmetries

We report measurements of the radiative decay B --> K^*\gamma. The analysis is based on a data sample containing 85.0*10^6 B meson pairs collected by the Belle detector at the KEKB storage ring. We measure branching fractions of Br(B^0 --> K^{*0}\gamma) = (4.01 \pm 0.21 \pm 0.17)*10^{-5} and Br(B^+ --> K^{*+}\gamma) = (4.25 \pm 0.31 \pm 0.24)*10^{-5}, where the first and second errors are statistical and systematic, respectively. The isospin asymmetry between B^0 and B^+ decay widths is measured to be \Delta_{0+} = +0.012 \pm 0.044 \pm 0.026. We search for a partial rate asymmetry between CP conjugate modes, and find A_{cp}(B --> K^*\gamma) = =0.015 \pm 0.044 \pm 0.012.Comment: 10 pages, 5 figures, submitted to Phys. Rev.

Search for lepton-flavor violation at HERA

A search for lepton-flavor-violating interactions $e p \to \mu X$ and $e p\to \tau X$ has been performed with the ZEUS detector using the entire HERA I data sample, corresponding to an integrated luminosity of 130 pb^{-1}. The data were taken at center-of-mass energies, $\sqrt{s}$, of 300 and 318 GeV. No evidence of lepton-flavor violation was found, and constraints were derived on leptoquarks (LQs) that could mediate such interactions. For LQ masses below $\sqrt{s}$, limits were set on $\lambda_{eq_1} \sqrt{\beta_{\ell q}}$, where $\lambda_{eq_1}$ is the coupling of the LQ to an electron and a first-generation quark $q_1$, and $\beta_{\ell q}$ is the branching ratio of the LQ to the final-state lepton $\ell$ ($\mu$ or $\tau$) and a quark $q$. For LQ masses much larger than $\sqrt{s}$, limits were set on the four-fermion interaction term $\lambda_{e q_\alpha} \lambda_{\ell q_\beta} / M_{\mathrm{LQ}}^2$ for LQs that couple to an electron and a quark $q_\alpha$ and to a lepton $\ell$ and a quark $q_\beta$, where $\alpha$ and $\beta$ are quark generation indices. Some of the limits are also applicable to lepton-flavor-violating processes mediated by squarks in $R$-Parity-violating supersymmetric models. In some cases, especially when a higher-generation quark is involved and for the process $e p\to \tau X$, the ZEUS limits are the most stringent to date.Comment: 37 pages, 10 figures, Accepted by EPJC. References and 1 figure (Fig. 6) adde

Inclusive jet cross sections and dijet correlations in D∗±D^{*\pm} photoproduction at HERA

Inclusive jet cross sections in photoproduction for events containing a $D^*$ meson have been measured with the ZEUS detector at HERA using an integrated luminosity of $78.6 {\rm pb}^{-1}$. The events were required to have a virtuality of the incoming photon, $Q^2$, of less than 1 GeV$^2$, and a photon-proton centre-of-mass energy in the range $130<W_{\gamma p}<280 {\rm GeV}$. The measurements are compared with next-to-leading-order (NLO) QCD calculations. Good agreement is found with the NLO calculations over most of the measured kinematic region. Requiring a second jet in the event allowed a more detailed comparison with QCD calculations. The measured dijet cross sections are also compared to Monte Carlo (MC) models which incorporate leading-order matrix elements followed by parton showers and hadronisation. The NLO QCD predictions are in general agreement with the data although differences have been isolated to regions where contributions from higher orders are expected to be significant. The MC models give a better description than the NLO predictions of the shape of the measured cross sections.Comment: 43 pages, 12 figures, charm jets ZEU

Measurement of event shapes in deep inelastic scattering at HERA

Inclusive event-shape variables have been measured in the current region of the Breit frame for neutral current deep inelastic ep scattering using an integrated luminosity of 45.0 pb^-1 collected with the ZEUS detector at HERA. The variables studied included thrust, jet broadening and invariant jet mass. The kinematic range covered was 10 < Q^2 < 20,480 GeV^2 and 6.10^-4 < x < 0.6, where Q^2 is the virtuality of the exchanged boson and x is the Bjorken variable. The Q dependence of the shape variables has been used in conjunction with NLO perturbative calculations and the Dokshitzer-Webber non-perturbative corrections (`power corrections') to investigate the validity of this approach.Comment: 7+25 pages, 6 figure

Observation of Large CP Violation and Evidence for Direct CP Violation in B0-->pi+pi- Decays

We report the first observation of CP-violating asymmetries in B0 --> pi+pi- decays based on a 140 fb-1 data sample collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. We reconstruct one neutral B meson as a B0 --> pi+pi- CP eigenstate and identify the flavor of the accompanying B meson from its decay products. We apply an unbinned maximum likelihood fit to the distribution of the time intervals between the two B meson decay points. The fit yields the CP-violating asymmetry amplitudes Apipi = +0.58+/-0.15(stat)+/-0.07(syst) and Spipi = -1.00+/-0.21(stat)+/-0.07(syst). We rule out the CP-conserving case, Apipi=Spipi=0, at a level of 5.2 standard deviations. We also find evidence for direct CP violation with a significance at or greater than 3.2 standard deviations for any Spipi value.Comment: 9 pages, 3 figure

Beauty photoproduction measured using decays into muons in dijet events in ep collisions at s\sqrt{s}=318 GeV

The photoproduction of beauty quarks in events with two jets and a muon has been measured with the ZEUS detector at HERA using an integrated luminosity of 110 pb$^{- 1}$. The fraction of jets containing b quarks was extracted from the transverse momentum distribution of the muon relative to the closest jet. Differential cross sections for beauty production as a function of the transverse momentum and pseudorapidity of the muon, of the associated jet and of $x_{\gamma}^{jets}$, the fraction of the photon's momentum participating in the hard process, are compared with MC models and QCD predictions made at next-to-leading order. The latter give a good description of the data.Comment: 32 pages, 6 tables, 7 figures Table 6 and Figure 7 revised September 200