Preliminary results on Ontology-based Open Data Publishing

Despite the current interest in Open Data publishing, a formal and comprehensive methodology supporting an organization in deciding which data to publish and carrying out precise procedures for publishing high-quality data, is still missing. In this paper we argue that the Ontology-based Data Management paradigm can provide a formal basis for a principled approach to publish high quality, semantically annotated Open Data. We describe two main approaches to using an ontology for this endeavor, and then we present some technical results on one of the approaches, called bottom-up, where the specification of the data to be published is given in terms of the sources, and specific techniques allow deriving suitable annotations for interpreting the published data under the light of the ontology

First description of a histamine receptor of class 2 (HRH2) in a protochordate: expression during blastogenesis and role in regulation of ciliary beat frequency

Histaminergic receptors belong to the family of seven-transmembrane \u3b1-helix domain receptors classified in mammals into four distinct classes. Despite being widely studied in vertebrates, few data are available on the invertebrate receptors, with only predicted H1 and H2 sequences for non-chordate deuterostomes. We report the first transcript evidence of an H2 receptor for histamine in the colonial ascidian Botryllus schlosseri showing a high degree of conservation with HRH2 mammalian and other vertebrate orthologous proteins. The transcript and protein localisation during blastogenic development through in situ hybridisation and immunohistochemistry has been described. The mRNA expression appears first in the ciliary tissues of the alimentary system in filter-feeding adults and the buds, with a particular intensity in the pharynx. Transcription is activated very early, beginning from the inner layer of the disc of the secondary bud. From one generation to the next, the transcript signals become more and more intense at the level of the emergence of primordia of the branchial and peribranchial chambers and, finally, in the cells bordering the stigmata, dorsal lamina, and non-glandular ciliated zones of the endostyle. The translated H2 receptor appears as soon as the primordia of branchial and peribranchial chambers form in the secondary bud, and, in the primary buds, is found mainly in the protostigmata before the two layers of branchial and peribranchial epithelial tissue perforate to form the stigmata. In the adult zooid, the H2 receptor is expressed by ciliated mucous cells involved in food progression throughout the whole length of the alimentary canal. The observation of the effects of histamine and histamine-receptor antagonist (ranitidine) and agonist (dimaprit) drugs on explanted branchial tissue has provided confirmation concerning the receptor class and its role in regulating the ciliary beat frequency. The involvement in the local regulation of ciliary activity is of particular concern for evolutionary considerations because HRH2 seems to have been conserved in the pharynx and its developmental derivatives (e.g. upper respiratory tract and middle ear of mammals) during the evolution of chordates

The Jackiw-Pi model and its symmetries

The non-Abelian gauge model proposed by Jackiw and Pi, which generates an even-parity mass term in three space-time dimensions, is revisited in this letter. All the symmetries of the model are collected and established by means of BRS invariance and Slavnov-Taylor identity. The path for the perturbatively quantization of the Jackiw-Pi model, through the algebraic method of renormalization, is presented.Comment: 5 page

The Jackiw-Pi model: classical theory

The massive even-parity non-Abelian gauge model in three space-time dimensions proposed by Jackiw and Pi is studied at the tree-level. The propagators are computed and the spectrum consistency is analyzed, besides, the symmetries of the model are collected and established through BRS invariance and Slavnov-Taylor identity. In the Landau gauge, thanks to the antighost equations and the Slavnov-Taylor identity, two rigid symmetries are identified by means of Ward identities. It is presented here a promising path for perturbatively quantization of the Jackiw-Pi model and a hint concerning its possible quantum scale invariance is also pointed out.Comment: In honor of the 70th birthday of Prof. Olivier Piguet. 11 page

Isometric Equivalence of Isometries on Hp H^p

We consider a natural notion of equivalence for bounded linear operators on $H^p,$ for $p\neq 2.$ We determine which isometries of finite codimension are equivalent. For these isometries , we classify those which have the Crownover property

Insights on cytotoxic cells of the colonial ascidian Botryllus schlosseri

Morula cells (MCs) represent the most abundant circulating hemocyte of the compound ascidian Botryllus schlosseri. They are cytotoxic cells involved in the rejection reaction between contacting, genetically incompatible colonies. Upon the recognition of foreign substances, they degranulate and release their content, which contribute to the cell death along the contact borders. A major role in MC-related cytotoxicity is exerted by the enzyme phenoloxidase (PO) that converts polyphenol substrata to quinones which, then, polymerize to form melanins. During this reaction, reactive oxygen species are formed which are the cause of MC-related cytotoxicity. Here, we carried out new analyses to investigate further the nature of MC content and its role in cytotoxicity. Results confirm that PO is located inside MC vacuoles together with arylsulfatase, iron and polyphenols/quinones, the latter probably representing ready-to-use cytotoxic molecules, deriving from the oxidation of DOPA-containing proteins. In addition, small DOPA-containing peptides, called tunichromes, are also present inside MCs. MC degranulation and PO-mediated cytotoxicity are prevented by secretion inhibitors and by H89 and calphostin C. The observation that PO activity is always detectable in MCs in the absence of protease treatment, and its inhibition by sulfites and sulfates, suggest a non-classical pathway of PO modulation in botryllid ascidians

Non-integrability of measure preserving maps via Lie symmetries

We consider the problem of characterizing, for certain natural number $m$, the local $\mathcal{C}^m$-non-integrability near elliptic fixed points of smooth planar measure preserving maps. Our criterion relates this non-integrability with the existence of some Lie Symmetries associated to the maps, together with the study of the finiteness of its periodic points. One of the steps in the proof uses the regularity of the period function on the whole period annulus for non-degenerate centers, question that we believe that is interesting by itself. The obtained criterion can be applied to prove the local non-integrability of the Cohen map and of several rational maps coming from second order difference equations.Comment: 25 page

Electron-polaron--electron-polaron bound states in mass-gap graphene-like planar quantum electrodynamics: ss-wave bipolarons

A Lorentz invariant version of a mass-gap graphene-like planar quantum electrodynamics, the parity-preserving $U(1)\times U(1)$ massive QED$_3$, exhibits attractive interaction in low-energy electron-polaron--electron-polaron $s$-wave scattering, favoring quasiparticles bound states, the $s$-wave bipolarons.Comment: 6 pages, two figures, references adde