Epidemiology of Traumatic Head Injury in Korean Children

The aim of this study was to elucidate the epidemiology of traumatic head injury (THI) among Korean children. A prospective, in-depth trauma survey was conducted in five teaching hospitals. Data from all of the children who attended the emergency department (ED) were analyzed. From June 2008 to May 2009, 2,856 children with THI visited the 5 EDs. The average age of the subjects was 5.6 (SD ± 4.9) yr old, and 1,585 (55.5%) were 0-4 yr old. The male-to-female ratio was 2.3 to 1 (1,979 vs 877). Consciousness levels of the subjects were classified according to the Glasgow Coma Scale (GCS), and 99.1%, 0.6%, and 0.4% were determined as mild, moderate, or severe injury, respectively, according to the GCS categorization. Most injuries occurred at home (51.3%), and the most common mechanism of injury was collision (43.2%). With regard to outcome, 2,682 (93.9%) patients were sent home, and 35 (1.2%) were transferred to another hospital. A total of 133 (4.7%) patients were hospitalized, and 38 (1.3%) underwent surgery. The incidence and characteristics of pediatric THI in Korea are affected by sex, location and injury mechanism

(18)F-FDG PET/CT in mediastinal lymph node staging of non-small-cell lung cancer in a tuberculosis-endemic country: consideration of lymph node calcification and distribution pattern to improve specificity

The aim of the study was to assess the accuracy of (18)F-fluorodeoxyglucose (FDG) PET/CT in mediastinal lymph node staging of patients with non-small-cell lung cancer (NSCLC) in a region with a high prevalence of granulomatous disease. Between March 2004 and February 2006, all patients with NSCLC underwent FDG PET/CT and contrast-enhanced thoracic CT, and subsequent surgical resection. PET/CT and contrast-enhanced CT images of 182 patients (126 men and 56 women; mean age 60.7 years) with NSCLC were acquired. Mediastinal node staging was determined using the American Joint Committee on Cancer (AJCC) staging system. Surgical and histological findings served as the reference standard. A total of 182 patients with 778 mediastinal node stations were evaluated. Sensitivity and specificity of contrast-enhanced CT were 36% and 80% on a per-patient basis and 23% and 92% on a per-node station basis. Sensitivity and specificity of PET/CT were 81% and 73% on a per-patient basis and 75% and 85% on a per-node station basis. After lymph nodes with calcification and bilateral hilar distribution were considered benign, sensitivity and specificity of PET/CT were 75% and 89% on a per-patient basis and 66% and 96% on a per-node station basis. This prospective study suggests that FDG PET/CT can more accurately stage mediastinal lymph nodes than CT. Considering lymph node calcification and distribution pattern could improve specificity at the cost of a decrease in sensitivity.Yen RF, 2008, EUR J NUCL MED MOL I, V35, P1305, DOI 10.1007/s00259-008-0733-1Bayman NA, 2008, CLIN LUNG CANCER, V9, P92TIEU BH, 2008, THORAC SURG CLIN, V18, P403HWANGBO B, 2008, CHESTKim YK, 2007, CANCER, V109, P1068, DOI 10.1002/cncr.22518Kim BT, 2006, RADIOLOGY, V241, P501, DOI 10.1148/radiol.2412051173Shim SS, 2005, RADIOLOGY, V236, P1011, DOI 10.1148/radiol.2363041310Cerfolio RJ, 2004, ANN THORAC SURG, V78, P1017, DOI 10.1016/j.athorascur.2004.02.067Detterbeck FC, 2004, CHEST, V125, P2300Rohren EM, 2004, RADIOLOGY, V231, P305, DOI 10.1148/radiol.2312021185Verhagen AFT, 2004, LUNG CANCER-J IASLC, V44, P175, DOI 10.1016/j.lungcan.2003.11.007Halter G, 2004, THORAC CARDIOV SURG, V52, P96, DOI 10.1055/s-2004-817844Kang WJ, 2004, EUR J NUCL MED MOL I, V31, P202, DOI 10.1007/s00259-003-1368-xSchrevens L, 2004, ONCOLOGIST, V9, P633Cerfolio RJ, 2003, ANN THORAC SURG, V76, P861Lardinois D, 2003, NEW ENGL J MED, V348, P2500SILVESTRI GA, 2003, CHEST, V123, P147TOLOZA EM, 2003, CHEST, V123, P157GREENE FL, 2002, AJCC CANC STAGING HDFischer BMB, 2001, LANCET ONCOL, V2, P659Kamiyoshihara M, 2001, J CARDIOVASC SURG, V42, P119Pieterman RM, 2000, NEW ENGL J MED, V343, P254Farrell MA, 2000, RADIOLOGY, V215, P886Ko JP, 2000, AM J ROENTGENOL, V174, P775Hong YP, 1998, INT J TUBERC LUNG D, V2, P27Gdeedo A, 1997, EUR RESPIR J, V10, P1547Mountain CF, 1997, CHEST, V111, P1710Mountain CF, 1997, CHEST, V111, P1718Hoh CK, 1997, SEMIN NUCL MED, V27, P94Takizawa T, 1997, J THORAC CARDIOV SUR, V113, P248Strauss LG, 1996, EUR J NUCL MED, V23, P1409MCLOUD TC, 1992, RADIOLOGY, V182, P319