22 research outputs found

    A role for mathematics in the physical sciences

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    Abstract Conflicting accounts of the role of mathematics in our physical theories can be traced to two principles. Mathematics appears to be both (1) theoretically indispensable, as we have no acceptable non-mathematical versions of our theories, and (2) metaphysically dispensable, as mathematical entities, if they existed, would lack a relevant causal role in the physical world. I offer a new account of a role for mathematics in the physical sciences that emphasizes the epistemic benefits of having mathematics around when we do science. This account successfully reconciles theoretical indispensability and metaphysical dispensability and has important consequences for both advocates and critics of indispensability arguments for platonism about mathematics

    Alcohol use as a risk factor for tuberculosis – a systematic review

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    <p>Abstract</p> <p>Background</p> <p>It has long been evident that there is an association between alcohol use and risk of tuberculosis. It has not been established to what extent this association is confounded by social and other factors related to alcohol use. Nor has the strength of the association been established. The objective of this study was to systematically review the available evidence on the association between alcohol use and the risk of tuberculosis.</p> <p>Methods</p> <p>Based on a systematic literature review, we identified 3 cohort and 18 case control studies. These were further categorized according to definition of exposure, type of tuberculosis used as study outcome, and confounders controlled for. Pooled effect sizes were obtained for each sub-category of studies.</p> <p>Results</p> <p>The pooled relative risk across all studies that used an exposure cut-off level set at 40 g alcohol per day or above, or defined exposure as a clinical diagnosis of an alcohol use disorder, was 3.50 (95% CI: 2.01–5.93). After exclusion of small studies, because of suspected publication bias, the pooled relative risk was 2.94 (95% CI: 1.89–4.59). Subgroup analyses of studies that had controlled for various sets of confounders did not give significantly different results and did not explain the significant heterogeneity that was found across the studies.</p> <p>Conclusion</p> <p>The risk of active tuberculosis is substantially elevated in people who drink more than 40 g alcohol per day, and/or have an alcohol use disorder. This may be due to both increased risk of infection related to specific social mixing patterns associated with alcohol use, as well as influence on the immune system of alcohol itself and of alcohol related conditions.</p

    Explanatory Relevance and Contrastive Explanation

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    Abstract Explanations in Science

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    Russel et l'empirisme logique

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    Christopher Pincock analyses the evolution of the Russellian theory of induction and compares it to Reichenbach's.Christopher Pincock, Professeur de philosophie à l’université d’État de l’Ohio (Ohio State University, États-Unis).Christopher Pincock analyse l’évolution de la théorie russellienne de l’induction et la compare à celle de Reichenbach

    Models and simulations

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    N° de la revue Synthès
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