882 research outputs found
Deaf Inclusion and Accessibility in the Dance Field
Over the past ten years, the dance field in the United States has shifted towards practicing diversity and inclusion. However, there are still underrepresented groups in dance, such as the Deaf community. There is a current lack of pedagogical content to help dance teachers and choreographers be inclusive to Deaf dancers. This research addresses the gap by discussing issues and access for Deaf and hard-of-hearing (HOH) dancers in the dance classroom and on stage. To do so, I present a literature review and analysis of current scholarship with a goal of bringing awareness to the current lack of accessibility to dance classes for Deaf dancers and promoting dance instructors and choreographers to be more inclusive in their teaching styles. To begin, the disability and culture of deafness is discussed. Since the Deaf community does not see deafness as a disadvantage but rather as a cultural experience, it is important to consider their views on deafness and their culture’s representation. Then, I focus on pedagogical efforts in the dance field and on the incorporation of American Sign Language (ASL) into dance choreography. When ASL and dance are viewed as two movement-based expressions, the two can be combined in creative ways. For the future, I would like to see an increase of accessibility in dance classrooms for Deaf dancers. This research covers strategies that allow dance teachers to plan classes and choreography with more inclusion and lays the foundation for future research
DDO 88: A Galaxy-Sized Hole in the Interstellar Medium
We present an HI and optical study of the gas-rich dwarf irregular galaxy DDO
88. Although DDO 88's global optical and HI parameters are normal for its
morphological type, it hosts a large (3 kpc diameter) and unusually complete
ring of enhanced HI emission. The gas ring is located at approximately
one-third of the total HI radius and one-half the optically-defined Holmberg
radius, and contains 30% of the total HI of the galaxy. The ring surrounds a
central depression in the HI distribution, so it may be a shell formed by a
starburst episode. However, the UBV colors in the HI hole are not bluer than
the rest of the galaxy as would be expected if an unusual star-forming event
had taken place there recently, but there is an old (~1-3 Gyr), red cluster
near the center of the hole that is massive enough to have produced the hole in
the HI. An age estimate for the ring, however, is uncertain because it is not
observed to be expanding. An expansion model produces a lower estimate of 0.5
Gyr, but the presence of faint star formation regions associated with the ring
indicate a much younger age. We also estimate that the ring could have
dispersed by now if it is older than 0.5 Gyr. This implies that the ring is
younger than 0.5 Gyr. A younger age would indicate that the red cluster did not
produce the hole and ring. If this ring and the depression in the gas which it
surrounds were not formed by stellar winds and supernovae, this would indicate
that some other, currently unidentified, mechanism is operating.Comment: 44 pages; 16 figures. To appear in AJ, January 2005. Available from
ftp.lowell.edu, cd pub/dah/papers/d88 and http://www.fiu.edu/~simpsonc/d8
Severity of Depression Predicts Remission Rates Using Transcranial Magnetic Stimulation
Background: Multiple factors likely impact response and remission rates in the treatment of depression with repetitive transcranial magnetic stimulation (rTMS). Notably the role of symptom severity in outcomes with rTMS is poorly understood.Objective/Hypothesis: This study investigated the predictors of achieving remission in patients suffering from depression who receive ≥3 rTMS treatments per week. Methods: Available data on 41 patients treated at Walter Reed National Military Medical Center from 2009 to 2014 were included for analysis. Patients received a range of pulse sequences from 3,000 to 5,000 with left sided or bilateral coil placement. Primary outcome measures were total score on the Patient Health Questionnaire (PHQ-9) or the Quick Inventory of Depressive Symptomatology—Self Rated (QIDS-SR). Remission was defined as a total score less than five, and response was defined as a 50% decrease in the total score on both outcome metrics. Outcomes in patients diagnosed as suffering from mild or moderate depression were compared to those suffering from severe depression. Results: Of the 41 patients receiving treatment, 16 reached remission by the end of treatment. Remission rate was associated with the initial severity of depression, with patients with mild or moderate depression reaching remission at a significantly higher rate than those with severe depression. Total number of rTMS sessions or length of treatment were not predictors of remission. Conclusion: Patients with a baseline level of depression characterized as mild or moderate had significantly better outcomes following rTMS compared to patients with severe depression
Service use of older people who participate in primary care health promotion: a latent class analysis
© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Abstract Background Recruiting patients to health promotion programmes who will benefit is crucial to success. A key policy driver for health promotion in older people is to reduce health and social care use. Our aim was to describe service use among older people taking part in the Multi-dimensional Risk Appraisal for Older people primary care health promotion programme. Methods A random sample of 1 in 3 older people (≥65 years old) was invited to participate in the Multi-dimensional Risk Appraisal for Older people project across five general practices in London and Hertfordshire. Data collected included socio-demographic characteristics, well-being and functional ability, lifestyle factors and service use. Latent class analysis (LCA) was used to identify groups based on use of the following: secondary health care, primary health care, community health care, paid care, unpaid care, leisure and local authority resources. Differences in group characteristics were assessed using univariate logistic regression, weighted by probability of class assignation and clustered by GP practice. Results Response rate was 34% (526/1550) with 447 participants presenting sufficient data for analysis. LCA using three groups gave the most meaningful interpretation and best model fit. About a third (active well) were fit and active with low service use. Just under a third (high NHS users) had high impairments with high primary, secondary and community health care contact, but low non-health services use. Just over a third (community service users) with high impairments used community health and other services without much hospital use. Conclusion Older people taking part in the Multi-dimensional Risk Appraisal for Older people primary care health promotion can be described as three groups: active well, high NHS users, and community service users.Peer reviewe
Combined linkage and association analysis of classical Hodgkin lymphoma
Peer reviewedPublisher PD
Overcoming barriers to engaging socio-economically disadvantaged populations in CHD primary prevention: a qualitative study
<p><b>Background:</b> Preventative medicine has become increasingly important in efforts to reduce the burden of chronic disease in industrialised countries. However, interventions that fail to recruit socio-economically representative samples may widen existing health inequalities. This paper explores the barriers and facilitators to engaging a socio-economically disadvantaged (SED) population in primary prevention for coronary heart disease (CHD).</p>
<p><b>Methods:</b> The primary prevention element of Have a Heart Paisley (HaHP) offered risk screening to all eligible individuals. The programme employed two approaches to engaging with the community: a) a social marketing campaign and b) a community development project adopting primarily face-to-face canvassing. Individuals living in areas of SED were under-recruited via the social marketing approach, but successfully recruited via face-to-face canvassing. This paper reports on focus group discussions with participants, exploring their perceptions about and experiences of both approaches.</p>
<p><b>Results:</b> Various reasons were identified for low uptake of risk screening amongst individuals living in areas of high SED in response to the social marketing campaign and a number of ways in which the face-to-face canvassing approach overcame these barriers were identified. These have been categorised into four main themes: (1) processes of engagement; (2) issues of understanding; (3) design of the screening service and (4) the priority accorded to screening. The most immediate barriers to recruitment were the invitation letter, which often failed to reach its target, and the general distrust of postal correspondence. In contrast, participants were positive about the face-to-face canvassing approach. Participants expressed a lack of knowledge and understanding about CHD and their risk of developing it and felt there was a lack of clarity in the information provided in the mailing in terms of the process and value of screening. In contrast, direct face-to-face contact meant that outreach workers could explain what to expect. Participants felt that the procedure for uptake of screening was demanding and inflexible, but that the drop-in sessions employed by the community development project had a major impact on recruitment and retention.</p>
<p><b>Conclusion:</b> Socio-economically disadvantaged individuals can be hard-to-reach; engagement requires strategies tailored to the needs of the target population rather than a population-wide approach.</p>
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The function-dominance correlation drives the direction and strength of biodiversity-ecosystem functioning relationships
Community composition is a primary determinant of how biodiversity change influences ecosystem functioning and, therefore, the relationship between biodiversity and ecosystem functioning (BEF). We examine the consequences of community composition across six structurally realistic plant community models. We find that a positive correlation between species' functioning in monoculture versus their dominance in mixture with regard to a specific function (the "function-dominance correlation") generates a positive relationship between realised diversity and ecosystem functioning across species richness treatments. However, because realised diversity declines when few species dominate, a positive function-dominance correlation generates a negative relationship between realised diversity and ecosystem functioning within species richness treatments. Removing seed inflow strengthens the link between the function-dominance correlation and BEF relationships across species richness treatments but weakens it within them. These results suggest that changes in species' identities in a local species pool may more strongly affect ecosystem functioning than changes in species richness
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The inositol-3-phosphate synthase biosynthetic enzyme has distinct catalytic and metabolic roles
Inositol levels, maintained by the biosynthetic enzyme inositol-3-phosphate synthase (Ino1), are altered in a range of disorders including bipolar disorder and Alzheimer's disease. To date, most inositol studies have focused on the molecular and cellular effects of inositol depletion without considering Ino1 levels. Here we employ a simple eukaryote, Dictyostelium, to demonstrate distinct effects of loss of Ino1 and inositol depletion. We show that loss of Ino1 results in inositol auxotrophy that can only be partially rescued by exogenous inositol. Removal of inositol supplementation from the ino1- mutant results in a rapid 56% reduction in inositol levels, triggering the induction of autophagy, reduced cytokinesis and substrate adhesion. Inositol depletion also caused a dramatic generalised decrease in phosphoinositide levels that was rescued by inositol supplementation. However, loss of Ino1 triggered broad metabolic changes consistent with the induction of a catabolic state that was not rescued by inositol supplementation. These data suggest a metabolic role for Ino1 independent of inositol biosynthesis. To characterise this role, an Ino1 binding partner containing SEL1L1 domains (Q54IX5) was identified with homology to mammalian macromolecular complex adaptor proteins. Our findings therefore identify a new role for Ino1, independent of inositol biosynthesis, with broad effects on cell metabolism
Striking the right balance in right whale conservation
Author Posting. © The Authors, 2009. This article is posted here by permission of NRC Research Press for personal use, not for redistribution. The definitive version was published in Canadian Journal of Fisheries and Aquatic Sciences 66 (2009): 1399-1403, doi:10.1139/F09-115.Despite many years of study and protection, the North Atlantic right whale (Eubalaena glacialis) remains on the brink of extinction. There is a crucial gap in our understanding of their habitat use in the migratory corridor along the eastern seaboard of the United States. Here, we characterize habitat suitability in migrating right whales in relation to depth, distance to shore, and the recently enacted ship speed regulations near major ports. We find that the range of suitable habitat exceeds previous estimates and that, as compared with the enacted 20 nautical mile buffer, the originally proposed 30 nautical mile buffer would protect more habitat for this critically endangered species.This work was supported in part by SERDP/DoD grant
W912HQ-04-C-0011 to A.J. Read and P.N. Halpin as well
as a James B. Duke Fellowship and a Harvey L. Smith Dissertation
Year Fellowship to R.S. Schick
Humidified and standard oxygen therapy in acute severe asthma in children (HUMOX): A pilot randomised controlled trial.
BackgroundOxygen (O2) is a mainstay of treatment in acute severe asthma but how it is administered varies widely. The objectives were to examine whether a trial comparing humidified O2 to standard O2 in children is feasible, and specifically to obtain data on recruitment, tolerability and outcome measure stability.MethodsHeated humidified, cold humidified and standard O2 treatments were compared for children (2-16 years) with acute severe asthma in a multi-centre, open, parallel, pilot randomised controlled trial (RCT). Multiple outcomes were assessed.ResultsOf 258 children screened, 66 were randomised (heated humidified O2 n = 25; cold humidified O2 n = 21; standard O2 n = 20). Median (IQR) length of stay (hours) in hospital was 37.9 (29.1), 52 (35.4) and 49.1 (29.7) for standard, heated humidified and cold humidified respectively and time (hours) on O2 was 15.9 (9.4), 13.6 (14.9) and 13.1 (14.9) for the three groups respectively. The mean (standard deviation) time (hours) taken to step down nebulised to inhaled treatment was 5.6 (14.3), 35.1 (28.2) and 32.7 (20.1). Asthma Severity Score decreased in all three groups similarly, although missing data prevented complete analysis. Humidified O2 was least well tolerated with eight participants discontinuing their randomised treatment early. An important barrier to recruitment was research nurse availability.ConclusionAlthough, the results of this pilot study should not be extrapolated beyond the study sample and inferential conclusions should not be drawn from the results, this is the first RCT to compare humidified and standard O2 therapy in acute severe asthmatics of any age. These findings and accompanying screening data show that a large RCT of O2 therapy is feasible. However, challenges associated with randomisation and data collection should be addressed in any future trial design
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