12 research outputs found

    Evaluation of Excessive Daytime Sleepiness with Sleep Apnea and Determining the Relationship Between Life Quality

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    Aim:Obstructive Sleep Apnea syndrome (OSAS) is an important health issue characterized by repetitive episodes of upper airway obstruction affecting many different systems in the human body. In this study, we aimed to examine the relationship of daytime sleepiness with quality of life in patients with OSAS.Methods:In this study, adult patients, who underwent diagnostic polysomnography for the first time in our clinic, were included. Data on physical examination findings and demographic characteristics were recorded. The Epworth Sleepiness Scale, 36-Item Short Form Health Survey (SF-36), Beck Anxiety Inventory, and the Beck Depression Inventory were administered to the patients.Results:A total of 136 patients with the mean age of 45.5±9.7 (22- 68) were included in the study. Thirty four patients were (25%) female and 102 were male (75%). Simple snoring was detected in 30 patients (22.1%), mild OSAS in 24 patients (17.6%), moderate OSAS in 26 patients (19.1%) and severe OSAS was found in 56 patients (42.1%). Epworth Sleepiness Scale scores in patients with severe OSAS were statistically significantly higher than in other patients. The lowest SF-36 scores were observed in severe OSAS patients.Conclusion:The quality of life was significantly decreased in patients with severe OSAS. We assume that quality life was negatively correlated Epworth Sleepiness Scale scores

    Deep Neck Infections: A Retrospective Analysis of Eighty Five Cases

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    Aim: In our study, we assessed symptoms and treatment outcomes in patients with deep neck infections (DNI). It often has a rapid onset and can cause lethal complications. Methods: A retrospective designed study of 85 patients diagnosed with DNI such as peritonsillar, parapharyngeal, and submandibular abscesses. Results: A total of 85 patients were diagnosed with DNI. 33 of the 85 patients were younger than 18 (group of children), and 52 were older than 18 years of age (group of adults). The mean age of the patients was 24.109±14.003 (4-54) years. Trismus, fever, odynophagia and pain were the most common complaints in both groups. In the adults group, the peritonsillar space was the most common site of infection (49%). In children group, the parapharyngeal space was the most common site of infection (35%). All patients were given intravenous antibiotic therapy and additional drainage of the abscess was also carried out for some of the patients. Most frequently, intravenous ampicillin-sulbactam alone or in combination with metronidazole was administrated to the patients. Conclusion: Most of the cases of DNI can be treated with intravenous antibiotics in spite of the fact that if there is no clinical healing, drainage is needed

    Results of Thyroglossal Duct Cysts and Fistulas Surgery in Our Clinic

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    Aim: In this study, we aimed to discuss the examination findings, clinical features and treatment methods in 72 patients, who were operated for thyroglossal duct cyst, in the light of the relevant literature. Methods: We retrospectively analyzed the medical reports of 72 patients who were operated due to thyroglossal duct cyst in our clinic. Results: Forty-eight patients were male and 24 were female. The age at presentation ranged from 10 to 56 years (average age: 16.8±15.7 years). The most common complaint was fistula point at the middle region of the neck (58%). Rarely, a nodule or intermittent secretion was being at the middle of the neck in patients. Fistula point or nodule was settled at the midline of the neck and thyrohyoid zone in 16 patients. Clinic presentation was a fistula in 38 patients and a cyst in 34 patients. Sistrunk operation was performed in all patients. Conclusion: Thyroglossal duct cyst should be considered in the differential diagnosis of patients presenting with neck swelling and discharge from the midline. Thyroglossal duct cysts should be treated surgically due to the risk of malignant transformation. Sistrunk surgery, with its low recurrence rate and low risk of complications, is the gold standard in the treatment of thyroglossal duct cysts

    Comparative investigation of protective effects of metyrosine and metoprolol against ketamine cardiotoxicity in rats

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    Ahiskalioglu, Ali/0000-0002-8467-8171; ALP, Hamit Hakan/0000-0002-9202-4944; Ahiskalioglu, Ali/0000-0002-8467-8171; AKSOY, Mehmet/0000-0003-0867-8660WOS: 000361605900005PubMed: 25503950This study investigated the effect of metyrosine against ketamine-induced cardiotoxicity in rats and compared the results with the effect of metoprolol. in this study, rats were divided into groups A, B and C. in group A, we investigated the effects of a single dose of metyrosine (150 mg/kg) and metoprolol (20 mg/kg) on single dose ketamine (60 mg/kg)-induced cardiotoxicity. in group B, we investigated the effect of metyrosine and metoprolol, which were given together with ketamine for 30 days. in group C, we investigated the effect of metyrosine and metoprolol given 15 days before ketamine and 30 days together with ketamine on ketamine cardiotoxicity. By the end of this process, we evaluated the effects of the levels of oxidant-antioxidant parameters such as MDA, MPO, 8-OHGua, tGSH, and SOD in addition to CK-MB and TP I on cardiotoxicity in rat heart tissue. the experimental results show that metyrosine prevented ketamine cardiotoxicity in groups A, B and C and metoprolol prevented it in only group C
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