Public or private religiosity: which Is protective for adolescent substance use and by what pathways?

While it is well understood that adolescent religiosity is associated with the use and abuse of licit and illicit substances, few studies have revealed the pathways through which religiosity buffers youth against involvement in such behavior. The aim of this study is to examine the complexity of the relationships between religiosity, sensation seeking, injunctive norms, and adolescent substance use. Using a national sample of adolescents (N = 18,614), negative binomial regression and path analysis were used to examine the various components of the relationship between religiosity and the use of cigarettes, alcohol, and marijuana. Results indicate that private religiosity moderates the relationship between key risk factors and substance use. Public and private religiosity were associated with tolerant injunctive substance use norms which, in turn, were associated with substance use. Implications for research and theory related to religiosity and adolescent substance use are discussed

Factors Influencing Consumer Likelihood of Purchasing a Flexible-Fuel or Hybrid Automobile

Developing fuels and vehicles that reduce our reliance on fossil fuels has become a priority due to the threat of global climate change and desire for reduced dependence on oil imports. Flexible-fuel vehicles that can run on ethanol/gasoline blends of up to 85% ethanol and hybrid electric vehicles present two such opportunities. While production of both flexible-fuel and hybrid vehicles is increasing, there is still a great deal of uncertainty about how consumers will respond to these products. To address this uncertainty, data was collected through an online survey of automobile owners that asked respondents how likely they were to choose either a flexible-fuel or hybrid vehicle as their next vehicle. A bivariate probit model was used to jointly analyze responses to these two questions. The results show that, while there was some overlap in the factors correlated with perceived likelihood of choosing one of these two types of automobiles, there were also clear differences. These results should benefit policymakers, marketers and academics seeking a better understanding of the respective markets for these vehicles.flexible-fuel vehicles, ethanol, E85, hybrid electric vehicles, Demand and Price Analysis, Environmental Economics and Policy, Resource /Energy Economics and Policy,

Factors Influencing Willingness-to-Pay for the Energy Star Label

In the United States, nearly 17 percent of greenhouse gas emissions come from residential energy use. Increases in energy efficiency for the residential sector can generate significant energy savings and emissions reductions. Consumer labels, such as USEPA’s Energy Star, promote conservation by providing consumers with information on energy usage for household appliances. This study examines how the Energy Star label affects consumer preferences for refrigerators. An online survey of a national sample of adults suggest that consumers are, on average, willing to pay an extra $249.82 to$349.30 for a refrigerator that has been awarded the Energy Star label. Furthermore, the results provide evidence that willingness to pay was motivated by both private (energy cost savings) and public (environmental) benefits.Energy Star, willingness-to-pay, eco-label, Consumer/Household Economics, Demand and Price Analysis, Environmental Economics and Policy,

Modeling the aggregated exposure and responses of bowhead whales Balaena mysticetus to multiple sources of anthropogenic underwater sound

Potential responses of marine mammals to anthropogenic underwater sound are usually assessed by researchers and regulators on the basis of exposure to a single, relatively loud sound source. However, marine mammals typically receive sounds from multiple, dynamic sources. We developed a method to aggregate modeled sounds from multiple sources and estimate the sound levels received by individuals. To illustrate the method, we modeled the sound fields of 9 sources associated with oil development and estimated the sound received over 47 d by a population of 10 000 simulated bowhead whales Balaena mysticetus on their annual migration through the Alaskan Beaufort Sea. Empirical data were sufficient to parameterize simulations of the distribution of individual whales over time and their range of movement patterns. We ran 2 simulations to estimate the sound exposure history and distances traveled by bowhead whales: one in which they could change their movement paths (avert) in response to set levels of sound and one in which they could not avert. When animals could not avert, about 2% of the simulated population was exposed to root mean square (rms) sound pressure levels (SPL) \u3e = 180 dB re 1 mu Pa, a level that regulators in the U.S. often associate with injury. When animals could avert from sound levels that regulators often associate with behavioral disturbance (rms SPL \u3e 160 dB re 1 mu Pa), \u3c 1% of the simulated population was exposed to levels associated with injury. Nevertheless, many simulated bowhead whales received sound levels considerably above ambient throughout their migration. Our method enables estimates of the aggregated level of sound to which populations are exposed over extensive areas and time periods

Observations on the Ice-Breaking and Ice Navigation Behavior of Migrating Bowhead Whales (Balaena Mysticetus) near Point Barrow, Alaska, Spring 1985

During a four-day period from 28 April to 1 May 1985, we observed bowhead whales breaking up through sea ice in order to breathe. Our observations were made from grounded sea ice approximately 10 km northeast of Point Barrow, Alaska, during the spring bowhead migration (14 April to 10 June). From acoustic and visual data, it was estimated that 665 whales passed the observation perches during this four-day period. However, only 117(17%) whales were seen. The remaining whales either passed underneath the ice or were beyond the range of the visual observers. Whales used their heads, in the area of the blowholes, to push up against the ice (18 cm maximum thickness) and fracture it, creating a hummock of ice in which they were able to respire. Often during such breathing episodes, even at distances of only several hundred meters, the animal was not seen but its blows were clearly audible to the visual observers. Acoustic tracking of whales showed they avoided a large multi-year ice floe seaward of the observation perch. We hypothesize that bowheads use their calls to assess the thickness of ice in their migratory path. In assessing their calls, we suggest the whales can avoid areas where the ice is too thick to break through (to breath) and/or too thick to provide clearance for them to swim beneath.Key words: Balaena mysticetus, Point Barrow, bowhead whale, ice breaking, behavior, sea ice, singer, acoustic, anatomy, censusMots clés: Balaena mysticetus, Point Barrow, baleine franche, casser la glace, comportement, glace de mer, chanteuse, acoustique, anatomie, dénombremen

Primary adenoid cystic carcinoma of the breast: case report and review of the literature

Adenoid cystic carcinoma (ACC) of the breast is a rare neoplasm accounting for 0.1% of all breast carcinomas, and presenting most commonly as a painful breast mass. In contrast to the aggressive nature of ACC at other sites, ACC of the breast has a favorable prognosis, lymph node involvement or distant metastases seldom occur. Treatment is basically of simple mastectomy. Chemotherapy, radiation and hormonal treatment have been infrequently used and evaluated. We report a case of ACC of the breast managed with mastectomy and review the literature

Characterization of the nodulation plasmid encoded chemoreceptor gene mcpG from Rhizobium leguminosarum

BACKGROUND: In general, chemotaxis in Rhizobium has not been well characterized. Methyl accepting chemotaxis proteins are sensory proteins important in chemotaxis of numerous bacteria, but their involvement in Rhizobium chemotaxis is unclear and merits further investigation. RESULTS: A putative methyl accepting chemotaxis protein gene (mcpG) of Rhizobium leguminosarum VF39SM was isolated and characterized. The gene was found to reside on the nodulation plasmid, pRleVF39d. The predicted mcpG ORF displayed motifs common to known methyl-accepting chemotaxis proteins, such as two transmembrane domains and high homology to the conserved methylation and signaling domains of well-characterized MCPs. Phenotypic analysis of mcpG mutants using swarm plates did not identify ligands for this putative receptor. Additionally, gene knockouts of mcpG did not affect a mutant strain's ability to compete for nodulation with the wild type. Notably, mcpG was found to be plasmid-encoded in all strains of R. leguminosarum and R. etli examined, though it was found on the nodulation plasmid only in a minority of strains. CONCLUSIONS: Based on sequence homology R. leguminosarum mcpG gene codes for a methyl accepting chemotaxis protein. The gene is plasmid localized in numerous Rhizobium spp. Although localized to the sym plasmid of VF39SM mcpG does not appear to participate in early nodulation events. A ligand for McpG remains to be found. Apparent McpG orthologs appear in a diverse range of proteobacteria. Identification and characterization of mcpG adds to the family of mcp genes already identified in this organism

Transitions in Care in a Nationally Representative Sample of Older Americans with Dementia

OBJECTIVES: To describe transitions in care for older adults with dementia identified from a nationally representative cohort and to describe transition rates in those with more-severe levels of cognitive and functional impairment. DESIGN: Longitudinal cohort study. SETTING: Health and Retirement Study (HRS). PARTICIPANTS: HRS respondents aged 65 and older whose survey data were linked with Medicare claims from 1999 to 2008 (N = 16,186). MEASUREMENTS: Transitions in care between home, home with formal services, hospital, and nursing facility care; cognitive function; activities of daily living; and mortality. RESULTS: The 3,447 (21.3%) HRS subjects who were ever diagnosed with dementia experienced frequent transitions. Of subjects transitioning from a hospital stay, 52.2% returned home without home care services, and 33.8% transitioned to a nursing facility. Of subjects transitioning from a nursing facility, 59.2% transitioned to the hospital, and 25.3% returned home without services. There were 2,139 transitions to death, and 58.7% of HRS subjects with dementia died at home. Even in persons with moderate to severe dementia, multiple transitions in care were documented, including transitions from the hospital to home and back to the hospital. CONCLUSION: In this nationally representative sample of older adults, subjects diagnosed with dementia experience frequent transitions. Persons with dementia who are cared for at home and who transition back to home often have moderate to severe impairments in function and cognition

Attention and motor profiles in children with developmental coordination disorder: A neuropsychological and neuroimaging investigation

AIM: This study aimed to (1) quantify attention and executive functioning in children with developmental coordination disorder (DCD), (2) assess whether some children with DCD are more likely to show attention difficulties, and (3) characterize brain correlates of motor and attention deficits. METHOD: Fifty-three children (36 with DCD and 17 without) aged 8 to 10 years underwent T1-weighted and diffusion-weighted magnetic resonance imaging, and standardized attention and motor assessments. Parents completed questionnaires of executive functioning and symptoms of inattention and hyperactivity. We assessed regional cortical thickness and surface area, and cerebellar, callosal, and primary motor tract structure. RESULTS: Analyses of covariance and one-sample t-tests identified impaired attention, non-motor processing speed, and executive functioning in children with DCD, yet partial Spearman's rank correlation coefficients revealed these were unrelated to one another or the type or severity of the motor deficit. Robust regression analyses revealed that cortical morphology in the posterior cingulate was associated with both gross motor skills and inattentive symptoms in children with DCD, while gross motor skills were also associated with left corticospinal tract (CST) morphology. INTERPRETATION: Children with DCD may benefit from routine attention and hyperactivity assessments. Alterations in the posterior cingulate and CST may be linked to impaired forward modelling during movements in children with DCD. Overall, alterations in these regions may explain the high rate of non-motor impairments in children with DCD

Errors in self-reports of health services use: impact on alzheimer disease clinical trial designs

BACKGROUND: Most Alzheimer disease clinical trials that compare the use of health services rely on reports of caregivers. The goal of this study was to assess the accuracy of self-reports among older adults with Alzheimer disease and their caregiver proxy respondents. This issue is particularly relevant to Alzheimer disease clinical trials because inaccuracy can lead both to loss of power and increased bias in study outcomes. METHODS: We compared respondent accuracy in reporting any use and in reporting the frequency of use with actual utilization data as documented in a comprehensive database. We next simulated the impact of underreporting and overreporting on sample size estimates and treatment effect bias for clinical trials comparing utilization between experimental groups. RESULTS: Respondents self-reports have a poor level of accuracy with κ-values often below 0.5. Respondents tend to underreport use even for rare events such as hospitalizations and nursing home stays. In analyses simulating underreporting and overreporting of varying magnitude, we found that errors in self-reports can increase the required sample size by 15% to 30%. In addition, bias in the reported treatment effect ranged from 3% to 18% due to both underreporting and overreporting errors. CONCLUSIONS: Use of self-report data in clinical trials of Alzheimer disease treatments may inflate sample size needs. Even when adequate power is achieved by increasing sample size, reporting errors can result in a biased estimate of the true effect size of the intervention