550 research outputs found

    Anticipation of Subsequent Days

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    This thesis exhibition is a presentation of my research into historic and autoethnographic analyses of social, material, and technical practices that support the production of atmospheric-fired stoneware and porcelain vessels. My work examines contemporary ceramic processes of wood-firing, salt-glazing and wood ash glazes and how they continue craft practices of historic traditions. By critically examining the ceramic studio as a ground for material and ethnographic research, I aim to better understand the social conditions that support and produce atmospheric-fired ceramic practices in the 21st century, as well as how and why we continue to create such pots. My practice-based research involves the procedures of wheel-thrown ceramics and atmospheric-firing, and the use of locally sourced glazes. I am fascinated by the interaction of clay, sodium vapors and wood ash; how ceramic material and kiln technology have the ability to produce a ceramic surface that directly references the ceramic process. My object-based work finds inspiration from the aesthetic qualities found in the salt-glazed ceramics of 13th to 17th century Western Europe, 16th century Japanese Shigaraki ceramics and the pottery of colonial America. Embedded within my work is recognition of ceramic history coupled with a reflection on contemporary life

    Mechatronics & the cloud

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    Conventionally, the engineering design process has assumed that the design team is able to exercise control over all elements of the design, either directly or indirectly in the case of sub-systems through their specifications. The introduction of Cyber-Physical Systems (CPS) and the Internet of Things (IoT) means that a design team’s ability to have control over all elements of a system is no longer the case, particularly as the actual system configuration may well be being dynamically reconfigured in real-time according to user (and vendor) context and need. Additionally, the integration of the Internet of Things with elements of Big Data means that information becomes a commodity to be autonomously traded by and between systems, again according to context and need, all of which has implications for the privacy of system users. The paper therefore considers the relationship between mechatronics and cloud-basedtechnologies in relation to issues such as the distribution of functionality and user privacy

    An analysis of decision making strategies used by P-3 pilots in hazardous situations

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    Effective decision making in aeronautical environments, which often involves high elements of risk, is critical to mission success. Unfortunately, no proven methodology exists to train pilots to make successful decisions. Cockpit decision making has relied on traditional analytical models and methodologies that underestimate the role of pilot experience, expertise and judgement Naturalistic Decision Making models (NDM) contend that decision makers facing real-world decisions use experience and judgement to make timely decisions without analyzing a multitude of alternatives. This thesis analyzes 438 P-3 aviation hazard reports (hazreps) to ascertain which cognitive strategies from either the analytical or naturalistic methodology are more appropriate for handling malfunctions situations. The author presents a hybrid model of decision making by P-3 pilots based on the results of the analysis and strategies from both methodologies. This thesis recommends that decision making training be treated as a core activity of pilots not only in flight school, but alter qualification is complete. Training pilots to become experts will improve situational awareness and reduce the number of unfavorable outcomes in hazardous situations.http://archive.org/details/annalysisofdecis109459389U.S. Navy (U.S.N.) author.Approved for public release; distribution is unlimited

    Consequences of Post-Weaning Social Isolation on Anxiety Behavior and Related Neural Circuits in Rodents

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    Exposure to adverse experiences in early-life is implicated in the later vulnerability to development of psychiatric disorders, including anxiety and affective disorders in humans. Adverse early-life experiences likely impart their long-term consequences on mental health by disrupting the normal development of neural systems involved in stress responses, emotional behavior and emotional states. Neural systems utilizing the neurotransmitters serotonin, dopamine and the neuropeptide corticotropin-releasing factor (CRF) are implicated in mediating emotive behaviors, and dysfunction of these neurochemical systems is associated with mood/anxiety disorders. These neural systems continue maturing until early or mid-adolescence in humans, thus alterations to their development are likely to contribute to the long-term consequences of adverse early-life experiences. A large body of literature suggests that post-weaning isolation rearing of rodents models the behavioral consequences of adverse early-life experiences in humans. Overall, the majority findings suggest that post-weaning social isolation that encompasses pre-adolescence produces long-lasting alterations to anxiety behavior, while measures of monoaminergic activity in various limbic regions during social isolation suggest alterations to dopamine and serotonin systems. The goal of this review is to evaluate and integrate findings from post-weaning social isolation studies specifically related to altered fear and anxiety behaviors and associated changes in neuroendocrine function and the activity of monoaminergic systems

    Stakeholder views on the design of National Health Service perinatal mental health services : 360-degree survey

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    Acknowledgements We are grateful to all respondents – to staff who took time from busy pandemic practice, and to patients and former patients and their families who provided the voice of lived experience. We also thank the LATNEM local peer support group, who provided support to our project and disseminated the survey on their media sites. Funding This research received no specific grant from any funding agency, commercial or not-for-profit sectors.Peer reviewedPublisher PD

    Furfuryl Alcohol Emulsion Resins as Co-Binders for Urea-Formaldehyde Resin-Bonded Particleboards

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    An approach to using water-insoluble furfuryl alcohol (FA) resins as a co-binder for particleboard (PB) urea-formaldehyde (UF) resins was evaluated. Sprayable FA/UF mixed resins were made by emulsifying FA resins of varying advancements and mixing with various formaldehyde to urea (F/U) ratio UF resins in various proportions. The binder performance of the mixed FA/UF resins was then evaluated by bonding laboratory PBs using a weakly acidic ordinary UF resin curing catalyst at various hot pressing temperatures. The PBs were also heat-treated and were aged for two years at room temperature. The test results of bond strengths and formaldehyde emission levels of PBs showed promising improvements at about 30% FA resin additions, although the results were preliminary due to the variable performance nature of such binder systems

    Myosin 10 is involved in murine pigmentation.

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    Myosins are molecular motors that are well known for their role in cell movement and contractile functions. Although extensively studied in muscle physiology, little is known about the function of myosins in mammalian skin. As part of the Sanger Institute Mouse Genetics Project, we have identified a role for Myo10 in pigmentation, with a phenotype unlike those of Myo5a or Myo7a. Adult mice homozygous for a disrupted Myo10 allele on a C57BL/6N background displayed a high degree of penetrance for white patches on their abdomen and dorsal surface. Forepaw syndactyly and hind paw syndactyly were also observed in these mice. Tail epidermal wholemounts showed a complete lack of melanocytes in the hair follicles and interfollicular epidermis. Myo10 has previously been implicated in human pigmentation. Our current study reveals involvement of Myo10 in murine skin pigmentation
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