19 research outputs found
Teaching Sodium Fast Reactor Technology and Operation for the Present and Future Generations of SFR Users
International audienceThis paper provides a description of the education and training activities related to sodium fast reactors, carried out respectively in the French Sodium and Liquid Metal School (ESML) created in 1975 and located in France (at the CEA Cadarache Research Centre), in the Fast Reactor Operation and Safety School (FROSS) created in 2005 at the Phenix plant, and in the Institut National des Sciences et Techniques Nucle'aires (INSTN). It presents their recent developments and the current collaborations throughout the world with some other nuclear organizations and industrial companies. Owing to these three entities, CEA provides education and training sessions for students, researchers, and operators involved in the operation or development of sodium fast reactors and related experimental facilities. The sum of courses provided by CEA through its sodium school, FROSS, and INSTN organizations is a unique valuable amount of knowledge on sodium fast reactor design, technology, safety and operation experience, decommissioning aspects and practical exercises. It is provided for the national demand and, since the last ten years, it is extensively opened to foreign countries. Over more than 35 years, the ESML, FROSS, and INSTN have demonstrated their flexibility in adapting their courses to the changing demand in the sodium fast reactor field, operation of PHENIX and SUPERPHENIX plants, and decommissioning and dismantling operations. The results of this ambitious and constant strategy are first sharing of knowledge obtained from experimental studies carried out in research laboratories and operational feedback from reactors, secondly standardized information on safety, and finally the creation of a ''sodium community'' that debates, shares the knowledge, and suggests new tracks for a better definition of design and operating rules
Evolution of an endofungal Lifestyle: Deductions from the Burkholderia rhizoxinica Genome
<p>Abstract</p> <p>Background</p> <p><it>Burkholderia rhizoxinica </it>is an intracellular symbiont of the phytopathogenic zygomycete <it>Rhizopus microsporus</it>, the causative agent of rice seedling blight. The endosymbiont produces the antimitotic macrolide rhizoxin for its host. It is vertically transmitted within vegetative spores and is essential for spore formation of the fungus. To shed light on the evolution and genetic potential of this model organism, we analysed the whole genome of <it>B. rhizoxinica </it>HKI 0454 - a type strain of endofungal <it>Burkholderia </it>species.</p> <p>Results</p> <p>The genome consists of a structurally conserved chromosome and two plasmids. Compared to free-living <it>Burkholderia </it>species, the genome is smaller in size and harbors less transcriptional regulator genes. Instead, we observed accumulation of transposons over the genome. Prediction of primary metabolic pathways and transporters suggests that endosymbionts consume host metabolites like citrate, but might deliver some amino acids and cofactors to the host. The rhizoxin biosynthesis gene cluster shows evolutionary traces of horizontal gene transfer. Furthermore, we analysed gene clusters coding for nonribosomal peptide synthetases (NRPS). Notably, <it>B. rhizoxinica </it>lacks common genes which are dedicated to quorum sensing systems, but is equipped with a large number of virulence-related factors and putative type III effectors.</p> <p>Conclusions</p> <p><it>B. rhizoxinica </it>is the first endofungal bacterium, whose genome has been sequenced. Here, we present models of evolution, metabolism and tools for host-symbiont interaction of the endofungal bacterium deduced from whole genome analyses. Genome size and structure suggest that <it>B. rhizoxinica </it>is in an early phase of adaptation to the intracellular lifestyle (genome in transition). By analysis of tranporters and metabolic pathways we predict how metabolites might be exchanged between the symbiont and its host. Gene clusters for biosynthesis of secondary metabolites represent novel targets for genomic mining of cryptic natural products. <it>In silico </it>analyses of virulence-associated genes, secreted proteins and effectors might inspire future studies on molecular mechanisms underlying bacterial-fungal interaction.</p
Bases biochimiques membranaires dans le developpement de la dependance alcoolique : roles respectifs de l'ethanol et de l'acetaldehyde
SIGLECNRS T Bordereau / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc
Contribution à l'étude et à la modélisation de la pyro-gazéification de biomasse par plasma thermique
Ce travail porte sur l étude d un procédé innovant de pyro-gazéification de bio-huile utilisant un plasma thermique, afin de produire un gaz riche en CO/H2. Plus précisément, cette thÚse vise à comprendre et modéliser les mécanismes jouant un rÎle clé lors de la transformation thermochimique de bio-huile dans un écoulement plasma. Tout d abord, une étude bibliographique portant sur la phénoménologie et la modélisation des interactions plasma liquide a été réalisée. Elle a conduit à la définition d une double approche, expérimentale et numérique. Les études expérimentales ont permis d identifier trois paramÚtres influents lors de la conversion de molécules organiques en milieu plasma : le rapport entre l enthalpie spécifique du jet de plasma et l enthalpie réactionnelle, la nature du gaz plasmagÚne et le mode d injection des réactifs. Enfin, les résultats numériques, obtenus avec le code de mécanique des fluides Fluent, viennent confirmer et extrapoler les tendances expérimentales.This work is devoted to the study of an innovating allothermal process consisting in the thermochemical transformation of bio-oil by using thermal plasma in order to produce a high-value syngas. More precisely, the present study aims to understand and model the mechanisms playing a key role in the gasification of a liquid jet of bio-oil injected in a plasma cross-flow. First, a literature survey on the phenomena and modelling of the plasma liquid interactions is presented. It led to the definition of a methodology combining an experimental and a numerical approach. The experimental works showed the effect of three main parameters during the conversion of organic compounds under thermal plasma conditions: the ratio between the specific plasma enthalpy to reaction enthalpy, the nature of the plasma-forming gas and the geometry of bio-oil injection. Lastly, the numerical results, obtained with Fluent software, confirmed and made it possible to extrapolate the experimental trends.nships between the 3rd order NLO properties of tellurites and their structural arrangements (entities connection, tellurium lone pair).LIMOGES-BU Sciences (870852109) / SudocSudocFranceF
Teaching Sodium Fast Reactors in CEA
International audienceAmong the Fast Neutron Reactor Systems, the SFR has the most comprehensive technological basis as result of the experience gained from worldwide operation of several experimental, prototype, and commercial size reactors since the 1940s. This experience corresponds to about 402 years of operation by end of 2010. Six reactors are in operation BOR60, BN600 and BN800 in Russia, Joyo in Japan, FBTR in India and CEFR in China. One reactor is being commissioned PFBR (500MWe) in India and several projects are currently developed FBR1 and 2 in India, BN1200 in Russia, JSFR in Japan, PGSFR in Korea, CFR-600 in China and ASTRID in France. In order to support operation of existing reactors, design activities for new projects and decommissioning of old reactors, it is mandatory to develop skills, more particularly among the young generation, who will operate these new reactors. In addition, education and training is also essential to share the knowledge among the teams involved in Research and Development. Several strategies are developed at the national level, or within multilateral framework, like EU or IAEA to support development of Fast Reactors.In France, to answer to this increasing demand of Education and Training, four sessions are proposed, within the frame of INSTN (French National Institute for Nuclear Science and Technology)-SFR History, main options, design and operational feedback-SFR Functional analysis and design-SFR Safety and operation-SFR Sodium structures interactionsThe French Na School (ESML) provides since 1975 also several sessions dedicated to Na facilities design, safe operation, handling, and also decommissioning and sodium treatment. Beside courses, practical exercises are organized during each session. 10 different modules are available, ranging in length from 1 to 5 days. CEA contributes also to the organization of European Sessions dedicated to Sodium Fast Reactors, organized within the frame of the European Commission (CP-ESFR, ESNII+ , ESFR-SMART) This Education and Training strategy is a key element for the future of the development of Sodium Fast Reactors, and more particularly ASTRID project. CEA is ready to share training experience and to collaborate with other foreign Education and Training Entities
Teaching Sodium Fast Reactors in CEA
International audienceAmong the Fast Neutron Reactor Systems, the SFR has the most comprehensive technological basis as result of the experience gained from worldwide operation of several experimental, prototype, and commercial size reactors since the 1940s. This experience corresponds to about 402 years of operation by end of 2010. Six reactors are in operation BOR60, BN600 and BN800 in Russia, Joyo in Japan, FBTR in India and CEFR in China. One reactor is being commissioned PFBR (500MWe) in India and several projects are currently developed FBR1 and 2 in India, BN1200 in Russia, JSFR in Japan, PGSFR in Korea, CFR-600 in China and ASTRID in France. In order to support operation of existing reactors, design activities for new projects and decommissioning of old reactors, it is mandatory to develop skills, more particularly among the young generation, who will operate these new reactors. In addition, education and training is also essential to share the knowledge among the teams involved in Research and Development. Several strategies are developed at the national level, or within multilateral framework, like EU or IAEA to support development of Fast Reactors.In France, to answer to this increasing demand of Education and Training, four sessions are proposed, within the frame of INSTN (French National Institute for Nuclear Science and Technology)-SFR History, main options, design and operational feedback-SFR Functional analysis and design-SFR Safety and operation-SFR Sodium structures interactionsThe French Na School (ESML) provides since 1975 also several sessions dedicated to Na facilities design, safe operation, handling, and also decommissioning and sodium treatment. Beside courses, practical exercises are organized during each session. 10 different modules are available, ranging in length from 1 to 5 days. CEA contributes also to the organization of European Sessions dedicated to Sodium Fast Reactors, organized within the frame of the European Commission (CP-ESFR, ESNII+ , ESFR-SMART) This Education and Training strategy is a key element for the future of the development of Sodium Fast Reactors, and more particularly ASTRID project. CEA is ready to share training experience and to collaborate with other foreign Education and Training Entities
Analyse et évaluationdu risque hydrogÚne dans un réacteur de fusion thermonucléaire
International audienc
Intake estimation of phytochemicals in a French well-balanced diet
International audiencePhytochemicals contribute to the health benefits of plant-rich diets, notably through their antioxidant and anti-inflammatory effects. However, recommended daily amounts of the main dietary phytochemicals remain undetermined. We aimed to estimate the amounts of phytochemicals in a well-balanced diet. A modelled diet was created, containing dietary reference intakes for adults in France. Two one-week menus (summer and winter) were devised to reflect typical intakes of plant-based foods. Existing databases were used to estimate daily phytochemical content for seven phytochemical families: phenolic acids, flavonoids (except anthocyanins), anthocyanins, tannins, organosulfur compounds, carotenoids, and caffeine. The summer and winter menus provided 1607 and 1441 mg/day, respectively, of total polyphenols (phenolic acids, flavonoids, anthocyanins, and tannins), the difference being driven by reduced anthocyanin intake in winter. Phenolic acids, flavonoids (including anthocyanins), and tannins accounted for approximately 50%, 25%, and 25% of total polyphenols, respectively. Dietary carotenoid and organosulfur compound content was estimated to be approximately 17 and 70 mg/day, respectively, in both seasons. Finally, both menus provided approximately 110 mg/day of caffeine, exclusively from tea and coffee. Our work supports ongoing efforts to define phytochemical insufficiency states that may occur in individuals with unbalanced diets and related disease risk factors
Le retour dâexpĂ©rience de la technologie sodium
Lâexploitation de PhĂ©nix a permis de valider la mise en oeuvre du sodium en tant que fluide caloporteur et la technologie associĂ©e. Elle montre aussi les voies de progrĂšs pour les futurs rĂ©acteurs. Cet article examine successivement : lâinstrumentation, la purification du sodium et les transferts de masse en sodium et dans la couverture gazeuse, les fuites de sodium, diffĂ©rents composants des circuits tels que les pompes Ă©lectromagnĂ©tiques, les vannes, les mĂ©langeurs et enfin les Ă©quipements de manutention