Evolving library services in the ever-​changing world of chemical information: From printed to electronic to networked

Access to chem. information has evolved dramatically over the past 50 years, from printed to electronic to networked. Channeling and focusing this torrent of information to meet the specific needs of researchers has increased exponentially over time, and has required librarians to become beta testers, instructors, and negotiators. Dana Roth's contributions to chem. information, and to the field of librarianship as a whole, cannot be overestimated. This talk will highlight key contributions that Roth has made to the relationships between the Caltech Library and publishers, and between the Library and the campus research community. These relationships continue to flourish and expand, and examples of past efforts and current projects from across the Caltech Library will be discussed

The Grizzly, April 7, 1992

Mr. Resident Assistant, Chris Foust, Wins Mr. Ursinus Title • First Phi Beta Kappa Members Inducted • Today\u27s Health • New College House • Health Service Changes Set for Next Year • Congratulations to the Newly Elected USGA and Class Officers! • Lindback Award Nominations • Key Senior Donations • Roving Reporter: Should Marijuana be Legalized? • The Academy Awards and High Hollywood Fashion • Berman Exhibits Students\u27 Work • New Carnivore Kingdom to Open at the Zoo • Olin Cellist • A Measurable Success • Celebrity Spotlight • D.C. Art Internship • USGA Minutes • Environmental Notes • Talk Shows: TV\u27s Big Lie • Campus Memo • Special Olympics Hosted • Golf Goes 4-0https://digitalcommons.ursinus.edu/grizzlynews/1990/thumbnail.jp

The Grizzly, April 28, 1992

Earth Day 1992: Fun for All • CoreStates Grants Grant • UC History Majors Present Papers • U.C. a hit at U.N. • Holocaust Survivor Speaks • Scholarly Hat Trick in Biology • Political Cartoonist To Speak • Strunk Runs for Office • Spring Weekend Great Success • Concert Band & Jazz Ensemble Perform • Exam Schedule • Student Art Exhibition Opens, Awards Presented • Wismer\u27s Modern Art Spy • First Friends First • Sophomore Chats Tell All • Letter: Strunk Thanks Democrats • Men\u27s Lacrosse Splits Weekendhttps://digitalcommons.ursinus.edu/grizzlynews/1296/thumbnail.jp

Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis

To identify maternal clinical risk factors for postcesarean maternal infection in a randomized clinical trial of preincision extended-spectrum antibiotic prophylaxis

The Grizzly, February 18, 1992

Fraternity Pledging in Full Swing • Commencement Speaker Chosen • Today\u27s Health • Energy-Savers • Tau Sig Clothing Drive • Jolly Green Giants • Frederick Douglass Now • A Capella Entertainment • Movie Review: Thelma and Louise • Japan Bashing: Justified or Not? • Laff-a-Lympics • Letters: Can I Graduate?; Pepe\u27s Problem • Hoopsters Continue to Get Dunked • Hoop-A-Holics Come out on Top • Lady Bears Break Team Record • Aquabears End Season with a Splashhttps://digitalcommons.ursinus.edu/grizzlynews/1290/thumbnail.jp

The Grizzly, February 11, 1992

Lorene Cary Speaks on Diversity in America • The XVI Winter Olympics Begin in Albertville • Healthy Dieting • Berman Exhibit • Volkmer Wins Contest • A New Beat for an Old Measure • A Guide to That Perfect Night Out • We Have a Winner • Sculpture Update • Movie Review: City Slickers • Corson Creatures • CAB Comedian Shocks and Thrills Crowd • 5th Avenue a Cappella Coming Soon • Take Good Care of My Baby • Leadership • Letter: Term Limitations - A Change in the System • Wrestling Takes Down Competition • Swimmers Make Waves • Men\u27s Basketball Bounces by Johns Hopkins • Lady Bears Dribble to Victoryhttps://digitalcommons.ursinus.edu/grizzlynews/1289/thumbnail.jp

The Grizzly, March 24, 1992

Sororities Honored for Participation in Blood Drive • Economist Speaks on Recession • Sailing on the Chesapeake • U.S.G.A. Minutes • Consider Women\u27s Studies Next Semester • Senior Class: Please Give • Fraternity Pledging Ends • Admitted Students Reception • Precipitation Indication • Maquette Exhibit • Movie Review: Hot Shots • New Sculpture Exhibit to Open • Movie Review: My Cousin Vinny • CAB Performers Humor and Hypnotize • Touchstone Ensemble\u27s Interpretation of Candide • Stop Complaining; Start Conserving • Letters: More Responses to Airband Controversy • (Sic)\u27em: A Concern Over Grizzly Policy • Men and Women Swimmers End Season • Derstine, Cauley at Nationals • Freshman Power and the Liberty Bell • Gymnasts Finish Seasonhttps://digitalcommons.ursinus.edu/grizzlynews/1293/thumbnail.jp

The Grizzly, February 25, 1992

Airband 1992 Raises Over $1,200 for Charity • Flasher Hits Collegeville • Exchange Student to Speak • Good News For Bio Majors • Democratic Candidates • A Century of Main Street • Granite Column and Marble Bench • Wayne and Garth Big Hit in Wayne\u27s World • Jazz Quintet & Clifford Jordan to Perform • Movie Review: Dying Young • Americans Need to Lighten Up • Participation in Class: Intimidating or Not? • Men\u27s Basketball Stumbles to an End • Gymnasts Excel • Winter Olympics Comes to a Close • Lady Bears Win PAIAW Championship • Wrestlers Finish Strong Seasonhttps://digitalcommons.ursinus.edu/grizzlynews/1291/thumbnail.jp

Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression.

Platelets have a wide range of functions including critical roles in hemostasis, thrombosis, and immunity. We hypothesized that during acute inflammation, such as in life-threatening sepsis, there are fundamental changes in the sites of platelet production and phenotypes of resultant platelets. Here, we showed during sepsis that the spleen was a major site of megakaryopoiesis and platelet production. Sepsis provoked an adrenergic-dependent mobilization of megakaryocyte-erythrocyte progenitors (MEPs) from the bone marrow to the spleen, where IL-3 induced their differentiation into megakaryocytes (MKs). In the spleen, immune-skewed MKs produced a CD40 ligandhi platelet population with potent immunomodulatory functions. Transfusions of post-sepsis platelets enriched from splenic production enhanced immune responses and reduced overall mortality in sepsis-challenged animals. These findings identify a spleen-derived protective platelet population that may be broadly immunomodulatory in acute inflammatory states such as sepsis.NHS Blood and Transplant European Union's Horizon 2020 (ERC-2014-CoG-648765) MRC-AMED (MR/V005421/1