Effects of interplanetary transport on derived energetic particle source strengths

We study the transport of solar energetic particles (SEPs) in the inner heliosphere in order to relate observations made by an observer at 1 AU to the number and total energy content of accelerated particles at the source, assumed to be near the Sun. We use a numerical simulation that integrates the trajectories of a large number of individual particles moving in the interplanetary magnetic field. We model pitch angle scattering and adiabatic cooling of energetic ions with energies from 50 keV nucleon^(−1) to 100 MeV nucleon^(−1). Among other things, we determine the number of times that particles of a given energy cross 1 AU and the average energy loss that they suffer because of adiabatic deceleration in the solar wind. We use a number of different forms of the interplanetary spatial diffusion coefficient and a wide range of scattering mean-free paths and consider a number of different ion species in order to generate a wide range of simulation results that can be applied to individual SEP events. We apply our simulation results to observations made at 1 AU of the 20 February 2002 solar energetic particle event, finding the original energy content of several species. We find that estimates of the source energy based on SEP measurements at 1 AU are relatively insensitive to the mean-free path and scattering scheme if adiabatic cooling and multiple crossings are taken into account

Update on alternative therapies for vulvovaginal atrophy

Although systemic absorption of estrogen with local treatment for vulvovaginal atrophy (VVA) is most likely to be negligible, it is unknown whether this minimal absorption will affect outcomes in women with breast cancer. Use of adjuvant therapy with aromatase inhibitors for breast cancer is associated with high incidence of VVA symptoms. Because of the impact of moderate to severe VVA symptoms on the quality of life in breast cancer survivors, there has been an intense search for alternative therapies. Further, the publicity that followed the publication of data from the Women’s Health Initiative Study has led to the suggestion by the medical community to use the lowest dose therapy possible for minimal time duration in order to avoid risks. This article will highlight the progress in alternative therapies for VVA

Efficacy and safety of ultra-low-dose Vagifem (10 mcg)

Vulvovaginal atrophy [VVA] is defined as inflammation of the vaginal epithelium due to atrophy secondary to decreased levels of circulating estrogen. There is currently only one approved method for the treatment of VVA, and that is the administration of exogenous estrogens. Overall, the ideal VVA treatment must have benefits, minimize risks, and enhance compliance in the patient while optimizing cost-effectiveness. Unfortunately, of the approximate 25% of symptomatic women that are thought to seek medical help, the proportion that receives hormone therapy may be small and its duration of use is short. Women have been very reluctant to take hormone therapy due to widely publicized results of the risks associated with hormone therapy. Thus, while menopausal hormone therapy was once accepted as the ideal approach for optimizing changes associated with menopause, prospective randomized clinical trials have challenged that view and have led to a marked decrease in the use of such therapy and increased search for low-dose therapies. This article will highlight the efficacy and safety of recently FDA-approved Vagifem (10 mcg) in treatment of VVA

Caractérisation des anneaux noethériens de séries formelles à croissance controlée. Application à la synthèse spectrale

Given a subring of the ring of formal power series defined by the growth of the coefficients, we prove a necessary and sufficient condition for it to be a noetherian ring. As a particular case, we show that the ring of Gevrey power series is a noetherian ring. Then, we get a spectral synthesis theorem for some classes of ultradifferentiable functions

Group-level Emotion Recognition using Transfer Learning from Face Identification

In this paper, we describe our algorithmic approach, which was used for submissions in the fifth Emotion Recognition in the Wild (EmotiW 2017) group-level emotion recognition sub-challenge. We extracted feature vectors of detected faces using the Convolutional Neural Network trained for face identification task, rather than traditional pre-training on emotion recognition problems. In the final pipeline an ensemble of Random Forest classifiers was learned to predict emotion score using available training set. In case when the faces have not been detected, one member of our ensemble extracts features from the whole image. During our experimental study, the proposed approach showed the lowest error rate when compared to other explored techniques. In particular, we achieved 75.4% accuracy on the validation data, which is 20% higher than the handcrafted feature-based baseline. The source code using Keras framework is publicly available.Comment: 5 pages, 3 figures, accepted for publication at ICMI17 (EmotiW Grand Challenge

Nonlinear lattice dynamics as a basis for enhanced superconductivity in YBa2Cu3O6.5

THz-frequency optical pulses can resonantly drive selected vibrational modes in solids and deform their crystal structure. In complex oxides, this method has been used to melt electronic orders, drive insulator to metal transitions or induce superconductivity. Strikingly, coherent interlayer transport strongly reminiscent of superconductivity can be transiently induced up to room temperature in YBa2Cu3O6+x. By combining femtosecond X-ray diffraction and ab initio density functional theory calculations, we determine here the crystal structure of this exotic non-equilibrium state. We find that nonlinear lattice excitation in normal-state YBa2Cu3O6+x at 100 K causes a staggered dilation/contraction of the Cu-O2 intra/inter- bilayer distances, accompanied by anisotropic changes in the in-plane O-Cu-O bond buckling. Density functional theory calculations indicate that these motions cause dramatic changes in the electronic structure. Amongst these, the enhancement in the dx2-y2 character of the in-plane electronic structure is likely to favor superconductivity.Comment: 28 pages, including Supplemen