Tris(2,2′-bipyridine-κ2 N,N′)cobalt(III) tris­(oxalato-κ2 O 1,O 2)ferrate(III) mono­hydrate

The title compound, [Co(C10H8N2)3][Fe(C2O4)3]·H2O, con­sists of two discrete tris­(chelate) metal ions (CoIIIN6 and FeIIIO6 chromophores) and a water mol­ecule. The structure is highly symmetrical; the CoIII and FeIII ions occupy positions with site symmetry 3.2. The coordination polyhedra of the metal atoms have a nearly octa­hedral geometry with noticeable trigonal distortions. The Co—N and Fe—O bond lengths are equal by symmetry, viz. 1.981 (2) and 1.998 (4) Å, respectively. The cations and anions are arranged alternately along their threefold rotation axes parallel to [001], forming chains that are packed in a hexa­gonal manner. The water mol­ecules occupy voids between the chains. The crystal under investigation was an inversion twin

Hexa­kis­(dimethyl­formamide-κO)manganese(II) μ-oxido-bis­[trichlorido­ferrate(III)]

The title compound, [Mn(C3H7NO)6][Fe2Cl6O], was obtained unintentionally as a product of an attempted synthesis of heterometallic complexes with Schiff base ligands using manganese powder and FeCl3·6H2O as starting materials. In the [Fe2OCl6]2− anion, the O atom and the Fe atom occupy positions with site symmetry and 3, respectively, resulting in a linear Fe—O—Fe angle and a staggered conformation. The octa­hedrally surrounded cation (site symmetry ) and the [Fe2Cl6O]2− anion are alternately stacked along [001]

Direct synthesis and crystal structure of a novel tetranuclear Co2IIIFe2III Schiff base complex

The title compound, tetra(µ-2-3-(2-oxybenzylideneamino)-1-hydroxypropan-2-olato)-4-nitrophenolatedi-cobalt(III)-di-iron(III) dimethylsulfoxidehexasolvate, crystallizes in the monoclinic space group P21/c and represent the first example of heterometallic CoIII-FeIII complex with 3-((5-nitro-2-hydroxybenzylidene)amino)propane-1,2-diol/2-(((2,3-dihydroxy propyl)iminio)methyl)-4-nitrophenolate) - a hydroxyl rich Schiff base ligand which was obtained in situ. Crystal data for C52H74Cl2Co2Fe2N8O26S6 (M = 1720.01 g/mol): monoclinic, space group P21/c (no. 14), a = 16.353(3) Å, b = 15.234(2) Å, c = 15.201(3) Å, β = 113.99(2)°, V = 3460.0(12) Å3, Z = 2, T = 173(2) K, μ(MoKα) = 1.225 mm-1, Dcalc = 1.651 g/cm3, 14130 reflections measured (5.7° ≤ 2Θ ≤ 57.266°), 7748 unique (Rint = 0.1051, Rsigma = 0.2148) which were used in all calculations. The final R1 was 0.0914 (I > 2σ(I)) and wR2 was 0.2279 (all data). The metal ions have distorted octahedral coordination geometry and are joined in a tetranuclear {Co2Fe2(µ-O)6} core by O-bridging atoms from the ligand. There are numerous intermolecular interactions occurring between the components of the crystal: π-hole interaction between NO2···NO2 groups of the ligands, short S···S, O···O and C··· C interactions and weak and strong hydrogen bonds

Salinomycin Hydroxamic Acids: Synthesis, Structure, and Biological Activity of Polyether Ionophore Hybrids

The polyether ionophore salinomycin has recently gained attention due to its exceptional ability to selectively reduce the proportion of cancer stem cells within a number of cancer cell lines. Efficient single step strategies for the preparation of hydroxamic acid hybrids of this compound varying in N- and O-alkylation are presented. The parent hydroxamic acid, salinomycin-NHOH, forms both inclusion complexes and well-defined electroneutral complexes with potassium and sodium cations via 1,3-coordination by the hydroxamic acid moiety to the metal ion. A crystal structure of an cationic sodium complex with a noncoordinating anion corroborates this finding and, moreover, reveals a novel type of hydrogen bond network that stabilizes the head-to-tail conformation that encapsulates the cation analogously to the native structure. The hydroxamic acid derivatives display down to single digit micromolar activity against cancer cells but unlike salinomycin selective reduction of ALDH+ cells, a phenotype associate

Bis(μ-4-nitro-2-{[2-(oxidomethyl)phenyl]iminomethyl}phenolato)bis[chlorido(dimethyl sulfoxide)iron(III)] dimethyl sulfoxide disolvate

In the centrosymmetric dimeric title complex, [Fe2(C14H10N2O4)2Cl2(C2H6OS)2]·2C2H6OS, two {Fe(L)Cl(DMSO)} units (L is the tridentate ligand 4-nitro-2-{[2-(oxidomethyl)phenyl]iminomethyl}phenolate; DMSO is dimethyl sulfoxide) are bridged by two O atoms, with an Fe...Fe separation of 3.1838 (8) Å. The coordination polyhedron of the FeIII atoms can be described as distorted octahedral, with four Fe—O, one Fe—N and one Fe—Cl coordination bonds. The L ligand is not planar, the dihedral angle between the 2-(oxidomethyl)phenyl]imino and 4-nitro-2-(iminomethyl)phenolate planes being 48.54 (9)°. The solvent DMSO molecule is disordered over two orientations with equal occupancy