Hire Education: Mastery, Modularization and the Workforce Revolution

This new research identifies online competency-based learning as the solution to shifting demands for specialized workforce skills and the front runner for disrupting higher education

Deprofessionalization, Proletarianization, and Social Welfare Work

In this paper we explore the personnel transformations which have occurred in social welfare work. Specifically, we examine the tensions between the dynamics of professionalization and deprofessionalization and how these trends have impacted upon those who work in the social welfare enterprise. Another concern of the paper is the effect of the proletarianization of social welfare work in the face of increasing efforts of some to create professional standards and to solidify the position of professionals in agencies. These struggles are examined in terms of their ability to affect the likelihood of both worker unionization and worker-client political coalitions

Exchange Rules in the Mediation of Social Welfare Work

This article demonstrates the utility of the concept of exchange rules for understanding welfare worker agency in the mediation of workplace ideologies and behaviors. The exchange rules of complementarity, reciprocity, and beneficence are applied to the issues of service worker burnout, worker-client interactions, and labor issues to illustrate their conceptual and practical power. This analysis from an interactionist perspective complements the macro-level observations of the fundamental contradictions within the social welfare enterprise. It also suggests avenues for the mediation and alleviation of certain workplace dilemmas

Pragmatic randomized controlled trial of providing access to a brief personalized alcohol feedback intervention in university students

BACKGROUND There is a growing body of evidence indicating that web-based personalized feedback interventions can reduce the amount of alcohol consumed in problem drinking college students. This study sought to evaluate whether providing voluntary access to such an intervention would have an impact on drinking. METHODS College students responded to an email inviting them to participate in a short drinking survey. Those meeting criteria for risky drinking (and agreeing to participate in a follow-up) were randomized to an intervention condition where they were offered to participate in a web-based personalized feedback intervention or to a control condition (intervention not offered). Participants were followed-up at six weeks. RESULTS A total of 425 participants were randomized to condition and 68% (n = 290) completed the six-week follow-up. No significant difference in drinking between conditions was observed. CONCLUSIONS Web-based personalized feedback interventions that are offered to students on a voluntary basis may not have a measurable impact on problem drinking. TRIAL REGISTRATION ClinicalTrials.gov: NCT01521078.Support to CAMH for salary of scientists and infrastructure has been provided by the Ontario Ministry of Health and Long Term Care

EVA Suit Microbial Leakage Investigation Project

The objective of this project is to collect microbial samples from various EVA suits to determine how much microbial contamination is typically released during simulated planetary exploration activities. Data will be released to the planetary protection and science communities, and advanced EVA system designers. In the best case scenario, we will discover that very little microbial contamination leaks from our current or prototype suit designs, in the worst case scenario, we will identify leak paths, learn more about what affects leakage--and we'll have a new, flight-certified swab tool for our EVA toolbox

Tracking large carnivore dispersal using isotopic clues in claws: An application to cougars across the Great Plains

1. Cougar (Puma concolor) populations, like other large carnivores, have increased during recent decades and may be recolonizing their former ranges in Midwestern North America. The dispersal routes taken by these animals from established populations are unknown and insight into these movements would facilitate their conservation and management. 2. We inferred the origin and migration route of four dispersing cougars using stable hydrogen (δD) and carbon (δ13C) isotope values along one of their claws. We compared isotopic variations within claws to regional and large-scale isoscapes of δD and δ13C values in prey species. Using a likelihood-based assignment approach, we predicted the most likely dispersal route of each cougar (among several least-cost dispersal paths to potential source populations) in a chronological sequence dating back from its final location. 3. Our model predicted the origin of a radio-collared short-distance disperser and inferences about the most likely dispersal corridors for two long-distance dispersers matched reported information from re-sighting events and genetic investigations. 4. Insights about the most likely migration corridors may help identify critical areas and guide future conservation efforts of cougars and other large carnivores. We encourage managers to extend regional isoscapes based on sedentary prey species as they prove to be valuable tools in isotopic tracking of long-distance migration. 5. Our isotopic approach may be extended to other metabolically inert tissues that grow continuously, to investigate dispersal paths of species of interest, providing that individuals disperse across known isotopically structured landscapes

Sexual differentiation of the zebra finch song system: potential roles for sex chromosome genes

Abstract Background Recent evidence suggests that some sex differences in brain and behavior might result from direct genetic effects, and not solely the result of the organizational effects of steroid hormones. The present study examined the potential role for sex-biased gene expression during development of sexually dimorphic singing behavior and associated song nuclei in juvenile zebra finches. Results A microarray screen revealed more than 2400 putative genes (with a false discovery rate less than 0.05) exhibiting sex differences in the telencephalon of developing zebra finches. Increased expression in males was confirmed in 12 of 20 by qPCR using cDNA from the whole telencephalon; all of these appeared to be located on the Z sex chromosome. Six of the genes also showed increased expression in one or more of the song control nuclei of males at post-hatching day 25. Although the function of half of the genes is presently unknown, we have identified three as: 17-beta-hydroxysteroid dehydrogenase type IV, methylcrotonyl-CoA carboxylase, and sorting nexin 2. Conclusion The data suggest potential influences of these genes in song learning and/or masculinization of song system morphology, both of which are occurring at this developmental stage

Differential proteome analysis of extracellular vesicles from breast cancer cell lines by chaperone affinity enrichment

The complexity of human tissue fluid precludes timely identification of cancer biomarkers by immunoassay or mass spectrometry. An increasingly attractive strategy is to primarily enrich extracellular vesicles (EVs) released from cancer cells in an accelerated manner compared to normal cells. The Vn96 peptide was herein employed to recover a subset of EVs released into the media from cellular models of breast cancer. Vn96 has affinity for heat shock proteins (HSPs) decorating the surface of EVs. Reflecting their cells of origin, cancer EVs displayed discrete differences from those of normal phenotype. GELFrEE LC/MS identified an extensive proteome from all three sources of EVs, the vast majority having been previously reported in the ExoCarta database. Pathway analysis of the Vn96-affinity proteome unequivocally distinguished EVs from tumorigenic cell lines (SKBR3 and MCF-7) relative to a non-tumorigenic source (MCF-10a), particularly with regard to altered metabolic enzymes, signaling, and chaperone proteins. The protein data sets provide valuable information from material shed by cultured cells. It is probable that a vast amount of biomarker identities may be collected from established and primary cell cultures using the approaches described here

Tears in your beer: Gender differences in coping drinking motives, depressive symptoms and drinking

This study evaluates associations between coping drinking motives (CDM; drinking to regulate negative affect), depressive symptoms, and drinking behavior and extends the literature by also taking into account gender differences. Two hundred forty-three college students (Mean age = 22.93, SD = 6.29, 82% female) participated. Based on previous research, we expected that CDM would be positively associated with drinking and problems, particularly among those higher in depressive symptoms, as individuals experiencing higher levels of negative affect (i.e. depressive symptoms) and who drink to cope are likely to drink more and experience more alcohol-related problems. Lastly, based on established gender differences, we expected that CDM would be positively associated with drinking and problems, especially among females higher in depressive symptoms. Unexpectedly, findings suggested that CDMs were positively related to peak drinking, especially among those lower in depressive symptoms. Results further revealed a significant three-way interaction between CDM, depressive symptoms, and gender when predicting alcohol-related problems and drinking frequency. Specifically, we found that CDM were more strongly associated with problems among women who were lower in depressive symptoms; whereas CDM were more strongly associated with problems among men who were higher in depressive symptoms. These findings offer a more comprehensive depiction of the relationship between depressive symptoms, CDM, and drinking behavior by taking into account the importance of gender differences. These results provide additional support for considering gender when designing and implementing alcohol intervention strategies