Estimation of spleen volume and surface area of the newborns’ cadaveric spleen using stereological methods

Background: The purpose of this study was to compare different techniques for the estimation of spleen volume and surface area using magnetic resonance imaging (MRI) images, ultrasonography (USG) images and cadaveric specimen, and to evaluate errors associated with volume estimation techniques based onfluid displacement.Materials and methods: Five new born cadavers, aged 39.7 ± 1.5 weeks, weighted 2.220 ± 1.056 g, were included in the present study. Three different methods were used to assess the spleen volume. The vertical section technique was applied using cycloid test probes for estimation of spleen surface area in MRI.Results: The mean ± standard deviation of spleen volumes by fluid displacement was 4.82 ± 3.85 cm3. Volumes determined by the Cavalieri’s principle using physical section and point-counting techniques were 4.45 ± 3.47 cm3 and 4.65 ± 3.75 cm3, respectively; volumes measured by USG and cadaver using ellipsoid formula were 4.70 ± 3.02 cm3 and 5.98 ± 4.58 cm3, respectively. No significant differences were found among all methods (p > 0.05). The spleen surface area was calculated as a 32.3 ± 20.6 cm2 by physical sections using cadaver and also it was determined on axial, sagittal and coronal MR planes as 24.9 ± 15.2 cm2, 18.5 ± 5.92 cm2 and 24.3 ± 12.7 cm2, respectively.Conclusions: As a result, MR images allow an easy, reliable and reproducible volume and surface area estimation of normal and abnormal spleen using Cavalieri’sprinciple. We consider that our study may serve as a reference for similar studies to be conducted in future

PARADOXICAL REACTIONS, ESPECIALLY PSORIASIS IN RHEUMATOLOGY PATIENTS RECEIVING BIOLOGIC THERAPY FROM THE TREASURE DATABASE: A 5-YEAR FOLLOW-UP STUDY

EULAR European Congress of Rheumatology (EULAR) -- JUN 01-04, 2022 -- Copenhagen, DENMARK[Abstract Not Available]European Alliance Assoc Rheumato

Exact Solutions of the Duffin Kemmer Petiau Equation for the Deformed Hulthen Potential

Using the Nikiforov Uvarov method, an application of the relativistic Duffin Kemmer Petiau equation in the presence of a deformed Hulthen potential is presented for spin zero particles. We derived the first order coupled differential radial equations which enable the energy eigenvalues as well as the full wavefunctions to be evaluated by using of the Nikiforov Uvarov method that can be written in terms of the hypergeometric polynomials.Comment: 8 pages. submitted to Physica Script

EPIDEMIOLOGICAL CHARACTERISTICS OF VIRAL HEPATITIS IN PATIENTS WITH RHEUMATIC DISEASES - IMPLICATIONS FROM TREASURE DATABASE

EULAR European Congress of Rheumatology (EULAR) -- JUN 01-04, 2022 -- Copenhagen, DENMARK[Abstract Not Available]European Alliance Assoc Rheumato

Influencia de un injerto en el perfil de ácidos grasos y algunas propiedades fisicoquímicas de la semilla y el aceite de semillas de sandía

This study aimed to investigate the effects of grafting on the fatty acid profile and some physicochemical properties of watermelon seed and seed oil. The ‘Crimson Tide’ cultivar was used as the scion while two wild watermelon (Citrullus lanatus var. citroides (A1 and A2)), one Lagenaria siceraria (A3) and one Cucurbita maxima Duchesne x Cucurbita moschata Duchesne (A4) were used as rootstocks. The use of rootstock significantly influenced the fatty acid profile and the physical parameters of seeds and seed oils. The highest linoleic acid ratio was found in the seed oil from A1 and A2, the oil from A3 had the highest oleic acid ratio. The results showed that the content and acid value in seed oils were improved, and that total phenolic compounds and antioxidant activity of both seed and oil were decreased by grafting. Wild rootstocks can be used in watermelon cultivation to obtain a watermelon seed which is rich in linoleic acid.El objetivo de este estudio fue investigar los efectos del injerto en el perfil de ácidos grasos y algunas propiedades fisicoquímicas de la semilla y el aceite de semillas de sandía. El cultivar ‘Crimson Tide’ se utilizó como vástago, mientras que dos sandías silvestres (Citrullus lanatus var. Citroides (A1 y A2)), una Lagenaria siceraria (A3) y una Cucurbita maxima Duchesne x Cucurbita moschata Duchesne (A4) se utilizaron como portainjertos. El uso de portainjertos influyó significativamente en el perfil de ácidos grasos y los parámetros físicos de semillas y aceites de semillas. La proporción de ácido linoleico más alta se encontró en el aceite de semillas de A1 y A2, el aceite de A3 tuvo la proporción de ácido oleico más alta. Los resultados mostraron que el contenido de aceite y el índice de acidez mejoró y los compuestos fenólicos totales y la actividad antioxidante tanto de la semilla como del aceite se redujeron mediante el injerto. Para obtener un aceite de semillas de sandía rico en ácido linoleico, se pueden utilizar portainjertos silvestres en el cultivo de sandía

Dose-dependent effect of Scolymus hispanicus L. (sevketibostan) on ethylene glycol-induced kidney stone disease in rats

7-13Kidney stone, also known as calcium oxalate nephrolithiasis, is one of the most common diseases worldwide. Calculi usually forms when urine becomes supersaturated with particular calcium salts such as calcium oxalate. In the present study, we investigated the ameliorative potential of the root extract of the Common golden thistle, Scolymus hispanicus L. (SH) on rats with ethylene glycol (EG) induced kidney stone disease. Sprague-Dawley rats, each weighing 250-300 g, were divided into three groups (n=6 per group): (i) Control (C); (ii) EG; and (iii) EG+SH. To induce nephrolithiasis, the rats received 1% of EG with drinking water, while the C group received normal drinking water during the study. SH extract 2 g/kg was added to the treatment from the 4th week onwards in EG+SH group. At the end of each experiment, rats were decapacitated and serum levels of calcium, magnesium, phosphorus, creatinine, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) were assessed in all groups at 0, 4, and 8 weeks. Oxalic acid and creatininelevels were measured in urine samples collected at 24 h in metabolic cages. Renal tissues were evaluated histopathologically at the end of the experiment. After 8 weeks, serum creatinine levels were found decreased in the SH group while increased in the EG group. Serum magnesium and AST levels were also found decreased in the EG group, however, SH treatment reversed these values. The SH treatment also increased urinary oxalic acid levels. When the kidney tissue of EG group was examined, there was a high level of crystal/stone, especially in the renal cortex. In kidney tissues of the SH group, only small amounts of crystal/stone were observed. Our experimental findings have demonstrated the ameliorative potential of the aqueous extracts of S. hispanicus roots and shells on EG-induced in the kidney stones in rats. Isolation of active compounds of SH would be desirable to understand the biochemical mechanism behind the process better

Morphological evaluation and clinical significance of the supracondylar process and supratrochlear foramen: an anatomic and radiological study

Background: In our literature review, we did not encounter any study examining the supracondylar process (SP) and the supratrochlear foramen (STF) with a three-dimensional (3D) reconstruction method. The present study aimed to evaluate SP and STF morphologically by employing the 3D reconstruction method and emphasize their clinical significance. Materials and methods: The research was carried out on dried human humeri of unknown sex and without pathological alterations. A total of 81 humeri (42 right, 39 left) were obtained from the Departments of Anatomy of Gazi University Faculty of Medicine and Lokman Hekim University Faculty of Medicine. The morphometric measurements of SP and STF were made with a digital vernier caliper. The computed tomography (CT) images acquired for radiological evaluation were analyzed with the 3D reconstruction method. Results: The narrower distal medullary canal widths of humeri with STF were found to be statistically significant. No statistically significant difference was found between the transverse diameters (TD), vertical diameters (VD), the distance of the medial edge to the medial epicondyle (ME), and the distance of the lateral edge to the lateral epicondyle (LE) of the supratrochlear foramen of the right and left humeri. Conclusions: The supracondylar process is often evaluated by mistake as a pathological condition of the bone, not as a normal anatomical variation. Knowing different shapes and dimensions, e.g., the TD and VD distance in which STF emerges, can assist in avoiding the misinterpretation of radiographs

Transmutations and spectral parameter power series in eigenvalue problems

We give an overview of recent developments in Sturm-Liouville theory concerning operators of transmutation (transformation) and spectral parameter power series (SPPS). The possibility to write down the dispersion (characteristic) equations corresponding to a variety of spectral problems related to Sturm-Liouville equations in an analytic form is an attractive feature of the SPPS method. It is based on a computation of certain systems of recursive integrals. Considered as families of functions these systems are complete in the $L_{2}$-space and result to be the images of the nonnegative integer powers of the independent variable under the action of a corresponding transmutation operator. This recently revealed property of the Delsarte transmutations opens the way to apply the transmutation operator even when its integral kernel is unknown and gives the possibility to obtain further interesting properties concerning the Darboux transformed Schr\"{o}dinger operators. We introduce the systems of recursive integrals and the SPPS approach, explain some of its applications to spectral problems with numerical illustrations, give the definition and basic properties of transmutation operators, introduce a parametrized family of transmutation operators, study their mapping properties and construct the transmutation operators for Darboux transformed Schr\"{o}dinger operators.Comment: 30 pages, 4 figures. arXiv admin note: text overlap with arXiv:1111.444