15,941 research outputs found

    Essential Fish Habitat project status report

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    : Groundfish that associate with rugged seafloor types are difficult to assess with bottom-trawl sampling gear. Simrad ME70 multibeam echosounder (MBES) data and video imagery were collected to characterize trawlable and untrawlable areas, and to ultimately improve efforts to determine habitat-specific groundfish biomass. The data were collected during two acoustic-trawl surveys of the Gulf of Alaska (GOA) during 2011 and 2012 by NOAA Alaska Fisheries Science Center (AFSC) researchers. MBES data were collected continuously along the trackline, which included parallel transects (1-20 nmi spacing) and fine-scale survey locations in 2011. Video data were collected at camera stations using a drop camera system. Multibeamderived seafloor metrics were overlaid with the locations of previously conducted AFSC bottomtrawl (BT) survey hauls and 2011 camera stations. Generalized linear models were used to identify the best combination of multibeam metrics to discriminate between trawlable and untrawlable seafloor for the region of overlap between the camera stations or haul paths and the MBES data. The most discriminatory models were chosen based on the Akaike information criterion (AIC). The two best models were developed using data collected at camera stations with either oblique incidence backscatter strength (Sb) or mosaic Sb in combination with bathymetric position index and seafloor ruggedness and described over 54% of the variation between trawlable and untrawlable seafloor types. A map of predicted seafloor trawlability produced from the model using mosaic Sb and benthic-terrain metrics demonstrated that 58% of the area mapped (5,987 km2 ) had \u3e 50% probability of being trawlable and 42% of being untrawlable. The model predicted 69% of trawlable and untrawlable haul locations correctly. Successful hauls occurred in areas with 62% probability of being trawlable and haul locations with gear damage occurred in areas with a 38% probability of being trawlable. This model and map produced from multibeamderived seafloor metrics may be used to refine seafloor interpretation for the AFSC BT surveys and to advance efforts to develop habitat-specific biomass estimates for GOA groundfish populations

    Picosecond time-resolved pure-rotational coherent anti-Stokes Raman spectroscopy for N-2 thermometry

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    This paper was published in Optics Letters and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=ol-34-23-3755. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.Peer reviewedPublisher PD

    An investigation of the response of a hovercraft to surfaces performing heaving and pitching motions

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    The rapid development of hovercraft during the past decade has involved a concentrated effort on research and development to overcome the problems associated with a new form of transport. Some of the problems have not yet been solved and, in particular, the question of ride and stability characteristics is most important. An experimental and theoretical study has been made to achieve a method of prediction of stiffness and damping parameters through the change of cushion pressure during forcing of the cushion. [Continues.

    Sparse Bayesian mass-mapping with uncertainties: hypothesis testing of structure

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    A crucial aspect of mass-mapping, via weak lensing, is quantification of the uncertainty introduced during the reconstruction process. Properly accounting for these errors has been largely ignored to date. We present results from a new method that reconstructs maximum a posteriori (MAP) convergence maps by formulating an unconstrained Bayesian inference problem with Laplace-type 1\ell_1-norm sparsity-promoting priors, which we solve via convex optimization. Approaching mass-mapping in this manner allows us to exploit recent developments in probability concentration theory to infer theoretically conservative uncertainties for our MAP reconstructions, without relying on assumptions of Gaussianity. For the first time these methods allow us to perform hypothesis testing of structure, from which it is possible to distinguish between physical objects and artifacts of the reconstruction. Here we present this new formalism, demonstrate the method on illustrative examples, before applying the developed formalism to two observational datasets of the Abel-520 cluster. In our Bayesian framework it is found that neither Abel-520 dataset can conclusively determine the physicality of individual local massive substructure at significant confidence. However, in both cases the recovered MAP estimators are consistent with both sets of data

    The Role of Nitroreductases in Resistance to Nitroimidazoles

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    Antimicrobial resistance is a major challenge facing modern medicine, with an estimated 700,000 people dying annually and a global cost in excess of $100 trillion. This has led to an increased need to develop new, effective treatments. This review focuses on nitroimidazoles, which have seen a resurgence in interest due to their broad spectrum of activity against anaerobic Gram-negative and Gram-positive bacteria. The role of nitroreductases is to activate the antimicrobial by reducing the nitro group. A decrease in the activity of nitroreductases is associated with resistance. This review will discuss the resistance mechanisms of different disease organisms, including Mycobacterium tuberculosis, Helicobacter pylori and Staphylococcus aureus, and how these impact the effectiveness of specific nitroimidazoles. Perspectives in the field of nitroimidazole drug development are also summarised
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