Effect of Regular Plyometric Training on Growth-related Factors in Obesity Female Teenager

OBJECTIVES This study aimed to investigate the effect of regular plyometric training on growth-related factors in obese female teenager. METHODS The subjects of the study consisted of elementary school students group (EG, n=5) and middle school students group(MG, n=6), and overweight or obese experimenters were selected based on the ‘2017 Child and Adolescent Growth Chart Age Body Mass’ index. Exercise was conducted for 12 weeks. All measurements were carried out before and after exercise. The data processing was verified using the SPSS 26.0 statistical program to verify the correlation between paired t-test and Pearson in the 12-week pretraining and post-training groups. RESULTS After 12 weeks of plyometric training, there were significant differences in height(p=.002), ASIS(p=.003), body fat percentage(p=.018), and muscle mass(p=.014) among body composition of EG. There was a significant difference in height(p=.015) in body composition of MG. In the evaluation of muscle function, in muscle strength(60°/sec), (R)-FLE PT/bw(p=.011), (L)-FLE PT/bw(p=.017) in EG and muscle power(180°/sec), (R)-FLE PT/bw(p=.024), (L)-EXT PT/bw(p=.001), (R)-FLE TW/bw(p=.004) and (L)-EXT TW/bw(p=.012) showed a statistically significant difference. In terms of correlation, significant relationships were found between EG body fat mass and IGF-1(p<.05), and between body fat mass and IGF-1/IGF-BP3(p<.05). CONCLUSIONS Regular plyometric training had a positive effect on growth-related factors in obese female teenager

A Case of Hypertrophic Cranial Pachymeningitis Presenting with Scleritis in a Patient with Undifferentiated Connective Tissue Disease

Hypertrophic cranial pachymeningitis (HCP) is an uncommon disorder that causes a localized or diffuse thickening of the dura mater and has been reported to be infrequently associated with systemic autoimmune disorders such as Wegener's granulomatosis, rheumatoid arthritis, sarcoidosis, Behçet's disease, Sjögren syndrome, and temporal arteritis. Here, we report a case of HCP initially presented with scleritis and headache in a patient with undifferenciated connective tissue disease (UCTD). HCP was initially suspected on brain magnetic resonance imaging and defined pathologically on meningial biopsy. Immunologic studies showed the presence of anti-RNP antibody. After high dose corticosteroid therapy, the patient's symptoms and radiologic abnormalities of brain were improved. Our case suggested that HCP should be considered in the differential diagnosis of headache in a patient with UCTD presenting with scleritis

Automatic, Careful Online Packing of Groceries Using a Soft Robotic Manipulator and Multimodal Sensing

This thesis describes the use of soft robotic manipulators with multimodal sensing for estimating the physical properties of unknown objects to enable sorting and packing. Although bin packing has been a key benchmark task for robotic manipulation, the community has mainly focused on the placement of rigid rectilinear objects within the container. We address this by presenting a soft robotic hand that uses a combination of vision, motor-based proprioception and soft tactile sensors to identify and pack a stream of unknown objects. We translate the ill-defined human conception of a “well-packed container” into metrics that match combinations of our different sensor modalities and demonstrate how this works in a grocery packing scenario, where objects of arbitrary shape, size and stiffness come down a conveyor belt. The proposed multimodal approach is supported by physical experiments demonstrating how the integration of multiple sensing modalities can address complex manipulation applications.M.Eng

Low-Level Toxic Metal Exposure in Healthy Weaning-Age Infants: Association with Growth, Dietary Intake, and Iron Deficiency

Even low levels of toxic metal exposure (As, Cd, Hg, and Pb) in infancy might be harmful to children’s development. This study investigated toxic metal exposure on healthy weaning-age infants and its relationship with growth, diet, and iron/anemia status. The weight, height, head circumference, whole blood levels of four toxic metals, hemoglobin, and serum ferritin of healthy infants was measured. Among 210 infants with a median age of 11.4 months (interquartile range: 10.5–12.0), the median levels of As, Cd, Hg, and Pb were 1.2 μg/L, 0.05 μg/L, 0.8 μg/L, and 0.83 μg/dL, respectively. In adjusted linear regression models, post-birth weight gain (Pb) and current head circumference (As, Pb) were negatively associated with toxic metal levels. In multiple linear regression or logistic regression analysis, the duration of breastfeeding (all four metals), perceived adequacy of rice-based food intake (As), regular fish intake (As, Hg), and iron deficiency with/without anemia (Cd, Pb) were associated with increased toxic metal levels. Although levels of toxic metals may not usually be high in this population, individual exposure risk may need to be assessed after considering the type of feeding or intake of complementary foods and the iron/anemia status while evaluating growth status during late infancy

Whole-exome sequencing identifies recurrent AKT1 mutations in sclerosing hemangioma of lung.

Pulmonary sclerosing hemangioma (PSH) is a benign tumor with two cell populations (epithelial and stromal cells), for which genomic profiles remain unknown. We conducted exome sequencing of 44 PSHs and identified recurrent somatic mutations of AKT1 (43.2%) and β-catenin (4.5%). We used a second subset of 24 PSHs to confirm the high frequency of AKT1 mutations (overall 31/68, 45.6%; p.E17K, 33.8%) and recurrent β-catenin mutations (overall 3 of 68, 4.4%). Of the PSHs without AKT1 mutations, two exhibited AKT1 copy gain. AKT1 mutations existed in both epithelial and stromal cells. In two separate PSHs from one patient, we observed two different AKT1 mutations, indicating they were not disseminated but independent arising tumors. Because the AKT1 mutations were not found to co-occur with β-catenin mutations (or any other known driver alterations) in any of the PSHs studied, we speculate that this may be the single-most common driver alteration to develop PSHs. Our study revealed genomic differences between PSHs and lung adenocarcinomas, including a high rate of AKT1 mutation in PSHs. These genomic features of PSH identified in the present study provide clues to understanding the biology of PSH and for differential genomic diagnosis of lung tumors. Proc Natl Acad Sci U S A 2016 Sep 20; 113(38):10672-7