6,204 research outputs found
Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom
Background
Little epidemiological evaluation of recurrent seizure disorders in cats currently exists in veterinary literature.
Objectives
To report the prevalence and risk factors for recurrent seizure disorders (RSD) and epilepsy in cats presented to primary care veterinary practices in the United Kingdom (UK).
Animals
A total of 285â547 cats under veterinary care during 2013 presenting to 282 primary care clinics in the UK.
Methods
Cohort study using multivariable logistic regression modeling for risk factor analysis.
Results
There were 458 confirmed RSD cases, giving a 1âyear period prevalence of 0.16% (95% confidence interval [CI], 0.15â0.18). A subset of 114 (24.89%) cases was recorded as having epilepsy, giving a 1âyear period prevalence of 0.04% (95% CI, 0.03â0.5). Increasing age was significantly associated with increasing odds of RSD. Breed, sex, neuter status, and body weight were not associated with RSD. Epilepsy was most frequently diagnosed in adult to middleâaged cats. Cats aged 3.0 to <6.0âyears had 3.32 times higher odds of epilepsy diagnosis compared to cats <3.0âyears of age. Insured cats were more likely to be diagnosed with epilepsy compared to noninsured cats.
Conclusions and Clinical Importance
Although less common than in dogs, RSD and epilepsy still comprise an important disorder group in the UK cat population. Aging is a significant risk factor for these disorders in cats
ASMs and Operational Algorithmic Completeness of Lambda Calculus
We show that lambda calculus is a computation model which can step by step
simulate any sequential deterministic algorithm for any computable function
over integers or words or any datatype. More formally, given an algorithm above
a family of computable functions (taken as primitive tools, i.e., kind of
oracle functions for the algorithm), for every constant K big enough, each
computation step of the algorithm can be simulated by exactly K successive
reductions in a natural extension of lambda calculus with constants for
functions in the above considered family. The proof is based on a fixed point
technique in lambda calculus and on Gurevich sequential Thesis which allows to
identify sequential deterministic algorithms with Abstract State Machines. This
extends to algorithms for partial computable functions in such a way that
finite computations ending with exceptions are associated to finite reductions
leading to terms with a particular very simple feature.Comment: 37 page
A mapping approach to synchronization in the "Zajfman trap": stability conditions and the synchronization mechanism
We present a two particle model to explain the mechanism that stabilizes a
bunch of positively charged ions in an "ion trap resonator" [Pedersen etal,
Phys. Rev. Lett. 87 (2001) 055001]. The model decomposes the motion of the two
ions into two mappings for the free motion in different parts of the trap and
one for a compressing momentum kick. The ions' interaction is modelled by a
time delay, which then changes the balance between adjacent momentum kicks.
Through these mappings we identify the microscopic process that is responsible
for synchronization and give the conditions for that regime.Comment: 12 pages, 9 figures; submitted to Phys Rev
Computable functions, quantum measurements, and quantum dynamics
We construct quantum mechanical observables and unitary operators which, if
implemented in physical systems as measurements and dynamical evolutions, would
contradict the Church-Turing thesis which lies at the foundation of computer
science. We conclude that either the Church-Turing thesis needs revision, or
that only restricted classes of observables may be realized, in principle, as
measurements, and that only restricted classes of unitary operators may be
realized, in principle, as dynamics.Comment: 4 pages, REVTE
New XMM-Newton analysis of three bright X-ray sources in M31 globular clusters, including a new black hole candidate
We present detailed analysis of three globular cluster X-ray sources in the
XMM-Newton extended survey of M31. The X-ray counterpart to the M31 globular
cluster Bo 45 (XBo 45) was observed with XMM-Newton on 2006 December 26. Its
combined pn+MOS 0.3--10 keV lightcurve exhibited a r.m.s variability of ~10%,
and its 0.3--7.0 keV emission spectrum was well described by an absorbed power
law with photon index 1.440.12. Its variability and emission is
characteristic of low mass X-ray binaries (LMXBs) in the low-hard state,
whether the accretor is a neutron star or black hole. Such behaviour is
typically observed at luminosities \la10% Eddington. However, XBo 45
exhibited this behaviour at an unabsorbed, 0.3--10 keV luminosity of
2.5 erg s, or{~140%} Eddington for a 1.4
neutron star accreting hydrogen. Hence, we identify XBo 45 as a new
candidate black hole LMXB. XBo 45 appears to have been consistently bright for
~30 years, consistent with theoretical prediction for a globular cluster black
hole binary formed via tidal capture. Bo 375 was observed in the 2007, January
2 XMM-Newton observation, and has a two-component spectrum that is typical for
a bright neutron star LMXB. Bo 135 was observed in the same field as Bo 45, and
could contain either a black hole or neutron star.Comment: Accepted by ApJ, 16 pages, 5 figures. This version includes the final
changes made at the request of the refere
The Structure and X-ray Recombination Emission of a Centrally Illuminated Accretion Disk Atmosphere and Corona
We model an accretion disk atmosphere and corona photoionized by a central
X-ray continuum source. We calculate the opacity and radiation transfer for an
array of disk radii, to obtain the two-dimensional structure of the disk and
its X-ray recombination emission. The atmospheric structure is insensitive to
the viscosity alpha. We find a feedback mechanism between the disk structure
and the central illumination, which expands the disk and increases the solid
angle subtended by the atmosphere. We model the disk of a neutron star X-ray
binary. We map the temperature, density, and ionization structure of the disk,
and we simulate the high resolution spectra observable with the Chandra and
XMM-Newton grating spectrometers. The X-ray emission lines from the disk
atmosphere are detectable, especially for high-inclination binary systems. The
grating observations of two classes of X-ray binaries already reveal important
spectral similarities with our models. The line spectrum is very sensitive to
the structure of each atmospheric layer, and it probes the heating mechanisms
in the disk. The model spectrum is dominated by double-peaked lines of H-like
and He-like ions, plus weak Fe L. Species with a broad range of ionization
levels coexist at each radius: from Fe XXVI in the hot corona, to C VI at the
base of the atmosphere. The choice of stable solutions affects the spectrum,
since a thermal instability is present in the regime where the X-ray
recombination emission is most intense.Comment: 32 pages, incl. 26 figures, accepted for publication in Ap
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