On Self-Organized Criticality and Synchronization in Lattice Models of Coupled Dynamical Systems

Lattice models of coupled dynamical systems lead to a variety of complex behaviors. Between the individual motion of independent units and the collective behavior of members of a population evolving synchronously, there exist more complicated attractors. In some cases, these states are identified with self-organized critical phenomena. In other situations, with clusterization or phase-locking. The conditions leading to such different behaviors in models of integrate-and-fire oscillators and stick-slip processes are reviewed.Comment: 41 pages. Plain LaTeX. Style included in main file. To appear as an invited review in Int. J. Modern Physics B. Needs eps

VLSI design of the tiny RISC microprocessor

This report describes the Tiny RISC microprocessor designed at UC Irvine. Tiny RISC is a 16-bit microprocessor and has a RISC-style architecture. The chip was fabricated by MOSIS [1] in a 2μm n-well CMOS technology. The processor has a cycle time of 70 ns

Investigation of the shear-mechanical and dielectric relaxation processes in two mono-alcohols close to the glass transition

Shear-mechanical and dielectric measurements on the two monohydroxy (mono-alcohol) molecular glass formers 2-ethyl-1-hexanol and 2-butanol close to the glass transition temperature are presented. The shear-mechanical data are obtained using the piezoelectric shear-modulus gauge method covering frequencies from 1mHz to 10kHz. The shear-mechanical relaxation spectra show two processes, which follow the typical scenario of a structural (alpha) relaxation and an additional (Johari-Goldstein) beta relaxation. The dielectric relaxation spectra are dominated by a Debye-type peak with an additional non-Debye peak visible. This Debye-type relaxation is a common feature peculiar to mono-alcohols. The time scale of the non-Debye dielectric relaxation process is shown to correspond to the mechanical structural (alpha) relaxation. Glass-transition temperatures and fragilities are reported based on the mechanical alpha relaxation and the dielectric Debye-type process, showing that the two glass-transition temperatures differ by approximately 10K and that the fragility based on the Debye-type process is a factor of two smaller than the structural fragility. If a mechanical signature of the Debye-type relaxation exists in these liquids, its relaxation strength is at most 1% and 3% of the full relaxation strength of 2-butanol and 2-ethyl-1-hexanol respectively. These findings support the notion that it is the non-Debye dielectric relaxation process that corresponds to the structural alpha relaxation in the liquid.Comment: 8 pages, 6 figures. Minor corrections, updated figures, more dielectric data show

Absence of an embryonic stem cell DNA methylation signature in human cancer.

BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture of cell types that are of fetal origin and are reminiscent of embryonic stem cell lineage. Here we implemented the FCO signature estimation method to compare the fraction of cells with the FCO signature in tumor tissues and their corresponding nontumor normal tissues.MethodsWe applied our FCO algorithm to discovery data sets obtained from The Cancer Genome Atlas (TCGA) and replication data sets obtained from the Gene Expression Omnibus (GEO) data repository. Wilcoxon rank sum tests, linear regression models with adjustments for potential confounders and non-parametric randomization-based tests were used to test the association of FCO proportion between tumor tissues and nontumor normal tissues. P-values of < 0.05 were considered statistically significant.ResultsAcross 20 different tumor types we observed a consistently lower FCO signature in tumor tissues compared with nontumor normal tissues, with 18 observed to have significantly lower FCO fractions in tumor tissue (total n = 6,795 tumor, n = 922 nontumor, P < 0.05). We replicated our findings in 15 tumor types using data from independent subjects in 15 publicly available data sets (total n = 740 tumor, n = 424 nontumor, P < 0.05).ConclusionsThe results suggest that cancer development itself is substantially devoid of recapitulation of normal embryologic processes. Our results emphasize the distinction between DNA methylation in normal tightly regulated stem cell driven differentiation and cancer stem cell reprogramming that involves altered methylation in the service of great cell heterogeneity and plasticity

77Se NMR Investigation of the K(x)Fe(2-y)Se(2) High Tc Superconductor (Tc=33K)

We report a comprehensive 77Se NMR study of the structural, magnetic, and superconducting properties of a single crystalline sample of the newly discovered FeSe-based high temperature superconductor K(x)Fe(2-y)Se(2) (Tc=33K) in a broad temperature range up to 290 K. We will compare our results with those reported for FeSe (Tc=9K) and FeAs-based high Tc systems.Comment: Final versio

The Electronic Correlation Strength of Pu

An electronic quantity, the correlation strength, is defined as a necessary step for understanding the properties and trends in strongly correlated electronic materials. As a test case, this is applied to the different phases of elemental Pu. Within the GW approximation we have surprisingly found a "universal" scaling relationship, where the f-electron bandwidth reduction due to correlation effects is shown to depend only on the local density approximation bandwidth and is otherwise independent of crystal structure and lattice constant.Comment: 7 pages, 4 figures, This version of the paper has been revised to add additional background informatio

Finiteness and Dual Variables for Lorentzian Spin Foam Models

We describe here some new results concerning the Lorentzian Barrett-Crane model, a well-known spin foam formulation of quantum gravity. Generalizing an existing finiteness result, we provide a concise proof of finiteness of the partition function associated to all non-degenerate triangulations of 4-manifolds and for a class of degenerate triangulations not previously shown. This is accomplished by a suitable re-factoring and re-ordering of integration, through which a large set of variables can be eliminated. The resulting formulation can be interpreted as a ``dual variables'' model that uses hyperboloid variables associated to spin foam edges in place of representation variables associated to faces. We outline how this method may also be useful for numerical computations, which have so far proven to be very challenging for Lorentzian spin foam models.Comment: 15 pages, 1 figur