2017 Economic Impact of Companies Funded and/or Assisted by the Northeast Ohio Entrepreneurial Service Provider Program

The 2018 report on the economic impact of companies funded and/or assisted by the Northeast Ohio Entrepreneurial Services Provider Program (ESP) shows findings and evidence of the growth of the supported firms over time. These companies not only have a significant workforce and expenditures, they also have a total of 2,313 issued patents and 6,777 patents pending. In 2017 alone, there were 891 issued patents and 920 patents pending. The ESP is a collaborative entrepreneurial support network funded in part by Ohio Third Frontier that includes accelerators, incubators, angel funds, and other organizations dedicated to commercializing technologies and fostering promising entrepreneurial ventures in Northeast Ohio. The companies included in this report have received significant technical assistance and/or direct investment funding from entrepreneurial support organizations in the ESP. The report measures the economic impact of early-stage companies that were supported in the past by JumpStart Inc. and its partners in the Northeast Ohio ESP in 2017

2017 Economic Impact of Companies Funded and/or Assisted by the Northeast Ohio Entrepreneurial Service Provider Program

The 2018 report on the economic impact of companies funded and/or assisted by the Northeast Ohio Entrepreneurial Services Provider Program (ESP) shows findings and evidence of the growth of the supported firms over time. These companies not only have a significant workforce and expenditures, they also have a total of 2,313 issued patents and 6,777 patents pending. In 2017 alone, there were 891 issued patents and 920 patents pending. The ESP is a collaborative entrepreneurial support network funded in part by Ohio Third Frontier that includes accelerators, incubators, angel funds, and other organizations dedicated to commercializing technologies and fostering promising entrepreneurial ventures in Northeast Ohio. The companies included in this report have received significant technical assistance and/or direct investment funding from entrepreneurial support organizations in the ESP. The report measures the economic impact of early-stage companies that were supported in the past by JumpStart Inc. and its partners in the Northeast Ohio ESP in 2017

Parallel Deterministic Neutron Transport with AMR

AMTRAN, a one, two and three dimensional Sn neutron transport code with adaptive mesh refinement (AMR) has been parallelized with MPI over spatial domains and energy groups and with threads over angles. Block refined AMR is used with linear finite element representations for the fluxes, which are node centered. AMR requirements are determined by minimum mean free path calculations throughout the problem and can provide an order of magnitude or more reduction in zoning requirements for the same level of accuracy, compared to a uniformly zoned problem

Pond Culture of Walleye Fingerlings

Walleye, Stitzostedion vitreum, has potential to be an aquaculture species in the North Central Region because: it is native to the region; it maintains optimum growth at temperatures lower than many other current aquaculture species (such as channel catfish); it is a highly-prized sport fish; its flesh is considered a delicacy; and the fillets are high in protein and . low in fat, making walleye an attractive food selection for today’s health conscious consumer

Automatic Calibration of an Airborne Imaging System to an Inertial Navigation Unit

This software automatically calibrates a camera or an imaging array to an inertial navigation system (INS) that is rigidly mounted to the array or imager. In effect, it recovers the coordinate frame transformation between the reference frame of the imager and the reference frame of the INS. This innovation can automatically derive the camera-to-INS alignment using image data only. The assumption is that the camera fixates on an area while the aircraft flies on orbit. The system then, fully automatically, solves for the camera orientation in the INS frame. No manual intervention or ground tie point data is required

Real-Time Feature Tracking Using Homography

This software finds feature point correspondences in sequences of images. It is designed for feature matching in aerial imagery. Feature matching is a fundamental step in a number of important image processing operations: calibrating the cameras in a camera array, stabilizing images in aerial movies, geo-registration of images, and generating high-fidelity surface maps from aerial movies. The method uses a Shi-Tomasi corner detector and normalized cross-correlation. This process is likely to result in the production of some mismatches. The feature set is cleaned up using the assumption that there is a large planar patch visible in both images. At high altitude, this assumption is often reasonable. A mathematical transformation, called an homography, is developed that allows us to predict the position in image 2 of any point on the plane in image 1. Any feature pair that is inconsistent with the homography is thrown out. The output of the process is a set of feature pairs, and the homography. The algorithms in this innovation are well known, but the new implementation improves the process in several ways. It runs in real-time at 2 Hz on 64-megapixel imagery. The new Shi-Tomasi corner detector tries to produce the requested number of features by automatically adjusting the minimum distance between found features. The homography-finding code now uses an implementation of the RANSAC algorithm that adjusts the number of iterations automatically to achieve a pre-set probability of missing a set of inliers. The new interface allows the caller to pass in a set of predetermined points in one of the images. This allows the ability to track the same set of points through multiple frames

Sequential Transphosphorylation of the BRI1/BAK1 Receptor Kinase Complex Impacts Early Events in Brassinosteroid Signaling

SummaryBrassinosteroids (BRs) regulate plant development through a signal transduction pathway involving the BRI1 and BAK1 transmembrane receptor kinases. The detailed molecular mechanisms of phosphorylation, kinase activation, and oligomerization of the BRI1/BAK1 complex in response to BRs are uncertain. We demonstrate that BR-dependent activation of BRI1 precedes association with BAK1 in planta, and that BRI1 positively regulates BAK1 phosphorylation levels in vivo. BRI1 transphosphorylates BAK1 in vitro on specific kinase-domain residues critical for BAK1 function. BAK1 also transphosphorylates BRI1, thereby quantitatively increasing BRI1 kinase activity toward a specific substrate. We propose a sequential transphosphorylation model in which BRI1 controls signaling specificity by direct BR binding followed by substrate phosphorylation. The coreceptor BAK1 is then activated by BRI1-dependent transphosphorylation and subsequently enhances signaling output through reciprocal BRI1 transphosphorylation. This model suggests both conservation and distinct differences between the molecular mechanisms regulating phosphorylation-dependent kinase activation in plant and animal receptor kinases

An Old Lineage of Cyphophthalmi (Opiliones) Discovered on Mindanao Highlights the Need for Biogeographical Research in the Philippines

The arachnid order Opiliones, and the suborder Cyphophthalmi in particular, have recently been used to test biogeographical patterns in Southeast Asia due to their ancient age and extremely low vagility. Here we report the first Cyphophthalmi—two juveniles—known from Mindanao in the southern Philippine Archipelago, and we place them in a molecular phylogeny to test biogeographical hypotheses for their colonization of that island. Five molecular markers were sequenced from one specimen, three from the other, and these sequences were added to a previously completed phylogenetic analysis. The specimens were recovered as members of a clade found almost exclusively on Borneo. Their deep placement within this clade suggests a very old origin and colonization that perhaps involved the mysterious landmass now underlying Mindanao's Zamboanga Peninsula. This species prompts new questions about the abilities of Southeast Asian Cyphophthalmi (Stylocellidae) to disperse and colonize, and it emphasizes how much remains to be understood about the geological history of the Philippines.Organismic and Evolutionary Biolog

Breaking out of biogeographical modules: range expansion and taxon cycles in the hyperdiverse ant genus Pheidole

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