6 research outputs found

    Clues in the diagnosis and management of acute glaucoma for general practitioners and emergency physicians

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    Para los m茅dicos de urgencias es un verdadero problema el paciente con patolog铆a oftalmol贸gica, porque son ellos los primeros que se enfrentan el diagn贸stico y manejo inicial de estos pacientes. No es desconocido que el glaucoma (ataque agudo de glaucoma) es una patolog铆a de consulta frecuente en los servicios de urgencias, por lo que su diagn贸stico, as铆 como su adecuado manejo, debe ser r谩pido y acertado para evitar secuelas irreversibles. Este art铆culo busca facilitar las herramientas para el diagn贸stico y el adecuado manejo del paciente que presenta un ataque agudo de glaucoma.Art铆culo de revisi贸n536-542For general practitioners it is a great problem to deal with ophthalmic pathology; however they are the first doctors that face the diagnosis, and management of those patients. They are the first to take care of the initial management of the patient presenting with angle closure glaucoma. This diagnosis and management must be right and proper to avoid irreversible sequelae. This article gives special clues and tips for an early diagnosis and quick management of angle closure glaucoma, to prevent blindness from this pathology

    Pautas para el examen oftalmol贸gico. Enfoque para el estudiante de medicina y el m茅dico general

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    El examen oftalmol贸gico debe ser una actividad obligatoria para el estudiante de medicina y el m茅dico general. Su realizaci贸n es de suma importancia en la atenci贸n de pacientes con s铆ntomas oculares, quienes requieren una evaluaci贸n oftalmol贸gica completa y una descripci贸n cl铆nica adecuada. Este art铆culo surge ante la necesidad que tienen los estudiantes de medicina y los m茅dicos generales de realizar un adecuado examen oftalmol贸gico en sus pr谩cticas cl铆nicas, con el fin de poder establecer diagn贸sticos claros y as铆 brindar un tratamiento correcto o solicitar la remisi贸n pertinente a un paciente que requiera el cuidado de un oftalm贸logo

    Pautas para el examen oftalmol贸gico. Enfoque para el estudiante de medicina y el m茅dico general

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    El examen oftalmol贸gico debe ser una actividad obligatoria para el estudiante de medicina y el m茅dico general. Su realizaci贸n es de suma importancia en la atenci贸n de pacientes con s铆ntomas oculares, quienes requieren una evaluaci贸n oftalmol贸gica completa y una descripci贸n cl铆nica adecuada. Este art铆culo surge ante la necesidad que tienen los estudiantes de medicina y los m茅dicos generales de realizar un adecuado examen oftalmol贸gico en sus pr谩cticas cl铆nicas, con el fin de poder establecer diagn贸sticos claros y as铆 brindar un tratamiento correcto o solicitar la remisi贸n pertinente a un paciente que requiera el cuidado de un oftalm贸logo

    Early detection of optic nerve head changes using optical coherence tomography after using mesenchymal stromal cells as intravitreal therapy in rabbit models of ocular hypertension

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    Background and Aim: Stem cell therapy is considered a promising treatment for several neurodegenerative diseases. However, there are very few studies on the use of this therapy in glaucoma models. By detecting the changes produced by glaucoma early, cell therapy could help prevent the events that lead to blindness. In this study, early changes in the optic nerve head (ONH) as detected by optical coherence tomography (OCT) after the application of human Wharton鈥檚 jelly-derived mesenchymal stromal cells (hWJ-MSCs) in an experimental model of ocular hypertension (OH) were evaluated. Materials and Methods: Fifteen New Zealand rabbits were randomly divided into the following three groups: G1: OH, G2: hWJ-MSCs, and G3: OH + hWJ-MSCs. An OH model was constructed, and the intraocular pressure (IOP) was measured regularly. At week 7, 105/100 渭L hWJ-MSCs were intravitreally injected. Retinography and OCT were used to evaluate structural changes in ONH. Results: IOP increased significantly in G1 and G3 from week 3 onward. Retinography revealed more significant optic nerve changes, that is, papillary asymmetry suggestive of optic nerve excavation, vascular alterations, and irregular hypopigmentation peripheral to the optic disk margin, in G1 compared with G3. OH locates the hWJ-MSCs solution in the vitreous in front of the optic nerve. OCT revealed retinal nerve fiber layer (RNFL) reduction in all groups, reduced optic cup volume in G2 and G3 between weeks 1 and 9, and significant ganglion cell layer thickness reduction in G1 and a slight increase in G3. Conclusion: Intravitreal hWJ-MSCs injection produced changes in optic cup volume, which were detected early on by OCT; however, RNFL could not be restored in this OH model
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