8,649 research outputs found

    Intolerable Masculinity: Screening Men\u27s Shame and Embracing Curious Futures

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    This thesis argues that to critique hegemonic masculinity and patriarchy in good faith, film and television must focus on the futures created through men’s ethical action in the present, rather than inert displays of men’s horrific behaviors that rely on audience shame as a tool for reclaiming men’s pride. Men’s freedom to change their situation is introduced through Manon Garcia’s (2022) notion of masculinity as an “impasse,” preventing men from authentic connection with others. This concept is furthered using David Buchbinder (2013), with the television examples Mad Men (Weiner 2007-2015) and Black Mirror (Brooker 2011-2023) each presenting a different masculine reaction to the notion of men’s responsibility. Following this foundation of men’s situation as constructed and therefore open to change, this thesis presents contemporary films which appear to critique men’s socially significant status, but instead obscure their responsibility to change through a performance of shame. Referencing Sara Ahmed’s (2014) study of national performances of shame alongside Jacques Rancière’s (2021) notion of the intolerable image, men’s shame over their past actions is critiqued as disguising men’s responsibility, and drawing attention away from women’s experiences of oppression by men. Men (Garland 2022) and The Power of the Dog (Campion 2021) serve as examples, representing an extreme display of masculine shame in the former, and a stronger yet incomplete critique of men’s harmful behaviors in the latter. Finally, this thesis continues with Rancière, as well as Simone de Beauvoir’s (2015) notion of ambiguity, to examine contemporary films which inspire curiosity in the spectator over how men might act ethically. This curiosity is a refusal of the inward turn of shame, and is vi crucial to the analysis of Aftersun (Wells 2022) and The Green Knight (Lowery 2021), films which explore men’s ambiguous situation and freedom to act in the present, without indulging in shame as a means of reclaiming men’s prid

    Project Shearwater Ground Effect UAV

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    The Shearwater unmanned aerial vehicle is a maritime fixed-wing drone that is designed to use ground effect force generated between the aircraft and a body of water to efficiently propel itself near the surface of a body of water. Shearwater features a virtual reality pilot interface and will act as a hybrid underwater vehicle that will eventually be able to operate both above and beneath the ocean’s surface. The Shearwater team developed existing design work to produce major subsystems that culminated in a flyable functioning prototype. An existing airframe was updated with working control surfaces tested in simulation and in practice, an electrical control system, and a working virtual reality (VR) pilot view. The Shearwater team tested a practical prototype and developed an optimized virtual reality command and control system

    Developing Change Management Aspects Of ERP Implementation Process Models

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    ERP systems implementation projects continue to be troubled by failures for which user resistance has constantly been identified as the main reason. Whilst existing IS research has provided a good understanding of why ERP implementations trigger user resistance, there is less guidance offered to those seeking to successfully negotiate user resistance during the ERP implementation process. This paper provides a conceptual framework designed to provide project managers with a change management approach to ERP implementation. Specifically, the paper provides the basis for applying change management concepts and tools within the specific context of a technically-driven enterprise-wide implementation process. By integrating concepts from two distinct disciplines (IS and organisational behaviour) into a coherent framework, this paper aims to refine existing models of ERP implementation

    Promoting family strengths (1999)

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    "Human relations.""Information from Human Environmental Sciences Extension."New 10/99/5M

    Promoting family strengths (2001)

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    In our society, families take on many different structures. Although they may be formed in different ways, most families accomplish similar tasks, such as childbearing, providing for members' basic needs, providing emotional support, socializing members, establishing family traditions and delegating responsibility. By accomplishing these tasks, families influence the way individuals and society function. Few other social institutions have such a great impact on society. This profound influence makes evident the importance of strengthening families.Reviewed April 2001--MU Extension website (viewed June 2019)New 10/99/5M.--Page 4

    Adapted Pool Cue

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    Our primary goal was to develop an adaptive device to allow a user with limited upper body mobility to more effectively play a game of pool. Within this goal it was important to design around the concept of a least restrictive environment, in order to provide the user with as close to a standard pool playing experience as possible. The device was designed to specifically meet the needs of John Lee, an Assistive Technology Specialist at Cal Poly\u27s Disability Resource Center. Mr. Lee has muscular dystrophy, which limits his upper and lower body mobility and currently requires his use of a wheelchair. Research into the specific needs of our customer, current products, and pool game elements was performed to better understanding of the project goals. From this research and discussion with John Lee, customer requirements and engineering specifications were developed. These were then used to guide the design development process. Several ideation techniques were used, and concepts for a bridge mechanism and supporting bases were created. A rough prototype was developed to test the concepts before our final design direction was decided. Our final design acts as a robust bridge device with a self-supporting base that constrains the path of the pool cue to a set path, allowing the user to focus their effort on providing power to the shot. The base can be rolled around the table, and stabilizing posts are lowered through a cable system when the shot is being made to prevent the base from sliding. The shooting mechanism features horizontal and vertical angle adjustment to allow for proper positioning of the cue, as well as a small cue stop to adjust the allowable travel of the pool cue. A vertical height adjustment is also present to allow the mechanism to reach over the edge of the pool table and for special high angle shots. The shooting mechanism itself features fixed and sliding rollers that act as a modified pool bridge, limiting travel of the pool cue to one axis of motion. The top part of the device can be separated from the base and clamped to the upright post for easier transport. These design choices allow the device to be compatible with any size regulation pool cue. Engineering analysis was performed to select materials and size components for the final device. Parts were specified and costs recorded to keep within the program budget. The device was then manufactured to the specifications shown in the included technical drawings, and testing was performed to verify that the final product met the design requirements. The overall experience was successful, and the final product received strong approval from John Lee. Recommendations for potential future improvement of both manufacturing and design of the device are included, as are as tips for device operation

    DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML

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    <b>Background</b>. Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are neoplastic disorders of hematopoietic stem cells. DNA methyltransferase inhibitors (DNMTi), 5-azacytidine (AzaC) and 5-aza-2’-deoxycytidine (Decitabine), benefit some MDS/AML patients. However, the role of DNMTi-induced DNA hypomethylation in regulation of gene expression in AML is unclear.<p></p> <b>Results. </b> We compared the effects of AzaC on DNA methylation and gene expression using whole-genome single-nucleotide bisulfite-sequencing (WGBS) and RNA-sequencing in OCI-AML3 (AML3) cells. For data analysis, we used an approach recently developed for discovery of differential patterns of DNA methylation associated with changes in gene expression, that is tailored to single-nucleotide bisulfite-sequencing data (Washington University Interpolated Methylation Signatures (WIMSi)). By this approach, a subset of genes upregulated by AzaC was found to be characterized by AzaC-induced signature methylation loss flanking the transcription start site. These genes are enriched for genes increased in methylation and decreased in expression in AML3 cells compared to normal hematopoietic stem and progenitor cells. Moreover, these genes are preferentially upregulated by Decitabine in human primary AML blasts, and control cell proliferation, death and development. <p></p> <b>Conclusions.</b> Our WGBS and WIMSi data analysis approach has identified a set of genes whose is methylation and silencing in AML is reversed by DNMTi. These genes are good candidates for direct regulation by DNMTi, and their reactivation by DNMTi may contribute to therapeutic activity. This study also demonstrates the ability of WIMSi to reveal relationships between DNA methylation and gene expression, based on single-nucleotide bisulfite-sequencing and RNA-seq data.<p></p&gt

    Tonic and phasic effects of reward on the pupil:implications for locus coeruleus function

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    The locus coeruleus (LC), a nucleus in the pons of the brainstem, plays a significant role in attention and cognitive control. Here, we use an adapted auditory oddball paradigm and measured the pupil dilation response, to provide a marker of LC activity in humans. In Experiment 1, we show event-related pupil responses to rare auditory events which were further elevated by task relevant. In Experiment 2, by asking participants to silently count the number of oddballs, we demonstrated that the task-relevance elevation was not a result of the generation or execution of the manual response. In Experiment 3, we observed two separate effects of reward on the pupil response. First, we found an overall increase in pupil area in the high compared to the low-reward blocks: a sustained effect reminiscent of the tonic changes that occur in LC. Second, we found elevated event-related pupil responses to behaviourally relevant stimuli in the high-reward condition compared with the low-reward condition, consistent with phasic changes in LC in response to a stimulus. These results highlight the complexity of the relationship between the pupil response and reward, and the inferred role of LC in both top-down and bottom-up cognitive control
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